Molecular Formula: C9H15N6O4P
Molecular weight: 302.226961
InChi: InChI=1S/C9H15N6O4P/c1-5(19-4-20(16,17)18)2-15-3-12-6-7(10)13-9(11)14-8(6)15/h3,5H,2,4H2,1H3,(H2,16,17,18)(H4,10,11,13,14)/t5-/m0/s1
InChi Key: LWEKFDHXJHJYGB-YFKPBYRVSA-N
SMILES: c12c(c(nc(n2)N)N)ncn1C[C@@H](OCP(=O)(O)O)C
Chemical Name
(S)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine
(S)-9-[2-(phosphonomethoxy)propyl]-2,6-diamino-9H-purine
(S)-9-[2-(phosphonomethoxy)propyl]-2,6-diaminopurine
(S)-PMPDAP
2,6-diamino-9-[(S)-2-(phosphonomethoxy)propyl]purine
(S)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine
(S)-9-[2-(phosphonomethoxy)propyl]-2,6-diamino-9H-purine
(S)-9-[2-(phosphonomethoxy)propyl]-2,6-diaminopurine
(S)-PMPDAP
2,6-diamino-9-[(S)-2-(phosphonomethoxy)propyl]purine
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dvorakova, Hana
Votruba, Ivan
Masojidkova, Milena
Fanfrlik, Jindrich
Tloustova, Eva
Horska, Kvetoslava
Zidek, Zdenek
Krejcova, Romana
Kmonickova, Eva
Potmesil, Petr
Kmoniekova, Eva
Horska, Kvtoslava
Brehova, Petra
Tryznova, Jana
Prenosil, Ondrej
Vavrova, Katerina
Hrabalek, Alexandr
Skolova, Barbora
Roh, Jaroslav
Diblikova, Denisa
Kopecna, Monika
Holy, Antonin
Dvorakova, Hana
Votruba, Ivan
Masojidkova, Milena
Fanfrlik, Jindrich
Tloustova, Eva
Horska, Kvetoslava
Zidek, Zdenek
Krejcova, Romana
Kmonickova, Eva
Potmesil, Petr
Kmoniekova, Eva
Horska, Kvtoslava
Brehova, Petra
Tryznova, Jana
Prenosil, Ondrej
Vavrova, Katerina
Hrabalek, Alexandr
Skolova, Barbora
Roh, Jaroslav
Diblikova, Denisa
Kopecna, Monika
Articles
Holy, Antonin;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. I. THE STEPWISE APPROACH. Collect. Czech. Chem. Commun. 1995, 60(7), 1196 - 1212, 10.1135/cccc19951196 
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Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL)DERIVATIVES OF PURINE AND PYRIMIDINE BASES. II. THE SYNTHON APPROACH. Collect. Czech. Chem. Commun. 1995, 60(8), 1390 - 1409, 10.1135/cccc19951390 .
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Holy, Antonin;
Votruba, Ivan;
Zidek, Zdenek, Inhibition of Murine Lymphocyte Proliferation by N-Substituted Acyclic Purine Nucleoside Phosphonates. Collect. Czech. Chem. Commun. 1996, 61, S182 - S187.
Holy, Antonin;
Votruba, Ivan;
Horska, Kvetoslava;
Krejcova, Romana, Phosphorylation of purine (phosphonomethoxy)alkyl derivatives by mitochondrial AMP kinase (AK2 type) from L1210 cells. Collect. Czech. Chem. Commun. 2000, 65(10), 1653 - 1668.
Holy, Antonin;
Zidek, Zdenek;
Potmesil, Petr;
Kmoniekova, Eva, Immunobiological activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N-substituted adenines, and 2,6-diaminopurines. Eur. J. Pharmacol. 2003, 475(1-3), 149 - 159, 10.1016/S0014-2999(03)02110-1 .
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Holy, Antonin;
Votruba, Ivan;
Krejcova, Romana;
Horska, Kvtoslava, Interaction of guanine phosphonomethoxyalkyl derivatives with GMP kinase isoenzymes. Biochemical Pharmacology 2000, 60(12), 1907 - 1913, 10.1016/S0006-2952(00)00512-8 .
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Holy, Antonin;
Zidek, Zdenek;
Kmonickova, Eva, Secretion of antiretroviral chemokines by human cells cultured with acyclic nucleoside phosphonates. Eur. J. Pharmacol. 2007, 574(1), 77 - 84, 10.1016/j.ejphar.2007.07.024 .
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Holy, Antonin;
Votruba, Ivan;
Fanfrlik, Jindrich;
Tloustova, Eva;
Horska, Kvetoslava;
Brehova, Petra;
Tryznova, Jana;
Prenosil, Ondrej, Inhibition of human purine nucleoside phosphorylase by tenofovir phosphate congeners. Collect. Czech. Chem. Commun. 2010, 75(12), 1249 - 1257, 10.1135/cccc2010094 .
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