Sigel, Helmut
Articles
Holy, Antonin;
Chen, Dong;
Bastian, Matthias;
Gregan, Fridrich;
Sigel, Helmut, Ternary Complexes in Solution (Part 55) with Phosphonates as Ligands. Various Intramolecular Equilibria in Mixed-ligand Complexes containing the Antiviral 9-(2-Phosphonomethoxyethyl)adenine, an Adenosine Monophosphate Analogue. J. Chem. Soc., Dalton Trans. (1972-1999) 1993(10), 1537 - 1546.
Holy, Antonin;
Sigel, Helmut;
Song, Bin, METAL ION-COORDINATING PROPERTIES OF THE ANTIVIRAL (S)-9-<3-HYDROXY-2-(PHOSPHONOMETHOXY)PROPYL>ADENINE (HPMPA) IN AQUEOUS SOLUTION. Gazz. Chim. Ital. 1994, 124(10), 387 - 392.
Holy, Antonin;
Dvorakova, Hana;
Sigel, Helmut;
Blindauer, Claudia A.;
Emwas, Abdul H.;
Sletten, Einar, Complex formation of the antiviral 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA) and of its N1, N3, and N7 deaza derivatives with copper(II) in aqueous solution. Chemistry - A European Journal 1997, 3(9), 1526 - 1536.
Holy, Antonin;
Dvorakova, Hana;
Sigel, Helmut;
Blindauer, Claudia A., Solution properties of antiviral adenine-nucleotide analogues. The acid - Base properties of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) and of its N1, N3 and N7 deaza derivatives in aqueous solution. Journal of the Chemical Society. Perkin Transactions 2 1997(11), 2353 - 2363.
Holy, Antonin;
Sigel, Helmut;
Blindauer, Claudia A., Metal ion-binding properties of the nucleotide analogue 1-[2-(phosphonomethoxy)ethyl]cytosine (PMEC) in aqueous solution. Collect. Czech. Chem. Commun. 1999, 64(4), 613 - 632.
Holy, Antonin;
Sigel, Helmut;
Blindauer, Claudia A.;
Sletten, Einar;
Sjastad, Trond I., Aspects of the co-ordination chemistry of the antiviral nucleotide analogue, 9-[2-(phosphonomethoxy)ethyl]-2,6-diaminopurine (PMEDAP). J. Chem. Soc., Dalton Trans. (1972-1999) 1999(21), 3661 - 3671.
Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Kapinos, Larisa E.;
Vilaplana, Rosario A.;
Gonzalez-Vilchez, Francisco, Metal ion-binding properties of 9-(4-phosphonobutyl)adenine (dPMEA), a sister compound of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA), and quantification of the equilibria involving four Cu(PMEA) isomers. Journal of the Chemical Society, Dalton Transactions 2000(13), 2077 - 2084, 10.1039/b001588l 
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Holy, Antonin;
Sigel, Helmut;
Kampf, Gunnar;
Lueth, Marc Sven;
Mueller, Jens;
Lippert, Bernhard, Properties of the ternary (Dien)Pt(PMEA-N7) complex containing diethylenetriamine (Dien) and the antiviral 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). Synthesis, biological screening, acid-base behaviour, and metal ion-binding in aqueous solution. Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences 2000, 55(12), 1141 - 1152.
Holy, Antonin;
Sigel, Helmut;
Kapinos, Larisa E.;
Kampf, Gunnar;
Lueth, Marc Sven;
Mueller, Jens;
Lippert, Bernhard, Formation of ternary complexes by coordination of (diethylenetriamine)-platinum(II) to N1 or N7 of the adenine moiety of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA): Comparison of the acid-base and metal-ion-binding properties of PMEA, (Dien)Pt(PMEA-N1), and (Dien)Pt(PMEA-N7). Chemistry - A European Journal 2001, 7(9), 1899 - 1908, 10.1002/1521-3765(20010504)7:9 .
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Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Vilaplana, Rosario A.;
Gonzalez-Vilchez, Francisco, Solution structures of binary and ternary metal ion complexes of 9-(5-phosphonopentyl)adenine (3′-deoxa-PEEA). A nucleotide analogue related to the antivirally active 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). European Journal of Inorganic Chemistry 2003(16), 2937 - 2947.
Holy, Antonin;
Sigel, Helmut;
Fernandez-Botello, Alfonso;
Escuer, Albert;
Solans, Xavier;
Font-Bardia, Merce;
Moreno, Virtudes, New ternary complexes of copper(II) with 2,2′-bipyridine (bpy) and phosphocholine (PCh) or the quaternary 1-(2-phosphonomethoxy)ethyl derivative of 2,4-diaminopyrimidine (PMEDAPy). European Journal of Inorganic Chemistry 2007(13), 1867 - 1873, 10.1002/ejic.200601002 .
