Otmar, Miroslav

Novak, Petr;
Kotora, Martin;
Hocek, Michal;
Cihalova, Sylva;
Otmar, Miroslav, Co- and homocyclotrimerization reactions of protected 1-alkynyl-2-deoxyribofuranose. Synthesis of C-nucleosides, C-di- and C-trisaccharide analogues. Tetrahedron 2008, 64(22), 5200 - 5207, 10.1016/j.tet.2008.03.046
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Holy, Antonin;
Masojidkova, Milena;
Otmar, Miroslav;
Rosenberg, Ivan, <5-(ADENIN-9-YL)-5-DEOXYPENTOFURANOSYL>PHOSPHONATES - A NOVEL TYPE NUCLEOTIDE ANALOGS RELATED TO HPMPA. I. DERIVATIVES WITH L-arabino, D-arabino, 2-DEOXY-L-erythro AND 2-DEOXY-L-threo CONFIGURATION. Collect. Czech. Chem. Commun. 1993, 58(9), 2159 - 2179, 10.1135/cccc19932159
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Holy, Antonin;
Masojidkova, Milena;
Otmar, Miroslav;
Rosenberg, Ivan, <5-(ADENIN-9-YL)-5-DEOXY-L-PENTOFURANOSYL>PHOSPHONATES - A NOVEL TYPE OF NUCLEOTIDE ANALOGS RELATED TO HPMPA. II. SYNTHESIS OF L-ribo and L-xylo CONFIGURATED DERIVATIVES BY RECYCLIZATION OF DIETHYL (5-RS)-<1,2-O-ISOPROPYLIDENE-5-O-METHANESULFONYL-D-PENTOFURANOS-5-C-YL>PHOSPHONATES .... Collect. Czech. Chem. Commun. 1993, 58(9), 2180 - 2196, 10.1135/cccc19932180
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Holy, Antonin;
Masojidkova, Milena;
Otmar, Miroslav, Two Synthetic Approaches to 9-Deaza Analogues of 9-(2,3-Dihydroxypropyl)adenine (DHPA). Collect. Czech. Chem. Commun. 1996, 61, S49 - S51.
Holy, Antonin;
Votruba, Ivan;
Otmar, Miroslav;
Birkus, Gabriel;
Kramata, Pavel, Structural Features of Acyclic Nucleotide Analogs Conferring Inhibitory Effects on Cellular Replicative DNA Polymerases. Collect. Czech. Chem. Commun. 1996, 61, S188 - S191.
Budesinsky, Milos;
Holy, Antonin;
Otmar, Miroslav;
Masojldkova, Milena, Catalytic hydrogenation causes C-benzyl bond cleavage in 6-amino-7,7-dibenzyl-2,4-dimethoxy-7H-pyrrolo[3,2-d]pyrimidine: An example indicating novel route to 6-amino-7-benzyl-5H-pyrrolo-[3,2-d]pyrimidines and related compounds. Tetrahedron 1998, 54(12), 2931 - 2940, 10.1016/S0040-4020(98)83028-7
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Holy, Antonin;
Votruba, Ivan;
Otmar, Miroslav;
Birkus, Gabriel;
Kramata, Pavel;
Otova, Berta, Nonproteolyzed form of DNA-polymerase ε from T-cell spontaneous lymphoma of Sprague-Dawley inbred rat: Isolation and characterization. Collect. Czech. Chem. Commun. 1998, 63(5), 723 - 731.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Otmar, Miroslav, An alternative synthesis of HPMPC and HPMPA diphosphoryl derivatives. Collect. Czech. Chem. Commun. 2001, 66(3), 500 - 506, 10.1135/cccc20010500
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Holy, Antonin;
Masojidkova, Milena;
Otmar, Miroslav;
Polakova, Lucie, A facile synthesis of azetidin-2-ylphosphonic acid and its 1-alkyl derivatives. Collect. Czech. Chem. Commun. 2001, 66(3), 507 - 516, 10.1135/cccc20010507
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Holy, Antonin;
Votruba, Ivan;
Otmar, Miroslav;
Birkus, Gabriel, Interactions of 1-[(S)-3-hydroxy-2-(phosphonomethoxy)-propyl]cytosine (cidofovir) diphosphate with DNA polymerases α, δ and ε*. Collect. Czech. Chem. Commun. 2001, 66(11), 1698 - 1706.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Capek, Petr;
