Molecular Formula: C9H14N5O4P
Molecular weight: 287.212321
InChi: InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m0/s1
InChi Key: SGOIRFVFHAKUTI-LURJTMIESA-N
SMILES: c12c(c(ncn2)N)ncn1C[C@@H](OCP(=O)(O)O)C
Chemical Name
(R)PMPA
(S)-9-(2-(phosphonomethoxy)propyl)adenine
(S)-9-(2-phosphonomethoxypropyl)adenine
(S)-9-(2-phosphonylmethoxypropyl)adenine
(S)-9-[2-(phosphonomethoxy)propyl]adenine
9-((R)-2-phosphonomethoxypropyl)adenine
9-[(S)-2-(phosphonomethoxy)propyl]adenine
(R)PMPA
(S)-9-(2-(phosphonomethoxy)propyl)adenine
(S)-9-(2-phosphonomethoxypropyl)adenine
(S)-9-(2-phosphonylmethoxypropyl)adenine
(S)-9-[2-(phosphonomethoxy)propyl]adenine
9-((R)-2-phosphonomethoxypropyl)adenine
9-[(S)-2-(phosphonomethoxy)propyl]adenine
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dvorakova, Hana
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
De Clercq, Erik
Hockova, Dana
Fanfrlik, Jindrich
Tloustova, Eva
Horska, Kvetoslava
Zidek, Zdenek
Krejcova, Romana
Kmonickova, Eva
Potmesil, Petr
Kmoniekova, Eva
Duraffour, Sophie
Van Den Oord, Joost
De Vos, Rita
Crance, Jean-Marc
Garin, Daniel
Brehova, Petra
Tryznova, Jana
Prenosil, Ondrej
Holy, Antonin
Dvorakova, Hana
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
De Clercq, Erik
Hockova, Dana
Fanfrlik, Jindrich
Tloustova, Eva
Horska, Kvetoslava
Zidek, Zdenek
Krejcova, Romana
Kmonickova, Eva
Potmesil, Petr
Kmoniekova, Eva
Duraffour, Sophie
Van Den Oord, Joost
De Vos, Rita
Crance, Jean-Marc
Garin, Daniel
Brehova, Petra
Tryznova, Jana
Prenosil, Ondrej
Articles
Holy, Antonin;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. I. THE STEPWISE APPROACH. Collect. Czech. Chem. Commun. 1995, 60(7), 1196 - 1212, 10.1135/cccc19951196 
.
.
Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL)DERIVATIVES OF PURINE AND PYRIMIDINE BASES. II. THE SYNTHON APPROACH. Collect. Czech. Chem. Commun. 1995, 60(8), 1390 - 1409, 10.1135/cccc19951390 .
.
Holy, Antonin;
Masojidkova, Milena;
Hockova, Dana, "Abbreviated" NADanalogues containing a phosphonate function. Collect. Czech. Chem. Commun. 1996, 61(10), 1538 - 1548, 10.1135/cccc19961538 .
.
Holy, Antonin;
Hockova, Dana, "Abbreviated" NAD Analogues Containing a Phosphonate Function. Collect. Czech. Chem. Commun. 1996, 61, S52 - S54.
Holy, Antonin;
Votruba, Ivan;
Zidek, Zdenek, Inhibition of Murine Lymphocyte Proliferation by N-Substituted Acyclic Purine Nucleoside Phosphonates. Collect. Czech. Chem. Commun. 1996, 61, S182 - S187.
Holy, Antonin;
Votruba, Ivan;
Horska, Kvetoslava;
Krejcova, Romana, Phosphorylation of purine (phosphonomethoxy)alkyl derivatives by mitochondrial AMP kinase (AK2 type) from L1210 cells. Collect. Czech. Chem. Commun. 2000, 65(10), 1653 - 1668.
Holy, Antonin;
Zidek, Zdenek;
Potmesil, Petr;
Kmoniekova, Eva, Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N-substituted adenines, and 2,6-diaminopurines. Eur. J. Pharmacol. 2003, 475(1-3), 149 - 159, 10.1016/S0014-2999(03)02110-1 .
.
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Duraffour, Sophie;
Van Den Oord, Joost;
De Vos, Rita;
Crance, Jean-Marc;
Garin, Daniel, Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models. Antimicrobial Agents and Chemotherapy 2007, 51(12), 4410 - 4419, 10.1128/AAC.00838-07 .
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Holy, Antonin;
Zidek, Zdenek;
Kmonickova, Eva, Secretion of antiretroviral chemokines by human cells cultured with acyclic nucleoside phosphonates. Eur. J. Pharmacol. 2007, 574(1), 77 - 84, 10.1016/j.ejphar.2007.07.024 .
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Holy, Antonin;
Votruba, Ivan;
Fanfrlik, Jindrich;
Tloustova, Eva;
Horska, Kvetoslava;
Brehova, Petra;
Tryznova, Jana;
Prenosil, Ondrej, Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners. Collect. Czech. Chem. Commun. 2010, 75(12), 1249 - 1257, 10.1135/cccc2010094 .
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