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Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Fernandez-Botello, Alfonso;
Moreno, Virtudes, Metal-ion binding properties of O-phosphonatomethylcholine (PMCh). Effect of the positive charge of a distant trimethylammonium group on the coordinating qualities of a phosph(on)ate group. Inorganica Chimica Acta 2002, 331(1), 109 - 116, 10.1016/S0020-1693(01)00763-0 .
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Holy, Antonin;
Sigel, Helmut;
Fernandez-Botello, Alfonso;
Moreno, Virtudes;
Griesser, Rolf, Acid-base and metal-ion-binding properties of 9-[2-(2-phosphonoethoxy) ethyl]adenine (PEEA), a relative of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). An exercise on the quantification of isomeric complex equilibria in solution. Inorganic Chemistry 2005, 44(14), 5104 - 5117, 10.1021/ic050341j .
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Holy, Antonin;
Sigel, Helmut;
Fernandez-Botello, Alfonso;
Moreno, Virtudes;
Operschall, Bert P., Intramolecular π-π stacking interactions in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and the nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]-2-aminopurine (PME2AP), an isomer of the antivirally active 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). Inorganica Chimica Acta 2009, 362(3), 799 - 810, 10.1016/j.ica.2008.02.035 .
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Holy, Antonin;
Sigel, Helmut;
Fernandez-Botello, Alfonso;
Moreno, Virtudes;
Operschall, Bert P., Metal ion-binding properties of 9-[(2-phosphonomethoxy)ethyl]-2-aminopurine (PME2AP), an isomer of the antiviral nucleotide analogue 9-[(2- phosphonomethoxy)ethyl]adenine (PMEA). Steric guiding of metal ion-coordination by the purine-amino group. Dalton Transactions 2010, 39(27), 6344 - 6354, 10.1039/c005238h .
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Holy, Antonin;
Sigel, Helmut;
Blindauer, Claudia A.;
Gomez-Coca, Raquel B.;
Operschall, Bert P.;
Sigel, Astrid, Extent of intramolecular π-stacks in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and several 2-aminopurine derivatives of the antivirally active nucleotide analog 9-[2-(phosphonomethoxy) ethyl]adenine (PMEA). Chemistry and Biodiversity 2012, 9(9), 2008 - 2034, 10.1002/cbdv.201200022 .
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Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Kapinos, Larisa E.;
Vilaplana, Rosario A.;
Gonzalez-Vilchez, Francisco, Quantification of isomeric equilibria formed by metal ion complexes of 8-[2-(phosphonomethoxy)ethyl]-8-azaadenine (8,8aPMEA) and 9-[2- (phosphonomethoxy)ethyl]-8-azaadenine (9,8aPMEA). Derivatives of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy) ethyl]adenine (PMEA). Journal of Biological Inorganic Chemistry 2004, 9(8), 961 - 972, 10.1007/s00775-004-0591-7 .
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Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Vilaplana, Rosario A.;
Gonzalez-Vilchez, Francisco, Nickel(II), Copper(II) and Zinc(II) complexes of 9-[2-(Phosphonomethoxy) Ethyl]-8-Azaadenine (9,Sapmea), the 8-Aza derivative of the antiviral nucleotide analogue 9-[2-(Phosphonomethoxy)Ethyl] Adenine (Pmea). Quantification of four isomeric species in aqueous solution. Bioinorganic Chemistry and Applications 2004, 2(3-4), 331 - 352.
Holy, Antonin;
Sigel, Helmut;
Blindauer, Claudia A.;
Operschall, Bert P.;
Sigel, Astrid, Extent of intramolecular π stacks in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and 1-[2-(phosphonomethoxy) ethyl]cytosine (PMEC), a relative of antivirally active acyclic nucleotide analogues (Part 72). Zeitschrift fur Anorganische und Allgemeine Chemie 2013, 639(8-9), 1661 - 1673, 10.1002/zaac.201300095 .
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Holy, Antonin;
Sigel, Helmut;
Fernandez-Botello, Alfonso;
Moreno, Virtudes, Intramolecular stacking interactions in ternary copper(II) complexes formed by a heteroaromatic amine and 9-[2-(2-phosphonoethoxy)ethyl]adenine, a relative of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine. Journal of Inorganic Biochemistry 2004, 98(12), 2114 - 2124, 10.1016/j.jinorgbio.2004.08.001 .
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Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Kapinos, Larisa E.;
Vilaplana, Rosario A.;
Gonzalez-Vilchez, Francisco, Intramolecular stacking interactions in ternary copper(II) complexes formed with 2,2′-bipyridine or 1,10-phenanthroline and 9-(4-phosphonobutyl)adenine (dPMEA), the carba relative of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). Journal of Inorganic Biochemistry 2001, 84(1-2), 39 - 46, 10.1016/S0162-0134(00)00194-X .
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Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Kapinos, Larisa E.;
Vilaplana, Rosario A.;
Gonzalez-Vilchez, Francisco, Ternary copper(II) complexes in solution formed with 8-AZA derivatives of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). Metal-Based Drugs 2000, 7(6), 313 - 324.