Cihlar, Tomas
Articles
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Mackman, Richard;
Dzubak, Petr;
Hajduch, Marian;
Ameral, Ria;
Birkus, Gabriel;
Wang, Ting;
Ray, Adrian S.;
Cihlar, Tomas, 6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents. Journal of Medicinal Chemistry 2010, 53(1), 460 - 470, 10.1021/jm901428k 
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Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Ameral, Ria;
Birkus, Gabriel;
Cihlar, Tomas;
Spacilova, Pavla;
Snasel, Jan;
Zabranska, Helena;
Pichova, Iva, CycloSal-phosphate pronucleotides of cytostatic 6-(het)aryl-7-deazapurine ribonucleosides: Synthesis, cytostatic activity, and inhibition of adenosine kinases. ChemMedChem 2010, 5(8), 1386 - 1396, 10.1002/cmdc.201000192 .
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Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Birkus, Gabriel;
Cihlar, Tomas;
Perlikova, Pavla;
Shih, Robert, Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides. Bioorganic and Medicinal Chemistry 2011, 19(1), 229 - 242, 10.1016/j.bmc.2010.11.029 .
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Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Dzubak, Petr;
Hajduch, Marian;
Birkus, Gabriel;
Wang, Ting;
Ray, Adrian S.;
Cihlar, Tomas;
Pichova, Iva;
Perlikova, Pavla;
Bourderioux, Aurelie;
Konecny, Petr;
Stray, Kirsten M.;
Feng, Joy Y., Synthesis and significant cytostatic activity of 7-hetaryl-7- deazaadenosines. Journal of Medicinal Chemistry 2011, 54(15), 5498 - 5507, 10.1021/jm2005173 .
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Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Slavetinska, Lenka;
Birkus, Gabriel;
Cihlar, Tomas;
Perlikova, Pavla;
Bourderioux, Aurelie;
Bahador, Gina, Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′- fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic and Medicinal Chemistry 2012, 20(17), 5202 - 5214, 10.1016/j.bmc.2012.07.003 .
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Holy, Antonin;
Votruba, Ivan;
Cihlar, Tomas;
Rosenberg, Ivan;
Horska, Kvetoslava;
Liboska, Radek, METABOLISM OF 1-(S)-(3-HYDROXY-2-PHOSPHONOMETHOXYPROPYL)CYTOSINE (HPMPC) IN HUMAN EMBRYONIC LUNG CELLS. Collect. Czech. Chem. Commun. 1992, 57(3), 661 - 672, 10.1135/cccc19920661 .
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Holy, Antonin;
Votruba, Ivan;
Cihlar, Tomas;
Olsanska, Lenka, Transport of adefovir (PMEA) in human T-lymphoblastoid cells. Collect. Czech. Chem. Commun. 1997, 62(5), 821 - 828.
Holy, Antonin;
Votruba, Ivan;
Cihlar, Tomas;
Schinkmanova, Marketa;
Shibata, Riri;
Han, Bin;
Liu, Xiaohong, Human N-methyl-AMP/dAMP aminohydrolase (abacavir 5-monophosphate deaminase) is capable of metabolizing N-substituted purine acyclic nucleoside phosphonates. Collect. Czech. Chem. Commun. 2008, 73(2), 275 - 291, 10.1135/cccc20080275 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Cihlar, Tomas;
Naesens, Lieve;
Pomeisl, Karel;
Neyts, Johan;
Tichy, Tomas;
Brehova, Petra;
Laflamme, Genevieve;
Hui, Hon, Synthesis of ester prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] -2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. Journal of Medicinal Chemistry 2010, 53(19), 6825 - 6837, 10.1021/jm901828c .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George, A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities. European Journal of Medicinal Chemistry 2011, 46(9), 3748 - 3754, 10.1016/j.ejmech.2011.05.040 .
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Holy, Antonin;
Jindrich, Jindrich;
Votruba, Ivan;
Otmar, Miroslav;
Cihlar, Tomas;
Rosenberg, Ivan;
Merta, Ales;
Herve, Tchaou Y., Phosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP (dAMP) kinase from L1210 cells. Biochemical Pharmacology 1992, 44(10), 2067 - 2077, 10.1016/0006-2952(92)90110-5 .
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