Hockova, Dana
Articles
Dvorakova, Hana;
Hocek, Michal;
Votruba, Ivan;
Hockova, Dana, Synthesis and cytostatic activity of nucleosides and acyclic nucleoside analogues derived from 6-(trifluoromethyl)purines. Tetrahedron 1999, 55(36), 11109 - 11118, 10.1016/S0040-4020(99)00615-8 
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Hocek, Michal;
Hockova, Dana;
Stambasky, Jan, Cytostatic 6-arylpurine nucleosides V. synthesis of 8-substituted 6-phenylpurine ribonucleosides. Collect. Czech. Chem. Commun. 2003, 68(5), 837 - 848, 10.1135/cccc20030837 .
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Dvorakova, Hana;
Hocek, Michal;
Hockova, Dana, Dichotomy in regioselective cross-coupling reactions of 6,8-dichloropurines with phenylboronic acid and methylmagnesium chloride: Synthesis of 6,8-di-substituted purines. Synthesis 2004(6), 889 - 894.
Hocek, Michal;
Hockova, Dana;
Seckarova, Pavlina;
Marek, Radek;
Malinakova, Katerina;
Kolehmainen, Erkki;
Sklenar, Vladimir, Direct determination of tautomerism in purine derivatives by low-temperature NMR spectroscopy. Tetrahedron Letters 2004, 45(33), 6259 - 6263, 10.1016/j.tetlet.2004.06.088 .
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Holy, Antonin;
et al.;
Dvorakova, Hana;
Votruba, Ivan;
Hockova, Dana;
Guenter, Jaroslav, SYNTHESIS OF 2-DEOXY-β-D-RIBONUCLEOSIDES AND2,3-DIDEOXY.β-D-PENTOFURANOSIDES ON IMMOBILIZED BACTERIAL CELLS. Collect. Czech. Chem. Commun. 1994, 59(10), 2303 - 2330, 10.1135/cccc19942303 .
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Budesinsky, Milos;
Holy, Antonin;
Masojidkova, Milena;
Hockova, Dana, ACYCLIC NUCLEOSIDE AND NUCLEOTIDE ANALOGS DERIVED FROM 2-AZAADENINE. Collect. Czech. Chem. Commun. 1995, 60(2), 224 - 236, 10.1135/cccc19950224 .
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Holy, Antonin;
Hockova, Dana;
Votavova, Hana, Synthesis and Chiroptical Properties of Some Abbreviated NAD Analogues. Tetrahedron Asymmetry 1995, 6(9), 2375 - 2384, 10.1016/0957-4166(95)00315-G .
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Holy, Antonin;
Masojidkova, Milena;
Hockova, Dana, "Abbreviated" NADanalogues containing a phosphonate function. Collect. Czech. Chem. Commun. 1996, 61(10), 1538 - 1548, 10.1135/cccc19961538 .
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Holy, Antonin;
Hockova, Dana, "Abbreviated" NAD Analogues Containing a Phosphonate Function. Collect. Czech. Chem. Commun. 1996, 61, S52 - S54.
Holy, Antonin;
Hockova, Dana, Synthesis of some "abbreviated" NAD analogues. Collect. Czech. Chem. Commun. 1997, 62(6), 948 - 956.
Budesinsky, Milos;
Holy, Antonin;
Hockova, Dana;
Marek, Radek;
Marek, Jaromir, Regioselective preparation of N- and N-alkyl derivatives of N- [(dimethylamino)methylene]adenine bearing an active methylene group and their further derivatization leading to α-branched acyclic nucleoside analogues. European Journal of Organic Chemistry 1999(10), 2675 - 2682.
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana, 5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy) ethoxy]pyrimidines-Acyclic Nucleoside Phosphonate Analogues with Antiviral Activity. Journal of Medicinal Chemistry 2003, 46(23), 5064 - 5073.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Hockova, Dana, An efficient synthesis of cytostatic mono and bis-alkynylpyrimidine derivatives by the Sonogashira cross-coupling reactions of 2,4-diamino-6- iodopyrimidine and 2-amino-4,6-dichloropyrimidine. Tetrahedron 2004, 60(23), 4983 - 4987, 10.1016/j.tet.2004.04.035 .
