Janeba, Zlatko
Articles
Holy, Antonin;
Masojidkova, Milena;
Votavova, Hana;
Janeba, Zlatko, Intramolecular cyclization of some acyclic nucleoside analogs. Collect. Czech. Chem. Commun. 1996, 61(3), 442 - 457, 10.1135/cccc19960442 
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Holy, Antonin;
Janeba, Zlatko, Intramolecular Cyclization of Some (S)-9-(3-Hydroxy-2-phosphonomethoxypropyl)adenine Derivatives. Collect. Czech. Chem. Commun. 1996, 61, S116 - S117.
Holy, Antonin;
Masojidkova, Milena;
Janeba, Zlatko, Synthesis of acyclic nucleoside and nucleotide analogs derived from 6-amino-7H-purin-8(9H)-one. Collect. Czech. Chem. Commun. 2000, 65(7), 1126 - 1144.
Holy, Antonin;
Masojidkova, Milena;
Janeba, Zlatko, Synthesis of acyclic nucleoside and nucleotide analogs derived from 6-amino-7H-purine-8(9H)-thione and 8-(methylsulfanyl)adenine. Collect. Czech. Chem. Commun. 2000, 65(11), 1698 - 1712.
Holy, Antonin;
Masojidkova, Milena;
Janeba, Zlatko, Synthesis of 8-amino-and N-substituted 8-aminoadenine derivatives of acyclic nucleoside and nucleotide analogs. Collect. Czech. Chem. Commun. 2001, 66(3), 517 - 532, 10.1135/cccc20010517 .
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Holy, Antonin;
Masojidkova, Milena;
Janeba, Zlatko, Transformation of 8-[(2-hydroxyalkyl)sulfanyl]adenines to 6-amino-7H-purin-8(9H)-one derivatives. Collect. Czech. Chem. Commun. 2001, 66(9), 1393 - 1406, 10.1135/cccc20011393 .
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Holy, Antonin;
Masojidkova, Milena;
Janeba, Zlatko, Alternative synthesis of 9-{3-[(diisopropoxyphosphoryl)-methoxy]-2- hydroxypropyl}adenine and its free phosphonates substituted at the c-8 position of purine base. Collect. Czech. Chem. Commun. 2010, 75(3), 371 - 381, 10.1135/cccc2009569 .
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Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Pohl, Radek;
Clercq, Erik de;
Janeba, Zlatko, Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base. Canadian Journal of Chemistry 2010, 88(7), 628 - 638, 10.1139/V10-054 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Sala, Michal;
Cechova, Lucie, The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination reactions of purines. Tetrahedron 2011, 67(5), 866 - 871, 10.1016/j.tet.2010.12.040 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Balzarini, Jan;
Klepetarova, Blanka;
Clercq, Erik de;
Janeba, Zlatko;
Baszczynski, Ondrej, Synthesis and antiviral activity of N-[3-fluoro-2- (phosphonomethoxy)propyl] analogues derived from N-substituted adenines and 2,6-diaminopurines. Bioorganic and Medicinal Chemistry 2011, 19(7), 2114 - 2124, 10.1016/j.bmc.2011.02.050 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Cesnek, Michal;
Janeba, Zlatko;
Baszczynski, Ondrej, Efficient and 'green' microwave-assisted synthesis of haloalkylphosphonates via the Michaelis-Arbuzov reaction. Green Chemistry 2011, 13(4), 882 - 888, 10.1039/c0gc00509f .
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Holy, Antonin;
Pohl, Radek;
Janeba, Zlatko;
Brehova, Petra;
Sedlacek, Ondrej, The synthesis of the 8-C-substituted 2,6-diamino-9-[2-(phosphonomethoxy) ethyl]purine (PMEDAP) derivatives by diverse cross-coupling reactions. Canadian Journal of Chemistry 2011, 89(4), 488 - 498, 10.1139/V11-001 .
