Smrcina, Martin

Compounds

Kocovsky, Pavel; Pour, Milan; Gogoll, Adolf; Hanus, Vladimir; Smrcina, Martin, Corner attack on cyclopropane by thallium (III) ions. A highly stereospecific cleavage and skeletal rearrangement of 3α,5-cyclo-5α-cholestan-6α-ol. Journal of the American Chemical Society 1990, 112(18), 6735 - 6737.

Kocovsky, Pavel; Hanus, Vladimir; Smrcina, Martin; Lorenc, Miroslav; Sedmera, Petr, Synthesis of Enantiomerically Pure 2,2'-Dihydroxy-1,1'-binaphthyl, 2,2'-Diamino-1,1'-binaphthyl, and 2-Amino-2'-hydroxy-1,1'-binaphthyl. Comparison of Processes Operating as Diastereoselective Crystallization and as Second-Order Asymmetric Transformation. Journal of Organic Chemistry 1992, 57(6), 1917 - 1920, 10.1021/jo00032a055

Polakova, Jana; Kocovsky, Pavel; Vyskocil, Stepan; Smrcina, Martin, Synthesis of Enantiomerically Pure Binaphthyl Derivatives. Mechanism of the Enantioselective, Oxidative Coupling of Naphthols and Designing a Catalytic Cycle. Journal of Organic Chemistry 1993, 58(17), 4534 - 4538, 10.1021/jo00069a010

et al.; Polasek, Miroslav; Vyskocil, Stepan; Smrcina, Martin; Maca, Bohumil; Claxton, Thomas A., Selective Cross-Coupling of 2-Naphthol and 2-Naphthylamine Derivatives. A Facile Synthesis of 2,2',3-Trisubstituted and 2,2',3,3'-Tetrasubstituted 1,1'-Binaphthyls. Journal of Organic Chemistry 1994, 59(8), 2156 - 2163, 10.1021/jo00087a036

Kocovsky, Pavel; Langer, Vratislav; Polasek, Miroslav; Vyskocil, Stepan; Smrcina, Martin; Claxton, Thomas A.; Hanues, Vladimir; Chew, Benjamin G. M.; Zax, David B.; Verrier, Hugh; Harper, Kevin, The S2 reaction in the solid state. An unusual, B2 aminolysis of an ester group in crystalline (±)-2-amino-2′-hydroxy-3′-(methoxycarbonyl)-1,1′- binaphthyl elucidated by X-ray diffraction and isotopic labeling. New experimental evidence for linearity in S2 substitution. Journal of the American Chemical Society 1996, 118(2), 487 - 488.

Polakova, Jana; Kocovsky, Pavel; Vyskocil, Stepan; Smrcina, Martin; Polivkova, Jana, Synthesis and resolution of racemic 2-amino-2′-hydroxy-1,1′-binaphthyl. Collect. Czech. Chem. Commun. 1996, 61(10), 1520 - 1524, 10.1135/cccc19961520

Polakova, Jana; Kocovsky, Pavel; Polasek, Miroslav; Vyskocil, Stepan; Hanus, Vladimir; Smrcina, Martin; Verrier, Hugh; Polivkova, Jana; Sejbal, Jan, Axially chiral 1,1''-binaphthyls with non-identical groups in 2,2'-positions. Synthesis of the enantiomerically pure 2-hydroxy-2'-thiol and substituted 2-amino-2'-thiols. Tetrahedron Asymmetry 1997, 8(4), 537 - 546, 10.1016/S0957-4166(96)00539-3

Majerova, Eva; Smrcina, Martin; Majer, Pavel; Guerassina, Tatiana A.; Eissenstat, Michael A., Facile stereoselective synthesis of γ-substituted γ-amino acids from the corresponding α-amino acids. Tetrahedron 1997, 53(38), 12867 - 12874, 10.1016/S0040-4020(97)00840-5

Kocovsky, Pavel; Vyskocil, Stepan; Smrcina, Martin, A facile synthesis of the enantiopure, nitrogen-substituted 2,2′-diamino-1,1′-binaphthyls as potential ligands for catalytic asymmetric reactions. Collect. Czech. Chem. Commun. 1998, 63(4), 515 - 519.

Kocovsky, Pavel; Vyskocil, Stepan; Smrcina, Martin, Synthesis of 2-amino-2'-diphenylphosphino-1,1'-binaphthyl (MAP) and its accelerating effect on the Pd(0)-catalyzed N-arylation. Tetrahedron Letters 1998, 39(50), 9289 - 9292.

Sticha, Martin; Kocovsky, Pavel; Hanus, Vladimir; Smrcina, Martin; Vyskocil, Stepn; Jaracz, Stanislav; Miroslav Poldsek, Synthesis of N-Alkylated and N-Arylated Derivatives of 2-Amino-2′-hydroxy-l, 1′-binaphthyl (NOBIN) and 2,2′-Diamino-1, 1′'-binaphthyl and Their Application in the Enantioselective Addition of Diethylzinc to Aromatic Aldehydes a. Journal of Organic Chemistry 1998, 63(22), 7727 - 7737.

