Friedman, Fred K.
Articles
Michl, Josef;
Brandt-Rauf, Paul;
Pincus, Matthew R.;
Scharf, Bruce;
Schmidt, Anna;
Huynh, Chan;
Hannan, Raquibul;
Von Gizycki, Hans;
Friedman, Fred K.;
Fine, Robert L., PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo. International Journal of Cancer 2006, 119(7), 1577 - 1585, 10.1002/ijc.22029 
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Michl, Josef;
Adler, Victor;
Pincus, Matthew R.;
Friedman, Fred K.;
Bowne, Wilbur;
Kamran, Ikram;
Chin, Edwin;
Zenilman, Michael, Two peptides derived from ras-p21 induce either phenotypic reversion or tumor cell necrosis of ras-transformed human cancer cells. Cancer Chemotherapy and Pharmacology 2008, 62(3), 491 - 498, 10.1007/s00280-007-0630-5 .
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Michl, Josef;
Adler, Victor;
Sookraj, Kelley A.;
Pincus, Matthew R.;
Qu, Yongxia;
Pestka, Sidney;
Izotova, Lara;
Friedman, Fred K.;
Bowne, Wilbur;
Zenilman, Michael;
Ikram, Kamran, Site-specific phosphorylation of raf in cells containing oncogenic ras-p21 is likely mediated by jun-N-terminal kinase. Annals of Clinical and Laboratory Science 2008, 38(1), 47 - 56.
Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Fine, Robert L.;
Brandt-Rauf, Paul W.;
Do, Tamara N.;
Rosal, Ramon V.;
Drew, Lisa;
Raffo, Anthony J.;
Petrylak, Daniel P.;
Cassai, Nicholas;
Szmulewicz, Joseph;
Sidhu, Gurdip, Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site. Oncogene 2003, 22(10), 1431 - 1444, 10.1038/sj.onc.1206258 .
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Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Kanovsky, Mecheal;
Botzolaki, Georgia;
Morin, Joseph;
Kovac, Cecilia;
Chung, Denise L.;
Chie, Lyndon, Peptides designed from molecular modeling studies of the ras-p21 protein induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth. Cancer Chemotherapy and Pharmacology 2003, 52(3), 202 - 208, 10.1007/s00280-003-0639-3 .
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Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Brandt-Rauf, Paul W.;
Kanovsky, Mecheal;
Chie, Lyndon;
Smith, Steven;
Ranginwale, Masood;
Flom, Judy;
Chung, Denise;
Robinson, Richard C.;
Yamaizumi, Ziro, Differences in patterns of activation of MAP kinase induced by oncogenic ras-p21 and insulin in oocytes. Experimental Cell Research 2001, 269(1), 162 - 169, 10.1006/excr.2001.5311 .
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Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Fine, Robert L.;
Brandt-Rauf, Paul W.;
Rosal, Ramon;
Drew, Lisa;
Kanovsky, Mecheal;
Raffo, Anthony;
Do, Tamara;
Rubinstein, Pablo;
Visser, Jan;
Robinson, Richard, Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells. Proceedings of the National Academy of Sciences of the United States of America 2001, 98(22), 12438 - 12443, 10.1073/pnas.211280698 .
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Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Brandt-Rauf, Paul W.;
Morin, Joseph;
Kovac, Cecilia;
Chung, Denise L.;
Chie, Lyndon;
Flom, Judy;
Yamaizumi, Ziro;
Robinson, Richard;
Kovac;
Chie;
Morin;
Friedman;
Robinson;
Chung;
Kanovsky;
Kanovsky, Mechael;
Flom;
Brandt-Rauf;
Yamaizumi;
Michl;
Pincus, Plasmid expression of a peptide that selectively blocks oncogenic ras-p21-induced oocyte maturation. Cancer Chemotherapy and Pharmacology 2001, 48(1), 9 - 14, 10.1007/s002800100288 .
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Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Brandt-Rauf, Paul W.;
Chung, Denise L.;
Chie, Lyndon;
Yamaizumi;
Chen, James M.;
Amar, Shazia, Inhibition of oncogenic and activated wild-type ras-p21 protein-induced oocyte maturation by peptides from the guanine-nucleotide exchange protein, SOS, identified from molecular dynamics calculations. Selective inhibition of oncogenic ras-p21. Journal of Protein Chemistry 1999, 18(8), 875 - 879.
Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Brandt-Rauf, Paul W.;
Chung, Denise L.;
Chie, Lyndon;
Yamaizumi;
Chen, James M.;
Amar, Shazia, Identification of the site of inhibition of oncogenic ras-p21-induced signal transduction by a peptide from a ras effector domain. Journal of Protein Chemistry 1999, 18(8), 881 - 884.
Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Chung, Denise L.;
Chie, Lyndon;
Yamaizumi;
Chen, James M.;
Amar, Shazia;
Brandt-Kauf, Paul W., Inhibition of OncogenicActivated Wild-Type ras-p21 Protein-Induced Oocyte Maturation by Peptides from the Guanine-Nucleotide Exchange Protein, SOS, Identified from Molecular Dynamics Calculations. Selective Inhibition of Oncogenic ras-p21. Protein Journal 1999, 18(8), 875 - 879.
Michl, Josef;
Pincus, Matthew R.;
Friedman, Fred K.;
Chung, Denise L.;
Chie, Lyndon;
Yamaizumi;
Chen, James M.;
Amar, Shazia;
Brandt-Kauf, Paul W., Identification of the Site of Inhibition of Oncogenic ras-p21 -Induced Signal Transduction by a Peptide from a ras Effector Domain. Protein Journal 1999, 18(8), 881 - 884.