Dracinsky, Martin
Articles
Cerny, Miloslav;
Trnka, Tomas;
Budesinsky, Milos;
Dzoganova, Martina;
Dracinsky, Martin, Epoxide migration and pseudo-epoxide migration of 1,6:2,3- and 1,6:3,4-dianhydro-β-D-hexopyranoses. Synthesis of some deoxy halo derivatives of 1,6-anhydro-β-D-hexopyranoses. Collect. Czech. Chem. Commun. 2006, 7(10), 1497 - 1515, 10.1135/cccc20061497 
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Cisarova, Ivana;
Hrdina, Radim;
Dracinsky, Martin;
Hodacova, Jana;
Kotora, Martin;
Valterova, Irena, New pathway to C-symmetric atropoisomeric bipyridine N,N′-dioxides and solvent effect in enantioselective allylation of aldehydes. Advanced Synthesis and Catalysis 2008, 350(10), 1449 - 1456, 10.1002/adsc.200800141 .
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Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Hrebabecky, Hubert, Synthesis of novel conformationally locked carbocyclic nucleosides derived from 3-(hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol. Collect. Czech. Chem. Commun. 2006, 71(6), 871 - 888, 10.1135/cccc20060871 .
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Holy, Antonin;
Dracinsky, Martin;
Vrbkova, Silvie, Bifunctional acyclic nucleoside phosphonates: synthesis of chiral 9-{3-hydroxy[1,4-bis(phosphonomethoxy)]butan-2-yl} derivatives of purines. Tetrahedron Asymmetry 2007, 18(18), 2233 - 2247, 10.1016/j.tetasy.2007.09.021 .
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Holy, Antonin;
Dracinsky, Martin;
Vrbkova, Silvie, Synthesis of phosphonomethoxyethyl or 1,3-bis(phosphonomethoxy)propan-2-yl lipophilic esters of acyclic nucleoside phosphonates. Tetrahedron 2007, 63(46), 11391 - 11398, 10.1016/j.tet.2007.08.081 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert, Synthesis of novel carbocyclic nucleosides and pro-tides derived from 4-oxatricyclo[4.2.1.0]nonane-9-methanol. Collect. Czech. Chem. Commun. 2007, 72(10), 1331 - 1349, 10.1135/cccc20071331 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Dejmek, Milan, Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane. Collect. Czech. Chem. Commun. 2007, 72(11), 1523 - 1544, 10.1135/cccc20071523 .
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Holy, Antonin;
Dracinsky, Martin;
Vrbkova, Silvie, Bifunctional acyclic nucleoside phosphonates: 2. Symmetrical 2-{[bis(phosphono)methoxy]methyl}ethyl derivatives of purines and pyrimidines. Collect. Czech. Chem. Commun. 2007, 72(7), 965 - 983, 10.1135/cccc20070965 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin, Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy. Bioorganic and Medicinal Chemistry 2008, 16(14), 6778 - 6782, 10.1016/j.bmc.2008.05.058 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert, Synthesis of novel carbocyclic nucleoside analogues containing bicyclo[2.2.1]hept-2-ene-2-methanol. Collect. Czech. Chem. Commun. 2008, 73(1), 44 - 58, 10.1135/cccc20080044 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Neyts, Johan;
De Palma, Armando M., Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol. Collect. Czech. Chem. Commun. 2009, 74(3), 487 - 502, 10.1135/cccc2008204 .
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Holy, Antonin;
Dracinsky, Martin;
Fanfrlik, Jindrich;
Dolakova, Petra, Synthesis of analogues of Acyclic nucleoside diphosphates containing a (phosphonomethyl)phosphanyl moiety and studies of their phosphorylation. European Journal of Organic Chemistry 2009(7), 1082 - 1092, 10.1002/ejoc.200800911 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Neyts, Johan;
De Palma, Armando M., Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.0]nonane- 9-methanol and 4-oxatricyclo[4.3.1.0]decane-10-methanol, compounds with activity against coxsackie viruses. Collect. Czech. Chem. Commun. 2009, 74(3), 469 - 485, 10.1135/cccc2008193 .