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Holy, Antonin;
Dracinsky, Martin;
Cesnek, Michal;
Janeba, Zlatko;
Brehova, Petra, The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling reaction. Tetrahedron 2011, 67(38), 7379 - 7385, 10.1016/j.tet.2011.07.040 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George, A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities. European Journal of Medicinal Chemistry 2011, 46(9), 3748 - 3754, 10.1016/j.ejmech.2011.05.040 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Balzarini, Jan;
Klepetarova, Blanka;
Janeba, Zlatko;
Baszczynski, Ondrej;
Hradil, Ondrej, An efficient microwave-assisted synthesis and biological properties of polysubstituted pyrimidinyl- and 1,3,5-triazinylphosphonic acids. Tetrahedron 2012, 68(3), 865 - 871, 10.1016/j.tet.2011.11.040 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
Guddat, Luke W.;
Baszczynski, Ondrej, The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. European Journal of Medicinal Chemistry 2013, 67, 81 - 89, 10.1016/j.ejmech.2013.06.032 .
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Janeba, Zlatko;
Francom, Paula;
Shibuya, Susumu;
Robins, Morris J., Nucleic acid related compounds. 116. Nonaqueous diazotization of aminopurine nucleosides. Mechanistic considerations and efficient procedures with tert-butyl nitrite or sodium nitrite. Journal of Organic Chemistry 2002, 67(19), 6788 - 6796, 10.1021/jo0204101 .
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Janeba, Zlatko;
Francom, Paula;
Robins, Morris J., Efficient syntheses of 2-chloro-2′-deoxyadenosine (cladribine) from 2′-deoxyguanosine. Journal of Organic Chemistry 2003, 68(3), 989 - 992, 10.1021/jo020644k .
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Janeba, Zlatko;
Robins, Morris J.;
Liu, Jiangqiong, SAr iodination of 6-chloropurine nucleosides: Aromatic finkelstein reactions at temperatures below -40°C. Organic Letters 2004, 6(17), 2917 - 2919, 10.1021/ol048987n .
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Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Janeba, Zlatko;
Robins, Morris J., Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosides. Journal of Medicinal Chemistry 2005, 48(14), 4690 - 4696, 10.1021/jm050291s .
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Janeba, Zlatko;
Robins, Morris J.;
Lin, Xiaoyu, Functionalization of Guanosine and 2′-Deoxyguanosine at C6: A Modified Appel Process and SAr Displacement of Imidazole. Nucleosides, Nucleotides and Nucleic Acids 2004, 23(1-2), 137 - 147, 10.1081/NCN-120027823 .
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Janeba, Zlatko;
Robins, Morris J.;
Maklad, Noha, An efficient alternative route to 3,6-disubstituted-furo[2,3-d]pyrimidin-2- one analogues. Nucleosides, Nucleotides and Nucleic Acids 2005, 24(10-12), 1729 - 1743, 10.1080/10810730500265757 .
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Janeba, Zlatko;
Robins, Morris J.;
Maklad, Noha, Synthesis of 6-(alkoxymethyl)- and 6-(alkylsulfanylmethyl)furo[2,3-d] pyrimidin-2(3H)-one analogues. Canadian Journal of Chemistry 2006, 84(4), 561 - 568, 10.1139/V06-042 .
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Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Janeba, Zlatko;
Robins, Morris J., Synthesis and biological evaluation of 5-(alkyn-1-yl)-1-(p-toluenesulfonyl) uracil derivatives. Canadian Journal of Chemistry 2006, 84(4), 580 - 586, 10.1139/V06-041 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Mertlikova-Kaiserova, Helena;
Kolman, Viktor;
Kostinova, Alexandra, Efficient synthesis and biological properties of the 2'-trifluoromethyl analogues of acyclic nucleosides and acyclic nucleoside phosphonates. Collect. Czech. Chem. Commun. 2011, 76(10), 1187 - 1198, 10.1135/cccc2011105 .
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Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Klepetarova, Blanka;
Janeba, Zlatko;
Brehova, Petra;
Spacek, Petr, Efficient one-pot synthesis of polysubstituted 6-[(1H-1,2,3-Triazol-1-Yl) Methyl]uracils through the "click" protocol. Collect. Czech. Chem. Commun. 2011, 76(9), 1121 - 1131, 10.1135/cccc2011074 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Kaiser, Martin Maxmilian, A novel type of acyclic nucleoside phosphonates derived from 2-(phosphonomethoxy)propanoic acid. Tetrahedron 2012, 68(21), 4003 - 4012, 10.1016/j.tet.2012.03.066 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Baszczynski, Ondrej;
Prochazkova, Eliska, Microwave-assisted hydrolysis of phosphonate diesters: An efficient protocol for the preparation of phosphonic acids. Green Chemistry 2012, 14(8), 2282 - 2288, 10.1039/c2gc35547g .
