Ledvina, Miroslav

Holy, Antonin; Korvasova, Zina; Drasar, Lukas; Masek, Josef; Knotigova, Pavlina Turanek; Kulich, Pavel; Matiasovic, Jan; Kovarcik, Kamil; Bartheldyova, Eliska; Koudelka, Stepan; Skrabalova, Michaela; Miller, Andrew D.; Ledvina, Miroslav; Turanek, Jaroslav, Antiviral effect of HPMPC (Cidofovir®), entrapped in cationic liposomes: In vitro study on MDBK cell and BHV-1 virus. Journal of Controlled Release 2012, 160(2), 330 - 338, 10.1016/j.jconrel.2012.01.040 .

Trnka, Tomas; Jindrich, Jindrich; Saman, David; Ledvina, Miroslav; Vesely, Jan, Improved synthesis of 1,2-trans-acetates and 1,2-trans ethyl 1-thioglycosides derived from 3,4,6-tri-o-acetyl-2-deoxy-2-phthalimido-D-hexopyranosides. Collect. Czech. Chem. Commun. 2003, 68(7), 1264 - 1274, 10.1135/cccc20031264 .

Trnka, Tomas; Jindrich, Jindrich; Saman, David; Ledvina, Miroslav; Vesely, Jan, Synthesis of 2-amino-2-deoxy-β-D-galactopyranosyl-(1→4)-2-amino- 2-deoxy-β-D-galactopyranosides: Using various 2-deoxy-2-phthalimido-D- galactopyranosyl donors and acceptors. Collect. Czech. Chem. Commun. 2004, 69(10), 1914 - 1938, 10.1135/cccc20041914 .

Zajicek, Jaroslav; Ledvina, Miroslav; Farkas, Jiri; Jezek, Jan; Zaoral, Milan, AN ALTERNATIVE SYNTHESIS OF O-(2-ACETAMIDO-2-DEOXY-β-D-GLUCOPYRANOSYL)-(1-4)-N-ACETYLNORMURAMOYL-L-α-AMINOBUTANOYL-D-ISOGLUTAMINE. Collect. Czech. Chem. Commun. 1989, 54(10), 2784 - 2794.

Ledvina, Miroslav; Farkas, Jiri, ALTERNATIVE SYNTHESIS OF 4-METHYL-2H-1,2,6-THIADIAZIN-3(6H)-ONE 1,1-DIOXIDE, A STRUCTURAL ANALOGUE OF THYMINE. Collect. Czech. Chem. Commun. 1984, 49(4), 840 - 851.

Ledvina, Miroslav; Farkas, Jiri, SYNTHESIS OF METHYL 3-(N'-ALKYLUREIDO)-2-METHYL-2-PROPENOATES AND THEIR CYCLIZATION TO 3-ALKYL-5-METHYLURACILS. Collect. Czech. Chem. Commun. 1982, 47(2), 676 - 688.

Saman, David; Ledvina, Miroslav; Jezek, Jan, SYNTHESIS OF O-(2-DEOXY-2-STEAROYLAMINO-β-D-GLUCOPYRANOSYL)-(1<*>4)-N-ACETYLNORMURAMOYL-L-α-AMINOBUTANOYL-D-ISOGLUTAMINE, A LIPOPHILIC DISACCHARIDE ANALOGUE OF MDP. Collect. Czech. Chem. Commun. 1992, 57(3), 579 - 589, 10.1135/cccc19920579 .

Zajicek, Jaroslav; Ledvina, Miroslav; Jezek, Jan; Zaoral, Milan; Farkas, Jirz; Brokes, Josef, THE SYNTHESIS OF O-(2-ACETAMIDO-2-DEOXY-β-D-GLUCOPYRANOSYL)-(1->4)-N-ACETYLNORMURAMOYL-L-α-AMINOBUTANOYL-D-ISOGLUTAMINE. Carbohydr. Res. 1987, 163, 63 - 72, 10.1016/0008-6215(87)80165-9 .

Ledvina, Miroslav; Farkas, Jiri, CYCLIZATION DICHOTOMY OF ESTERS OF 3-UREIDO-2-CYANO-2-PROPENOIC AND 3-UREIDO-2-ACYL-2-PROPENOIC ACIDS. Collect. Czech. Chem. Commun. 1994, 59(8), 1841 - 1852, 10.1135/cccc19941841 .

Saman, David; Ledvina, Miroslav; Jezek, Jan; Vaisar, Tomas; Hribalova, Vera, Synthesis of O-<2-acetamido-2-deoxy-6-O-stearoyl- and -6-O-(2-tetradecylhexadecanoyl)-β-D-glucopyranosyl>-(1<*>4)-N-acetylnormuramoyl-L-α-aminobutanoyl-D-isoglutamine, lipophilic disaccharide analogues of MDP. Carbohydr. Res. 1994, 251, 269 - 284, 10.1016/0008-6215(94)84291-4 .

