Cesnek, Michal

Dvorak, Dalimil;
Havelkova, Martina;
Hocek, Michal;
Cesnek, Michal, The Suzuki-Miyaura cross-coupling reactions of 6-halopurines with boronic acids leading to 6-aryl- and 6-alkenylpurines. Synlett 1999(7), 1145 - 1147.
Holy, Antonin;
Hocek, Michal;
Cesnek, Michal, Synthesis of acyclic nucleotide analogues derived from 2-amino-6-C-substituted purines via cross-coupling reactions of 2-amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with diverse organometallic reagents. Collect. Czech. Chem. Commun. 2000, 65(8), 1357 - 1373.
Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena, 6-Guanidinopurine nucleosides and their analogues. Tetrahedron 2002, 58(15), 2985 - 2996, 10.1016/S0040-4020(02)00186-2
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Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena, New 2-alkynyl derivatives of the acyclic nucleoside 9-(2,3-dihydroxypropyl) adenine and their 6-guanidinopurine counterparts as potential effectors of adenosine receptors. Collect. Czech. Chem. Commun. 2003, 68(11), 2201 - 2218, 10.1135/cccc20032201
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Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena;
Zidek, Zdenek, Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6- guanidinopurines and their influence on the NO-production in macrophages. Bioorganic and Medicinal Chemistry 2005, 13(8), 2917 - 2926, 10.1016/j.bmc.2005.02.008
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Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena;
Solinova, Veronika;
Koval, Dusan;
Kasicka, Vaclav, Synthesis and properties of 2-guanidinopurines. Collect. Czech. Chem. Commun. 2006, 71(9), 1303 - 1319, 10.1135/cccc20061303
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Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena;
Zidek, Zdenek;
Kmonickova, Eva, Synthesis of guanidino analogues of PMPDAP and their immunobiological activity. Bioorganic and Medicinal Chemistry 2008, 16(2), 965 - 980, 10.1016/j.bmc.2007.10.010
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Cesnek, Michal;
Janeba, Zlatko;
Baszczynski, Ondrej, Efficient and 'green' microwave-assisted synthesis of haloalkylphosphonates via the Michaelis-Arbuzov reaction. Green Chemistry 2011, 13(4), 882 - 888, 10.1039/c0gc00509f
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Krecmerova, Marcela;
Holy, Antonin;
Cesnek, Michal;
Hockova, Dana;
Naesens, Lieve;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Brereton, Ian M.;
Winzor, Donald J., Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: A target for anti-malarial chemotherapy. Molecular and Biochemical Parasitology 2010, 173(2), 165 - 169, 10.1016/j.molbiopara.2010.05.018
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Holy, Antonin;
Dracinsky, Martin;
Cesnek, Michal;
Janeba, Zlatko;
Brehova, Petra, The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling reaction. Tetrahedron 2011, 67(38), 7379 - 7385, 10.1016/j.tet.2011.07.040
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Holy, Antonin;
Dracinsky, Martin;
Cesnek, Michal;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W.;
Jersey, John de;
Baszczynski, Ondrej, Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. Bioorganic and Medicinal Chemistry 2012, 20(2), 1076 - 1089, 10.1016/j.bmc.2011.11.034
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Holy, Antonin;
Cesnek, Michal;
Solinova, Veronika;
Koval, Dusan;
Kasicka, Vaclav, Determination of acid-base dissociation constants of amino- and guanidinopurine nucleotide analogs and related compounds by capillary zone electrophoresis. Electrophoresis 2006, 27(5-6), 1006 - 1019, 10.1002/elps.200500815
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Holy, Antonin;
Cesnek, Michal;
Jacobson, Kenneth A.;
Ohno, Michihiro;
Duong, Heng T.;
Kim, Soo-Kyung;
Tchilibon, Susanna;
Gao, Zhan-Guo, A neoceptor approach to unraveling microscopic interactions between the human A adenosine receptor and its agonists. Chemistry and Biology 2005, 12(2), 237 - 247, 10.1016/j.chembiol.2004.12.010
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Dracinsky, Martin;
Cesnek, Michal;
Krystof, Vladimir;
Janeba, Zlatko;
Doleckova, Iva;
Brynda, Jiri;
Voller, Jiri, Synthesis and biological evaluation of guanidino analogues of roscovitine. European Journal of Medicinal Chemistry 2013, 62, 443 - 452, 10.1016/j.ejmech.2013.01.021
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Cesnek, Michal;
Janeba, Zlatko;
Trejtnar, Frantisek;
Pavek, Petr;
Mandikova, Jana;
Volkova, Marie;
Kubicek, Vladimir, Interactions with selected drug renal transporters and transporter-mediated cytotoxicity in antiviral agents from the group of acyclic nucleoside phosphonates. Toxicology 2013, 311(3), 135 - 146, 10.1016/j.tox.2013.07.004
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Cesnek, Michal;
Smidkova, Marketa;
Tloust'Ova, Eva;
Janeba, Zlatko;
Mertlikova-Kaiserova, Helena;
Dvorakova, Alexandra, Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis. Antimicrobial Agents and Chemotherapy 2014, 58(2), 664 - 671, 10.1128/AAC.01685-13
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