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Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Wang, Tzu-Hsuan, Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry 2012, 55(13), 6209 - 6223, 10.1021/jm300662d .
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Jansa, Petr;
Janeba, Zlatko;
Drainsky, Martin;
Kaiser, Martin Maxmilian;
Baszczynski, Ondej;
Spaek, Petr, An efficient oxa-Michael addition to diethyl vinylphosphonate under mild reaction conditions. RSC Advances 2012, 2(4), 1282 - 1284, 10.1039/c2ra00938b .
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Krecmerova, Marcela;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Neyts, Johan;
Kasicka, Vaclav;
Stepan, George;
Sazelova, Petra;
Auwerx, Joeri;
Kiss, Eleonora;
Goris, Nesya, 9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro. Bioorganic and Medicinal Chemistry 2013, 21(5), 1199 - 1208, 10.1016/j.bmc.2012.12.044 .
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Dracinsky, Martin;
Cesnek, Michal;
Krystof, Vladimir;
Janeba, Zlatko;
Doleckova, Iva;
Brynda, Jiri;
Voller, Jiri, Synthesis and biological evaluation of guanidino analogues of roscovitine. European Journal of Medicinal Chemistry 2013, 62, 443 - 452, 10.1016/j.ejmech.2013.01.021 .
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Hockova, Dana;
Slavetinska, Lenka;
Janeba, Zlatko;
Naesens, Lieve;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Tichy, Tomas;
Spacek, Petr;
Wang, Tzu-Hsuan;
Edstein, Michael D.;
Chavchich, Marina, Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. Journal of Medicinal Chemistry 2013, 56(6), 2513 - 2526, 10.1021/jm301893b .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Cechova, Lucie, A conversion of aromatic thiocyanates into sulfothioates: New synthetic route to aromatic Bunte salts. RSC Advances 2013, 3(8), 2650 - 2654, 10.1039/c2ra21975a .
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Cesnek, Michal;
Janeba, Zlatko;
Trejtnar, Frantisek;
Pavek, Petr;
Mandikova, Jana;
Volkova, Marie;
Kubicek, Vladimir, Interactions with selected drug renal transporters and transporter-mediated cytotoxicity in antiviral agents from the group of acyclic nucleoside phosphonates. Toxicology 2013, 311(3), 135 - 146, 10.1016/j.tox.2013.07.004 .
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Janeba, Zlatko, Purine 8-O- and 8-S-cyclonucleosides - Synthesis and Properties. Chemicke Listy 2000, 94(6), 355 - 370.
Janeba, Zlatko;
Baszczynski, Ondrej, Medicinal chemistry of fluorinated cyclic and acyclic nucleoside phosphonates. Medicinal Research Reviews 2013, 33(6), 1304 - 1344, 10.1002/med.21296 .
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Dracinsky, Martin;
Janeba, Zlatko;
Cechova, Lucie;
Prochazkova, Eliska, A switchable intramolecular hydrogen bond in polysubstituted 5-nitrosopyrimidines. Journal of Organic Chemistry 2013, 78(20), 10121 - 10133, 10.1021/jo401441z .
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Janeba, Zlatko;
Solinova, Veronika;
Kasicka, Vaclav;
Kaiser, Martin Maxmilian;
Lukac, Milos, Enantiopurity analysis of new types of acyclic nucleoside phosphonates by capillary electrophoresis with cyclodextrins as chiral selectors. Journal of Separation Science 2014, 37(3), 295 - 303, 10.1002/jssc.201301092 .
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Cesnek, Michal;
Smidkova, Marketa;
Tloust'Ova, Eva;
Janeba, Zlatko;
Mertlikova-Kaiserova, Helena;
Dvorakova, Alexandra, Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis. Antimicrobial Agents and Chemotherapy 2014, 58(2), 664 - 671, 10.1128/AAC.01685-13 .
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Janeba, Zlatko;
Fojtova, Miloslava;
Ogrocka, Anna;
Polanska, Pavla;
Majerova, Eva;
Fajkus, Jiri, Compromised telomere maintenance in hypomethylated Arabidopsis thaliana plants. Nucleic Acids Research 2014, 42(5), 2919 - 2931, 10.1093/nar/gkt1285 .
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Hockova, Dana;
Janeba, Zlatko, The role of acyclic nucleoside phosphonates as potential antimalarials. Chemicke Listy 2014, 108(4), 335 - 343.