Ledvina, Miroslav; Jezek, Jan; Vaisar, Tomas, Fragmentation of Lipophilic Disaccharide Analogs of Muramyl Dipeptide (MDP) in FAB Mass Spectrometry, a Characterization of Lipophilic Substitution. J. Mass Spectrom. 1995, 30(5), 767 - 768, 10.1002/jms.1190300518 .

Trnka, Tomas; Saman, David; Ledvina, Miroslav; Jezek, Jan; Zyka, Daniel, New effective synthesis of (N-acetyl- and N-stearoyl-2-amino-2-deoxy-β-D-glucopyranosyl)-(1→4)N-acetyln or-muramoyl-L-2-aminobutanoyl-D-isoglutamine, analogs of GMDP with immunopotentiating activity. Collect. Czech. Chem. Commun. 1998, 63(4), 577 - 589.

Saman, David; Ledvina, Miroslav; Jezek, Jan; Hribalova, Vera, Synthesis and immunomodulating activity of lipophilic analogs of N-acetylnormuramoyl-L-2-aminobutanoyl-D-isoglutamine. Collect. Czech. Chem. Commun. 1998, 63(4), 590 - 598.

Saman, David; Ledvina, Miroslav; Kovarikova, Radka, Cyclization dichotomy of D-xylo-hex-5-ulosonamides and synthesis of piperidine analogs of aldohexoses and aldohexono-1,5-lactones. Collect. Czech. Chem. Commun. 1999, 64(4), 673 - 684.

Saman, David; Ledvina, Miroslav; Jezek, Jan; Pavelova, Radka; Rohlenova, Anna, Synthesis of normuramic acid Carba analog and its glycopeptide derivative resistant to β-elimination splitting of the side chain. Collect. Czech. Chem. Commun. 2000, 65(11), 1726 - 1736.

Saman, David; Ledvina, Miroslav; Rohlenova, Anna; Bezouska, Karel, Synthesis of linear and branched regioisomeric chitooligosaccharides as potential mimetics of natural oligosaccharide ligands of natural killer cells NKR-P1 and CD69 lectin receptors. Collect. Czech. Chem. Commun. 2004, 69(9), 1781 - 1804, 10.1135/cccc20041781 .

Tislerova, Iva; Trnka, Tomas; Dzoganova, Martina; Saman, David; Ledvina, Miroslav; Vesely, Jan; Rohlenova, Anna, Preparation of ethyl 2-azido-2-deoxy-1-thio-β-D-mannopyranosides, and their rearrangement to 2-S-ethyl-2-thio-β-D-mannopyranosylamines. Synthesis 2006(4), 699 - 705, 10.1055/s-2006-926297 .

Tislerova, Iva; Trnka, Tomas; Tursky, Matyas; Ledvina, Miroslav; Vesely, Jan, Synthesis of a new type of D-mannosamine glycosyl donor and acceptor and their use for the preparation of oligosaccharides consisting of D-mannosamine units linked by α(1→4)-glycosidic bonds. Synthesis 2008(16), 2610 - 2616, 10.1055/s-2008-1067197 .

Saman, David; Sklenar, Vladimir; Ledvina, Miroslav; Zyka, Daniel; Bezouska, Karel; Kovalova, Anna; Kubickova, Monika; Zidek, Lukas; Pompach, Petr; Kavan, Daniel; Bily, Jan; Vanek, Ondrej; Kubinkova, Zuzana; Libigerova, Martina; Ivanova, Ljubina; Antolikova, Maria; Mrazek, Hynek; Rozbesky, Daniel; Hofbauerova, Katerina; Kren, Vladimir, Synthetic N -Acetyl- d -glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69 killer lymphocytes upon dimerization via a hydrophilic flexible linker. Journal of Medicinal Chemistry 2010, 53(10), 4050 - 4065, 10.1021/jm100055b .

Ledvina, Miroslav; Petrak, Vaclav; Grieten, Lars; Taylor, Andrew; Fendrych, Frantisek; Janssens, Stoffel D.; Nesladek, Milos; Haenen, Ken; Wagner, Patrick, Monitoring of peptide induced disruption of artificial lipid membrane constructed on boron-doped nanocrystalline diamond by electrochemical impedance spectroscopy. Physica Status Solidi (A) Applications and Materials Science 2011, 208(9), 2099 - 2103, 10.1002/pssa.201100036 .

Ledvina, Miroslav; Cigler, Petr; Taylor, Andrew; Fendrych, Frantisek; Nesladek, Milos; Petrakova, Vladimira; Vacik, Jiri; Stursa, Jan; Kucka, Jan, Luminescence properties of engineered nitrogen vacancy centers in a close surface proximity. Physica Status Solidi (A) Applications and Materials Science 2011, 208(9), 2051 - 2056, 10.1002/pssa.201100035 .