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Holy, Antonin;
Masojidkova, Milena;
Hockova, Dana, Sonogashira cross-coupling in the synthesis of acyclic nucleoside phosphonates: Preparation of 6-[(phosphonomethoxy)alkynyl]- and 6-[(phosphonomethoxy)alkyl]pyrimidines. Collect. Czech. Chem. Commun. 2005, 70(2), 247 - 258, 10.1135/cccc20050247 .
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Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana, Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2- (phosphonomethoxy)ethoxy]pyrimidine and related compounds. Bioorganic and Medicinal Chemistry 2004, 12(12), 3197 - 3202, 10.1016/j.bmc.2004.04.002 .
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Holy, Antonin;
Hockova, Dana;
Keough, Dianne T.;
Naesens, Lieve M. J.;
Skinner-Adams, Tina S.;
De Jersey, John;
Guddat, Luke W., Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutics. Journal of Medicinal Chemistry 2009, 52(14), 4391 - 4399, 10.1021/jm900267n .
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Holy, Antonin;
Dracinsky, Martin;
Hockova, Dana, Synthesis and properties of a novel type of acyclic nucleoside phosphonates: 2-(purin-9-yl)ethoxyphenylphosphonic acids. European Journal of Organic Chemistry 2010(15), 2885 - 2892, 10.1002/ejoc.201000061 .
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Holy, Antonin;
Masojidkova, Milena;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W.;
Jersey, John de, Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase. Bioorganic and Medicinal Chemistry 2009, 17(17), 6218 - 6232, 10.1016/j.bmc.2009.07.044 .
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Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Hockova, Dana, Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activity. Bioorganic and Medicinal Chemistry 2011, 19(15), 4445 - 4453, 10.1016/j.bmc.2011.06.045 .
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Krecmerova, Marcela;
Holy, Antonin;
Cesnek, Michal;
Hockova, Dana;
Naesens, Lieve;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Brereton, Ian M.;
Winzor, Donald J., Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: A target for anti-malarial chemotherapy. Molecular and Biochemical Parasitology 2010, 173(2), 165 - 169, 10.1016/j.molbiopara.2010.05.018 .
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Holy, Antonin;
Dracinsky, Martin;
Cesnek, Michal;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W.;
Jersey, John de;
Baszczynski, Ondrej, Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. Bioorganic and Medicinal Chemistry 2012, 20(2), 1076 - 1089, 10.1016/j.bmc.2011.11.034 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W., Synthesis of purine N-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents. Bioorganic and Medicinal Chemistry 2012, 20(3), 1222 - 1230, 10.1016/j.bmc.2011.12.034 .
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Holy, Antonin;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana;
Schols, Dominique;
Van Laethem, Kristel;
Masojidkova, Milina, Pronounced in vitro and in vivo antiretroviral activity of 5-substituted 2,4-diamino-6-[2-(phosphonomethoxy)ethoxy] pyrimidines. Journal of Antimicrobial Chemotherapy 2007, 59(1), 80 - 86, 10.1093/jac/dkl454 .
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Holy, Antonin;
Hockova, Dana;
Naesens, Lieve;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W., 6-oxopurine phosphoribosyltransferase: A target for the development of antimalarial drugs. Current Topics in Medicinal Chemistry 2011, 11(16), 2085 - 2102, 10.2174/156802611796575911 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
Guddat, Luke W.;
Baszczynski, Ondrej, The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. European Journal of Medicinal Chemistry 2013, 67, 81 - 89, 10.1016/j.ejmech.2013.06.032 .
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Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Wang, Tzu-Hsuan, Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry 2012, 55(13), 6209 - 6223, 10.1021/jm300662d .
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Hockova, Dana;
Slavetinska, Lenka;
Janeba, Zlatko;
Naesens, Lieve;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Tichy, Tomas;
Spacek, Petr;
Wang, Tzu-Hsuan;
Edstein, Michael D.;
Chavchich, Marina, Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. Journal of Medicinal Chemistry 2013, 56(6), 2513 - 2526, 10.1021/jm301893b .
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Hockova, Dana;
Janeba, Zlatko, The role of acyclic nucleoside phosphonates as potential antimalarials. Chemicke Listy 2014, 108(4), 335 - 343.
Krecmerova, Marcela;
Hockova, Dana;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Rejman, Dominik;
Spacek, Petr;
Eng, Wai Soon;
Jans, Harmen;
West, Nicholas P.;
Naesens, Lieve M.J., Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: Potential for new antibacterial agents. Journal of Medicinal Chemistry 2013, 56(17), 6967 - 6984, 10.1021/jm400779n .
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