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Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Dolakova, Petra;
Solinova, Veronika;
Kasicka, Vaclav, Acyclic nucleoside bisphosphonates: Synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines. European Journal of Medicinal Chemistry 2009, 44(6), 2408 - 2424, 10.1016/j.ejmech.2008.09.031 .
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Budesinsky, Milos;
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Kovackova, Sona, Isotopic exchange of hydrogen at C-5 in pyrimidine derivatives: tautomers with an sp-hybridised C-5 carbon atom. European Journal of Organic Chemistry 2009(24), 4117 - 4122, 10.1002/ejoc.200900529 .
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Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Hrebabecky, Hubert;
Sala, Michal;
Neyts, Johan;
De Palma, Armando M., Norbornane as the novel pseudoglycone moiety in nucleosides. Tetrahedron 2009, 65(45), 9291 - 9299, 10.1016/j.tet.2009.09.018 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert, New carbocyclic nucleoside analogues built on a bicyclo[2.2.2]octane-2,2- dimethanol template. Collect. Czech. Chem. Commun. 2009, 74(9), 1425 - 1441, 10.1135/cccc2009090 .
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Holy, Antonin;
Dracinsky, Martin;
Hockova, Dana, Synthesis and properties of a novel type of acyclic nucleoside phosphonates: 2-(purin-9-yl)ethoxyphenylphosphonic acids. European Journal of Organic Chemistry 2010(15), 2885 - 2892, 10.1002/ejoc.201000061 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Sala, Michal;
Nencka, Radim;
Neyts, Johan;
De Palma, Armando M.;
Leyssen, Pieter, Design, synthesis, and biological evaluation of novel coxsackievirus B3 inhibitors. Bioorganic and Medicinal Chemistry 2010, 18(12), 4374 - 4384, 10.1016/j.bmc.2010.04.081 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Cihlar, Tomas;
Naesens, Lieve;
Pomeisl, Karel;
Neyts, Johan;
Tichy, Tomas;
Brehova, Petra;
Laflamme, Genevieve;
Hui, Hon, Synthesis of ester prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] -2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. Journal of Medicinal Chemistry 2010, 53(19), 6825 - 6837, 10.1021/jm901828c .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Sala, Michal;
Cechova, Lucie, The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination reactions of purines. Tetrahedron 2011, 67(5), 866 - 871, 10.1016/j.tet.2010.12.040 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Chocholouasova, Jana;
Vacek, Jaroslav;
Kovackova, Soaa, Mechanism of the isotopic exchange reaction of the 5-H hydrogen of uracil derivatives in water and nonprotic solvents. European Journal of Organic Chemistry 2011(4), 777 - 785, 10.1002/ejoc.201001335 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Balzarini, Jan;
Klepetarova, Blanka;
Clercq, Erik de;
Janeba, Zlatko;
Baszczynski, Ondrej, Synthesis and antiviral activity of N-[3-fluoro-2- (phosphonomethoxy)propyl] analogues derived from N-substituted adenines and 2,6-diaminopurines. Bioorganic and Medicinal Chemistry 2011, 19(7), 2114 - 2124, 10.1016/j.bmc.2011.02.050 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Cesnek, Michal;
Janeba, Zlatko;
Baszczynski, Ondrej, Efficient and 'green' microwave-assisted synthesis of haloalkylphosphonates via the Michaelis-Arbuzov reaction. Green Chemistry 2011, 13(4), 882 - 888, 10.1039/c0gc00509f .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Tichy, Tomas, New prodrugs of Adefovir and Cidofovir. Bioorganic and Medicinal Chemistry 2011, 19(11), 3527 - 3539, 10.1016/j.bmc.2011.04.016 .