Kocovsky, Pavel; Polasek, Miroslav; Vyskocil, Stepan; Hanus, Vladimir; Smrcina, Martin, Derivatives of 2-amino-2′-diphenylphosphino-1,1′-binaphthyl (MAP) and their application in asymmetric palladium(O) -catalyzed allylic substitution. Journal of Organic Chemistry 1998, 63(22), 7738 - 7748.

Turecek, Frantisek; Smrcina, Martin; Mayer, Philip S.; Lee, Hak-No; Scheidemann, Adi A.; Olney, Terry N.; Schumacher, Frank; Strop, Petr; Patek, Marcel; Schirlin, Daniel, Preparative separation of mixtures by mass spectrometry. Analytical Chemistry 2005, 77(14), 4378 - 4384, 10.1021/ac050444j

Smrcina, Martin; Patek, Marcel; Safar, Pavel; Wegrzyniak, Eric; Bjergarde, Kirsten; Weichsel, Aleksandra; Strop, Peter, 2D and 3D Spatially Addressed Arrays for High-Throughput Automated Synthesis of Combinatorial Libraries. Journal of Combinatorial Chemistry 2004, 6(1), 43 - 49, 10.1021/cc0300311

Kocovsky, Pavel; Vyskocil, Stepan; Smrcina, Martin, Non-symmetrically substituted 1,1′-binaphthyls in enantioselective catalysis. Chemical Reviews 2003, 103(8), 3213 - 3245, 10.1021/cr9900230

Smrcina, Martin; Patek, Marcel; Nakanishi, Eiji; Izawa, Hiroyuki, Solid-phase synthesis of substituted guanidines using a novel acid labile linker. Journal of Combinatorial Chemistry 2000, 2(4), 370 - 377.

Patents

Smrcina, Martin; Patek, Marcel; Weichsel, Aleksandra; Weichert, Andreas; Strobel, Hartmut; Wohlfart, Paulus, Triaza- and tetraaza-anthracenedione derivates, their preparation and their use as pharmaceuticals, EP1471066, 2004.

Smrcina, Martin; Patek, Marcel; Bjergarde, Kirsten; STEINHAGEN, Henning; WEI, Linli; HUBER, Jochen; RITTER, Kurt; PIRARD, Bernard, PYRAZOLOPYRIDINE DERIVATIVES AS INHIBITORS OF BETA-ADRENERGIC RECEPTOR KINASE 1, WO2007/241, 2007.

Smrcina, Martin; Patek, Marcel; BJERGARDE, Kristen; BACQUE, Eric; RONAN, Baptiste; SOUAILLE, Catherine; VIVIANI, Fabrice; TABART, Michel; LEROY, Vincent; ACKERMAN-BERRIER, Martha; NAIR, Anil; DODSON, Mark, 7-SUBSTITUTED AZA-INDAZOLES, COMPOSITIONS CONTAINING SAME, PRODUCTION METHOD AND USE THEREOF, WO2007/17577, 2007.

Smrcina, Martin; PEDGRIFT, Brian; RAMOS, Antonio D.; THORPE, David S.; WIRE, William; ROSSE, Gerard; ZHAO, Jianhong; CLEMENS, Jennifer; LE, Tieu-Binh; JOHN, Stanly; FREED, Brian S.; FRANCIS, Robert S.; CAULFIELD, Thomas, J., SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS, WO2008/151211, 2008.

Smrcina, Martin; FORICHER, Yann; WEBER, Fabienne; VAN DORSSELAER, Viviane, PYRAZOLE 3,5 CARBOXYLATE DERIVATIVES PREPARATION AND THERAPEUTIC APPLICATION THEREOF, WO2009/27601, 2009.

Smrcina, Martin; THORPE, David S.; CABEL, Dagmar D., INHIBITORS OF THE CHEMOKINE RECEPTOR CXCR3, WO2009/105435, 2009.

Smrcina, Martin; FORICHER, Yann; WEBER, Fabienne; VAN DORSSELAER, Viviane, DERIVATIVES OF PYRAZOLE 3,5-CARBOXYLATES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS, US2010/160377, 2010.

Smrcina, Martin; Safar, Pavel; LENNIG, Petra; STENGELIN, Siegfried; KLABUNDE, Thomas; GOSSEL, Matthias; SPOONAMORE, James; MERRIMAN, Gregory; KLEIN, Joseph, T.; WHITELEY, Brian; LANTER, Carolina; BORDEAU, Kenneth; YANG, Zhaoxia, HEXAHYDRO-PYRAZINO[1,2-A]PYRIMIDINE-4, 7-DIONE DERIVATIVES SUBSTITUTED WITH AMINO ACIDS, WO2006/24390, 2006.

Ë; B; Smrcina, Martin; Patek, Marcel; Weichsel, Aleksandra; BATA, Imre; BUDZER-LANTOS, P; ter; VASAS, Attila; BART; Á; N; BODOR, Veronika; FERENCZY, Gy; ö; rgy; T; M; SK; ZI, Zsuzsanna; SZELECZKY, G; bor; TORI, S; ndor; S.THORPE, David, CYCLOALKANE CARBOXYLIC ACID DERIVATIVES AS CXCR3 RECEPTOR ANTAGONISTS, WO2013/84013, 2013.