Otmar, Miroslav, A facile synthesis of 9-deaza analogue of olomoucine. Collect. Czech. Chem. Commun. 2003, 68(4), 779 - 791, 10.1135/cccc20030779
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Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Otmar, Miroslav, Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9- deazapurine and related compounds. Bioorganic and Medicinal Chemistry 2004, 12(12), 3187 - 3195, 10.1016/j.bmc.2004.04.003
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Holy, Antonin;
Masojidkova, Milena;
Pohl, Radek;
Otmar, Miroslav;
Bambuch, Vitezslav, C-Functionalization of 9-deazapurines by cross-coupling reactions. Tetrahedron 2007, 63(7), 1589 - 1601, 10.1016/j.tet.2006.12.008
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Krecmerova, Marcela;
Holy, Antonin;
Jansa, Petr;
Otmar, Miroslav;
Baszczynski, Ondrej;
Blazek, Jiri;
Kaiser, Martin Maxmilian;
Drancinsky, Martin;
Kralova, Blanka, An enzymatic glycosylation of nucleoside analogues using β-galactosidase from Escherichia coli. Bioorganic and Medicinal Chemistry 2012, 20(9), 3111 - 3118, 10.1016/j.bmc.2012.02.062
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Holy, Antonin;
Votruba, Ivan;
Otmar, Miroslav;
Birkus, Gabriel;
Rosenberg, Ivan;
Rejman, Dominik, The substrate activity of (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine diphosphate toward DNA polymerases α, δ and ε. Antiviral Chemistry and Chemotherapy 2004, 15(1), 23 - 33.
Holy, Antonin;
Masojidkova, Milena;
Otmar, Miroslav, Reductive cyclization of 6-cyanomethyl-5-nitropyrimidines - An efficient route to 7-alkyl-5H-pyrrolo[3,2-d]pyrimidines and 6-amino-7,7-dialkyl-7H-pyrrolo[3,2-d]pyrimidines. Utilization in the synthesis of 9-deaza analogues of DHPA. Tetrahedron 1997, 53(1), 391 - 400, 10.1016/S0040-4020(96)00993-3
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Holy, Antonin;
Votruba, Ivan;
Otmar, Miroslav;
Rosenberg, Ivan;
Merta, Ales;
Travnicek, Miloslav;
Rebabecky, Hubert H., Inhibition of avian myeloblastosis virus reverse transcriptase by diphosphates of acyclic phosphonylmethyl nucleotide analogues. Antiviral Research 1990, 13(6), 287 - 293, 10.1016/0166-3542(90)90013-W
.

Holy, Antonin;
Votruba, Ivan;
Otmar, Miroslav;
Rosenberg, Ivan;
Hrebabecky, Hubert;
Merta, Ales;
Bernaerts, Ria, Inhibition of herpes simplex virus DNA polymerase by diphosphates of acyclic phosphonylmethoxyalkyl nucleotide analogues. Antiviral Research 1990, 13(5), 209 - 218, 10.1016/0166-3542(90)90066-G
.

Holy, Antonin;
Votruba, Ivan;
Otmar, Miroslav;
Rosenberg, Ivan;
Cerny, Jaroslav;
Vonka, Vladimir, Phosphonylmethyl ethers of acyclic nucleoside analogues: Inhibitors of HSV-1 induced ribonucleotide reductase. Antiviral Research 1990, 13(5), 253 - 263, 10.1016/0166-3542(90)90070-N
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Holy, Antonin;
Jindrich, Jindrich;
Votruba, Ivan;
Otmar, Miroslav;
Cihlar, Tomas;
Rosenberg, Ivan;
Merta, Ales;
Herve, Tchaou Y., Phosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP (dAMP) kinase from L1210 cells. Biochemical Pharmacology 1992, 44(10), 2067 - 2077, 10.1016/0006-2952(92)90110-5
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