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Holy, Antonin;
Dracinsky, Martin;
Cesnek, Michal;
Janeba, Zlatko;
Brehova, Petra, The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling reaction. Tetrahedron 2011, 67(38), 7379 - 7385, 10.1016/j.tet.2011.07.040 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George, A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities. European Journal of Medicinal Chemistry 2011, 46(9), 3748 - 3754, 10.1016/j.ejmech.2011.05.040 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Balzarini, Jan;
Klepetarova, Blanka;
Janeba, Zlatko;
Baszczynski, Ondrej;
Hradil, Ondrej, An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids. Tetrahedron 2012, 68(3), 865 - 871, 10.1016/j.tet.2011.11.040 .
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Holy, Antonin;
Dracinsky, Martin;
Cesnek, Michal;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W.;
Jersey, John de;
Baszczynski, Ondrej, Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. Bioorganic and Medicinal Chemistry 2012, 20(2), 1076 - 1089, 10.1016/j.bmc.2011.11.034 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W., Synthesis of purine N-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents. Bioorganic and Medicinal Chemistry 2012, 20(3), 1222 - 1230, 10.1016/j.bmc.2011.12.034 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Mertlikova-Kaiserova, Helena;
Prochazkova, Eliska, Determination of the antioxidative activity of substituted 5-aminopyrimidines. Free Radical Research 2012, 46(1), 61 - 67, 10.3109/10715762.2011.638292 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Cechova, Lucie;
Mertlikova-Kaiserova, Helena;
Prochazkova, Eliska;
Brezinova, Anna, Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening. Bioorganic and Medicinal Chemistry Letters 2012, 22(20), 6405 - 6409, 10.1016/j.bmcl.2012.08.065 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
Guddat, Luke W.;
Baszczynski, Ondrej, The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. European Journal of Medicinal Chemistry 2013, 67, 81 - 89, 10.1016/j.ejmech.2013.06.032 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Mertlikova-Kaiserova, Helena;
Kolman, Viktor;
Kostinova, Alexandra, Efficient synthesis and biological properties of the 2'-trifluoromethyl analogues of acyclic nucleosides and acyclic nucleoside phosphonates. Collect. Czech. Chem. Commun. 2011, 76(10), 1187 - 1198, 10.1135/cccc2011105 .
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Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Klepetarova, Blanka;
Janeba, Zlatko;
Brehova, Petra;
Spacek, Petr, Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-Triazol-1-Yl) Methyl]uracils through the "click" protocol. Collect. Czech. Chem. Commun. 2011, 76(9), 1121 - 1131, 10.1135/cccc2011074 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Kaiser, Martin Maxmilian, A novel type of acyclic nucleoside phosphonates derived from 2-(phosphonomethoxy)propanoic acid. Tetrahedron 2012, 68(21), 4003 - 4012, 10.1016/j.tet.2012.03.066 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Baszczynski, Ondrej;
Prochazkova, Eliska, Microwave-assisted hydrolysis of phosphonate diesters: An efficient protocol for the preparation of phosphonic acids. Green Chemistry 2012, 14(8), 2282 - 2288, 10.1039/c2gc35547g .
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Krecmerova, Marcela;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Neyts, Johan;
Kasicka, Vaclav;
Stepan, George;
Sazelova, Petra;
Auwerx, Joeri;
Kiss, Eleonora;
Goris, Nesya, 9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro. Bioorganic and Medicinal Chemistry 2013, 21(5), 1199 - 1208, 10.1016/j.bmc.2012.12.044 .
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Dracinsky, Martin;
Cesnek, Michal;
Krystof, Vladimir;
Janeba, Zlatko;
Doleckova, Iva;
Brynda, Jiri;
Voller, Jiri, Synthesis and biological evaluation of guanidino analogues of roscovitine. European Journal of Medicinal Chemistry 2013, 62, 443 - 452, 10.1016/j.ejmech.2013.01.021 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Cechova, Lucie, A conversion of aromatic thiocyanates into sulfothioates: New synthetic route to aromatic Bunte salts. RSC Advances 2013, 3(8), 2650 - 2654, 10.1039/c2ra21975a .