Miller, Andrew D.; Ledvina, Miroslav; Turanek, Jaroslav; Hribalova, Vera; Kasna, Andrea; Vacek, Antonin; Krejci, Josef, Liposomal preparations of muramyl glycopeptides as immunomodulators and adjuvants. Vaccine 2006, 24(SUPPL. 2), S2/90-S2/91, 10.1016/j.vaccine.2005.01.137 .

Ledvina, Miroslav; Wang, Xiu-Fang; Birringer, Marc; Dong, Lan-Feng; Veprek, Pavel; Low, Pauline; Swettenham, Emma; Stantic, Marina; Yuan, Lin-Hong; Zobalova, Renata; Wu, Kun; Ralph, Stephen J; Neuzil, Jiri, A peptide conjugate of vitamin E succinate targets breast cancer cells with high ErbB2 expression.. Cancer research 2007, 67(7), 3337 - 3344, 10.1158/0008-5472.CAN-06-2480 .

Orsag, Petr; Miller, Andrew D.; Ledvina, Miroslav; Turanek, Jaroslav; Kvardova, Veronika; Raska, Milan, Quantitative real-time PCR study on persistence of pDNA vaccine pVax-Hsp60 TM814 in beef muscles. Genetic Vaccines and Therapy 2008, 6, 10.1186/1479-0556-6-11 .

Korvasova, Zina; Masek, Josef; Kulich, Pavel; Bartheldyova, Eliska; Koudelka, Stepan; Skrabalova, Michaela; Miller, Andrew D.; Ledvina, Miroslav; Turanek, Jaroslav; Raska, Milan; Kratochvilova, Irena, Immobilization of histidine-tagged proteins on monodisperse metallochelation liposomes: Preparation and study of their structure. Analytical Biochemistry 2011, 408(1), 95 - 104, 10.1016/j.ab.2010.08.023 .

Sebela, Marek; Vrbkova, Jana; Korvasova, Zina; Masek, Josef; Kulich, Pavel; Bartheldyova, Eliska; Koudelka, Stepan; Skrabalova, Michaela; Miller, Andrew D.; Ledvina, Miroslav; Turanek, Jaroslav; Zyka, Daniel; Raska, Milan; Kratochvilova, Irena; Turanek-Knotigova, Pavlina; Plockova, Jana; Skodova, Petra; Krupka, Michal; Zachova, Katerina; Czernekova, Lydie; Horynova, Milada; Michalek, Jaroslav, Metallochelating liposomes with associated lipophilised norAbuMDP as biocompatible platform for construction of vaccines with recombinant His-tagged antigens: Preparation, structural study and immune response towards rHsp90. Journal of Controlled Release 2011, 151(2), 193 - 201, 10.1016/j.jconrel.2011.01.016 .

Cerny, Jiri; Ledvina, Miroslav; Stursa, Jan; Dong, Lan-Feng; Ralph, Stephen J; Neuzil, Jiri; Jameson, Victoria J A; Tilly, David; Mahdavian, Elahe; Marin-Hernandez, Alvaro; Hernandez-Esquivel, Luz; Rodriguez-Enriquez, Sara; Witting, Paul K; Stantic, Bela; Rohlena, Jakub; Truksa, Jaroslav; Kluckova, Katarina; Dyason, Jeffrey C; Salvatore, Brian A; Moreno-Sanchez, Rafael; Coster, Mark J; Smith, Robin A J, Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II.. Journal of Biological Chemistry 2011, 286(5), 3717 - 3728, 10.1074/jbc.M110.186643 .

Ledvina, Miroslav; Turanek, Jaroslav; Stursa, Jan; Dong, Lan-Feng; Stantic, Marina; Zobalova, Renata; Neuzil, Jiri; Tilly, David; Mahdavian, Elahe; Rohlena, Jakub; Truksa, Jaroslav; Kluckova, Katarina; Jameson, Victoria J.A.; Prochazka, Lubomir; Valis, Karel; Freeman, Ruth; Witting, Paul K.; Norberg, Erik; Goodwin, Jacob; Salvatore, Brian A.; Novotna, Jana; Hozak, Pavel; Zhivotovsky, Boris; Coster, Mark J.; Ralph, Stephen J.; Smith, Robin A.J., Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy. Free Radical Biology and Medicine 2011, 50(11), 1546 - 1555, 10.1016/j.freeradbiomed.2011.02.032 .

Ledvina, Miroslav; Stursa, Jan; Dong, Lan-Feng; Zobalova, Renata; Neuzil, Jiri; Tilly, David; Rohlena, Jakub; Kluckova, Katarina; Goodwin, Jacob; Hozak, Pavel; Coster, Mark J.; Pecinova, Alena; Philimonenko, Anatoly; Banerjee, Jaideep; Sen, Chandan K.; Houstek, Josef, Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: Potential benefit against tumor angiogenesis but caution against wound healing. Antioxidants and Redox Signaling 2011, 15(12), 2923 - 2935, 10.1089/ars.2011.4192 .

