De Jersey, John
Articles
Holy, Antonin;
Hockova, Dana;
Keough, Dianne T.;
Naesens, Lieve M. J.;
Skinner-Adams, Tina S.;
De Jersey, John;
Guddat, Luke W., Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: A new class of antimalarial therapeutics. Journal of Medicinal Chemistry 2009, 52(14), 4391 - 4399, 10.1021/jm900267n .
Krecmerova, Marcela;
Holy, Antonin;
Cesnek, Michal;
Hockova, Dana;
Naesens, Lieve;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Brereton, Ian M.;
Winzor, Donald J., Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: A target for anti-malarial chemotherapy. Molecular and Biochemical Parasitology 2010, 173(2), 165 - 169, 10.1016/j.molbiopara.2010.05.018 .
Holy, Antonin;
Hockova, Dana;
Naesens, Lieve;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W., 6-oxopurine phosphoribosyltransferase: A target for the development of antimalarial drugs. Current Topics in Medicinal Chemistry 2011, 11(16), 2085 - 2102, 10.2174/156802611796575911 .
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Wang, Tzu-Hsuan, Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry 2012, 55(13), 6209 - 6223, 10.1021/jm300662d .
Hockova, Dana;
Slavetinska, Lenka;
Janeba, Zlatko;
Naesens, Lieve;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Tichy, Tomas;
Spacek, Petr;
Wang, Tzu-Hsuan;
Edstein, Michael D.;
Chavchich, Marina, Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. Journal of Medicinal Chemistry 2013, 56(6), 2513 - 2526, 10.1021/jm301893b .
Krecmerova, Marcela;
Hockova, Dana;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Rejman, Dominik;
Spacek, Petr;
Eng, Wai Soon;
Jans, Harmen;
West, Nicholas P.;
Naesens, Lieve M.J., Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: Potential for new antibacterial agents. Journal of Medicinal Chemistry 2013, 56(17), 6967 - 6984, 10.1021/jm400779n .