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Dracinsky, Martin;
Janeba, Zlatko;
Cechova, Lucie;
Prochazkova, Eliska, A switchable intramolecular hydrogen bond in polysubstituted 5-nitrosopyrimidines. Journal of Organic Chemistry 2013, 78(20), 10121 - 10133, 10.1021/jo401441z .
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Cisarova, Ivana;
Dracinsky, Martin;
Kotora, Martin;
Jankova, Stepanka, Synthesis and rearrangement of dewar benzenes into biaryls: Experimental evidence for conrotatory ring opening. European Journal of Organic Chemistry 2008(1), 47 - 51, 10.1002/ejoc.200700916 .
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Dracinsky, Martin;
Kotora, Martin;
Eignerova, Barbara, Perfluoroalkylation through cross-metathesis between alkenes and (perfluoroalkyl)propenes. European Journal of Organic Chemistry 2008(26), 4493 - 4499, 10.1002/ejoc.200800230 .
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Budesinsky, Milos;
Dracinsky, Martin;
Kotora, Martin;
Klepetarova, Blanka;
Eignerova, Barbara;
Slavikova, Barbora;
St'Astna, Eva, Synthesis of fluorinated brassinosteroids based on alkene cross-metathesis and preliminary biological assessment. Journal of Medicinal Chemistry 2009, 52(18), 5753 - 5757, 10.1021/jm900495f .
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Dracinsky, Martin;
Kotora, Martin;
Castano, Obis;
Bour, Petr, Rearrangement of dewar benzene derivatives studied by DFT. Journal of Organic Chemistry 2010, 75(3), 576 - 581, 10.1021/jo902065n .
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Dracinsky, Martin;
Kotora, Martin;
Eignerova, Barbara;
Janouek, Zbynk, Synthesis of perfluoroalkylated carboranes by cross-metathesis of allylcarboranes and perfluoroalkylpropenes. Synlett 2010(6), 885 - 888, 10.1055/s-0029-1219546 .
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Dracinsky, Martin;
Kotora, Martin;
Eignerova, Barbara;
Bartunek, Petr;
Sedlak, David, Synthesis and biochemical characterization of a series of 17α-perfluoroalkylated estradiols as selective ligands for estrogen receptor α. Journal of Medicinal Chemistry 2010, 53(19), 6947 - 6953, 10.1021/jm100563h .
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Dracinsky, Martin;
Kotora, Martin;
Eignerova, Barbara;
Janousek, Zbynek;
Bartunek, Petr;
Sedlak, David, Synthesis and evaluation of 17α-(carboranylalkyl)estradiols as ligands for estrogen receptors α and β. Journal of Organometallic Chemistry 2013, 747, 178 - 183, 10.1016/j.jorganchem.2013.06.013 .
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Krecmerova, Marcela;
Dracinsky, Martin;
Votruba, Ivan;
Otmar, Miroslav;
Marak, David, 8-Aza-7,9-dideazaxanthine acyclic nucleoside phosphonate inhibitors of thymidine phosphorylase. Bioorganic and Medicinal Chemistry Letters 2011, 21(2), 652 - 654, 10.1016/j.bmcl.2010.12.027 .
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Krecmerova, Marcela;
Dracinsky, Martin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Tichy, Tomas, Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety. Eur. J. Med. Chem. 2012, 55, 307 - 314,8, 10.1016/j.ejmech.2012.07.027 .
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Dracinsky, Martin;
Pohl, Radek;
Rosenberg, Ivan;
Kovackova, Sona;
Rejman, Dominik;
Fiedler, Pavel, A convenient, high-yield synthesis of 1-substituted uracil and thymine derivatives. Tetrahedron 2009, 65(41), 8513 - 8523, 10.1016/j.tet.2009.08.019 .
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