Sebela, Marek; Korvasova, Zina; Masek, Josef; Kulich, Pavel; Bartheldyova, Eliska; Koudelka, Stepan; Skrabalova, Michaela; Miller, Andrew D.; Ledvina, Miroslav; Turanek, Jaroslav; Raska, Milan; Plockova, Jana; Krupka, Michal; Zachova, Katerina; Czernekova, Lydie; Horynova, Milada; Knoetigova, Pavlina Turanek; Strouhal, Ondrej, Enhancement of immune response towards non-lipidized Borrelia burgdorferi recombinant OspC antigen by binding onto the surface of metallochelating nanoliposomes with entrapped lipophilic derivatives of norAbuMDP. Journal of Controlled Release 2012, 160(2), 374 - 381, 10.1016/j.jconrel.2012.02.017 .

Ledvina, Miroslav; Drasara, Lukas, Gene Therapy: Cationic Lipids for Construction of Nonviral Vectors of Nucleic Acids. Chemicke Listy 2012, 106(7), 646 - 652.

Ledvina, Miroslav; Cigler, Petr; Taylor, Andrew; Fendrych, Frantisek; Nesladek, Milos; Petrakova, Vladimira; Vacik, Jiri; Stursa, Jan; Kucka, Jan; Kratochvilova, Irena; Fiserova, Anna; Kneppo, Peter, Luminescence of nanodiamond driven by atomic functionalization: Towards novel detection principles. Advanced Functional Materials 2012, 22(4), 812 - 819, 10.1002/adfm.201101936 .

Ledvina, Miroslav; Cigler, Petr; Hofman, Jakub; Buncek, Martin; Haluza, Radovan; Streinz, Ludvik, In vitro transfection mediated by dendrigraft poly(L-lysines): The effect of structure and molecule size. Macromolecular Bioscience 2013, 13(2), 167 - 176, 10.1002/mabi.201200303 .

Ledvina, Miroslav; Cigler, Petr; Petrak, Vaclav; Nesladek, Milos; Petrakova, Vladimira; Stursa, Jan; Kucka, Jan; Havlik, Jan; Rehor, Ivan; Gulka, Michal; Ralis, Jan; Rendler, Torsten; Lee, San-Yung; Reuter, Rolf; Wrachtrup, Joerg, Boosting nanodiamond fluorescence: Towards development of brighter probes. Nanoscale 2013, 5(8), 3208 - 3211, 10.1039/c2nr32778c .

Trnka, Tomas; Ledvina, Miroslav; Pecka, Jaroslav; Jezek, Jan; Veprek, Pavel; Velek, Jiri; Velkova, Vlasta; Vondrasek, Jiri; Pisacka, Martin, Solid phase synthesis of glycopeptide dendrimers with Tn antigenic structure and their biological activities. Part I. Journal of Peptide Science 1999, 5(1), 46 - 55, 10.1002/(SICI)1099-1387(199901)5:1 .

Ledvina, Miroslav; Cigler, Petr; Kucka, Jan; Rehor, Ivan; Mackova, Hana; Filippov, Sergey K.; Proks, Vladimir; Slegerova, Jitka; Turner, Stuart; Van Tendeloo, Gustaaf; Hruby, Martin, Fluorescent nanodiamonds with bioorthogonally reactive protein-resistant polymeric coatings. ChemPlusChem 2014, 79(1), 21 - 24, 10.1002/cplu.201300339 .

Ledvina, Miroslav; Cigler, Petr; Petrakova, Vladimira; Kucka, Jan; Rehor, Ivan; Proks, Vladimir; Slegerova, Jitka; Turner, Stuart; Adam, Marie-Pierre; Treussart, Francois; Bals, Sara; Sacha, Pavel; Wen, Amy M.; Steinmetz, Nicole F., Fluorescent nanodiamonds embedded in biocompatible translucent shells. Small 2014, 10(6), 1106 - 1115, 10.1002/smll.201302336 .

Ledvina, Miroslav; Turanek, Jaroslav; HIPLER, Karsten; MILLER, Andrew, COMPOUND, WO2009/115782, 2009.

Ledvina, Miroslav; Turanek, Jaroslav; HIPLER, Karsten; MILLER, Andrew, COMPOUND, US2011/2983, 2011.

Korvasova, Zina; Drasar, Lukas; Ledvina, Miroslav; Turanek, Jaroslav, LIPOPOLYAMINES OF SPERMINE TYPE FOR CONSTRUCTION OF LIPOSOMAL TRANSFECTION SYSTEMS, WO2013/104346, 2013.