Mertlikova-Kaiserova, Helena

Holy, Antonin;
Votruba, Ivan;
Tloustova, Eva;
Mertlikova-Kaiserova, Helena;
Rumlova, Michaela;
Prochazkova, Eliska, Point mutations in human guanylate kinase account for acquired resistance to anticancer nucleotide analogue PMEG. Biochemical Pharmacology 2011, 82(2), 131 - 138, 10.1016/j.bcp.2011.04.002
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Mertlikova-Kaiserova, Helena;
Prochazkova, Eliska, Determination of the antioxidative activity of substituted 5-aminopyrimidines. Free Radical Research 2012, 46(1), 61 - 67, 10.3109/10715762.2011.638292
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Cechova, Lucie;
Mertlikova-Kaiserova, Helena;
Prochazkova, Eliska;
Brezinova, Anna, Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening. Bioorganic and Medicinal Chemistry Letters 2012, 22(20), 6405 - 6409, 10.1016/j.bmcl.2012.08.065
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Holy, Antonin;
Votruba, Ivan;
Hajek, Miroslav;
Mertlikova-Kaiserova, Helena;
Cvilink, Viktor, Distinct modulation of telomere length in two T-lymphoblastic leukemia cell lines by cytotoxic nucleoside phosphonates PMEG and PMEDAP. Eur. J. Pharmacol. 2010, 643(1), 6 - 12, 10.1016/j.ejphar.2010.06.006
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Holy, Antonin;
Votruba, Ivan;
Hajek, Miroslav;
Mertlikova-Kaiserova, Helena;
Matousova, Marika, Role of caspases and CD95/Fas in the apoptotic effects of a nucleotide analog PMEG in CCRF-CEM cells. Anticancer Research 2010, 30(7), 2791 - 2798.
Holy, Antonin;
Votruba, Ivan;
Mertlikova-Kaiserova, Helena;
Nejedla, Michaela, Involvement of MAP kinases in the cytotoxicity of acyclic nucleoside phosphonates. Anticancer Research 2012, 32(2), 497 - 501.
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Mertlikova-Kaiserova, Helena;
Kolman, Viktor;
Kostinova, Alexandra, Efficient synthesis and biological properties of the 2'-trifluoromethyl analogues of acyclic nucleosides and acyclic nucleoside phosphonates. Collect. Czech. Chem. Commun. 2011, 76(10), 1187 - 1198, 10.1135/cccc2011105
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Cesnek, Michal;
Smidkova, Marketa;
Tloust'Ova, Eva;
Janeba, Zlatko;
Mertlikova-Kaiserova, Helena;
Dvorakova, Alexandra, Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis. Antimicrobial Agents and Chemotherapy 2014, 58(2), 664 - 671, 10.1128/AAC.01685-13
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