Neyts, Johan
Articles
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Naesens, Lieve;
Piskala, Alois;
Neyts, Johan, Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2- (phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds. Journal of Medicinal Chemistry 2007, 50(5), 1069 - 1077, 10.1021/jm061281+ 
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Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Naesens, Lieve;
Neyts, Johan, Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5- azacytosine: Synthesis and antiviral activity. Journal of Medicinal Chemistry 2007, 50(23), 5765 - 5772, 10.1021/jm0707166 .
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Krecmerova, Marcela;
Holy, Antonin;
Votruba, Ivan;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Naesens, Lieve;
Neyts, Johan, Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine. Biochemical Pharmacology 2008, 76(8), 997 - 1005, 10.1016/j.bcp.2008.08.009 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Neyts, Johan;
De Palma, Armando M., Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol. Collect. Czech. Chem. Commun. 2009, 74(3), 487 - 502, 10.1135/cccc2008204 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Neyts, Johan;
De Palma, Armando M., Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.0]nonane- 9-methanol and 4-oxatricyclo[4.3.1.0]decane-10-methanol, compounds with activity against coxsackie viruses. Collect. Czech. Chem. Commun. 2009, 74(3), 469 - 485, 10.1135/cccc2008193 .
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Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Hrebabecky, Hubert;
Sala, Michal;
Neyts, Johan;
De Palma, Armando M., Norbornane as the novel pseudoglycone moiety in nucleosides. Tetrahedron 2009, 65(45), 9291 - 9299, 10.1016/j.tet.2009.09.018 .
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Holy, Antonin;
Masojidkova, Milena;
Sala, Michal;
Neyts, Johan;
De Palma, Armando M.;
Hebabecky, Hubert;
Draeinsky, Martin, Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene. Collect. Czech. Chem. Commun. 2010, 75(1), 1 - 20, 10.1135/cccc2009116 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Sala, Michal;
Nencka, Radim;
Neyts, Johan;
De Palma, Armando M.;
Leyssen, Pieter, Design, synthesis, and biological evaluation of novel coxsackievirus B3 inhibitors. Bioorganic and Medicinal Chemistry 2010, 18(12), 4374 - 4384, 10.1016/j.bmc.2010.04.081 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Cihlar, Tomas;
Naesens, Lieve;
Pomeisl, Karel;
Neyts, Johan;
Tichy, Tomas;
Brehova, Petra;
Laflamme, Genevieve;
Hui, Hon, Synthesis of ester prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] -2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. Journal of Medicinal Chemistry 2010, 53(19), 6825 - 6837, 10.1021/jm901828c .
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Holy, Antonin;
De Clercq, Erik;
Naesens, Lieve;
Neyts, Johan;
Stittelaar, Koert J.;
Van Amerongen, Geert;
Van Lavieren, Rob F.;
Niesters, Hubert G. M.;
Fries, Edwin;
Maas, Chantal;
Mulder, Paul G. H.;
Van Der Zeijst, Ben A. M.;
Osterhaus, Albert D. M. E., Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection. Nature 2006, 439(7077), 745 - 748, 10.1038/nature04295 .
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Krecmerova, Marcela;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Neyts, Johan;
Kasicka, Vaclav;
Stepan, George;
Sazelova, Petra;
Auwerx, Joeri;
Kiss, Eleonora;
Goris, Nesya, 9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro. Bioorganic and Medicinal Chemistry 2013, 21(5), 1199 - 1208, 10.1016/j.bmc.2012.12.044 .
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Patents
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Naesens, Lieve;
Piskala, Alois;
Neyts, Johan, AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS, WO2007/65231, 2007.
Holy, Antonin;
Hrebabecky, Hubert;
Sala, Michal;
Neyts, Johan;
DE PALMA, Armando, NEW ANTIVIRAL COMPOUNDS, WO2008/131502, 2008.
Holy, Antonin;
Hrebabecky, Hubert;
Sala, Michal;
Neyts, Johan;
DE PALMA, Armando, NEW ANTI-VIRAL NUCLEOSIDE ANALOGS, WO2008/131501, 2008.