Werner, Lukas
Articles
Machara, Ales;
Werner, Lukas;
Hudlicky, Tomas, Short chemoenzymatic azide-free synthesis of oseltamivir (tamiflu): Approaching the potential for process efficiency. Advanced Synthesis and Catalysis 2010, 352(1), 195 - 200, 10.1002/adsc.200900844 
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Machara, Ales;
Werner, Lukas;
Hudlicky, Tomas;
Adams, David R.;
Cox, D. Phillip, Synthesis of buprenorphine from oripavine via N-demethylation of oripavine quaternary salts. Journal of Organic Chemistry 2011, 76(11), 4628 - 4634, 10.1021/jo200567n .
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Machara, Ales;
Werner, Lukas;
Hudlicky, Tomas;
Adams, David R.;
Sullivan, Bradford;
Carrera, Ignacio;
Moser, Michael;
Andraos, John, Several generations of chemoenzymatic synthesis of oseltamivir (Tamiflu): Evolution of strategy, quest for a process-quality synthesis, and evaluation of efficiency metrics. Journal of Organic Chemistry 2011, 76(24), 10050 - 10067, 10.1021/jo2018872 .
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Machara, Ales;
Werner, Lukas;
Hudlicky, Tomas;
Cox, D. Phillip;
Endoma-Arias, Mary Ann, Improved synthesis of buprenorphine from thebaine and/or oripavine via palladium-catalyzed N-demethylation/acylation and/or concomitant O-demethylation. Advanced Synthesis and Catalysis 2012, 354(4), 613 - 626, 10.1002/adsc.201100807 .
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Machara, Ales;
Werner, Lukas;
Hudlicky, Tomas;
Adams, David R.;
Cox, D. Phillip;
Endoma-Arias, Mary Ann;
Wernerova, Martina;
Duchek, Jan, Unexpected N-demethylation of oxymorphone and oxycodone N-oxides mediated by the burgess reagent: Direct synthesis of naltrexone, naloxone, and other antagonists from oxymorphone. Advanced Synthesis and Catalysis 2012, 354(14-15), 2706 - 2712, 10.1002/adsc.201200676 .
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Patents
Machara, Ales;
Werner, Lukas;
Hudlicky, Tomas;
Adams, David R.;
CARROLL, Robert;
LEISCH, Hannes, PROCESSES FOR THE PREPARATION OF MORPHINANE AND MORPHINONE COMPOUNDS, WO2010/121369, 2010.