Molecular Formula: C15H27N6O4P
Molecular weight: 386.386441
InChi: InChI=1S/C15H27N6O4P/c1-9(2)24-26(22,25-10(3)4)8-23-11(5)6-21-7-18-12-13(16)19-15(17)20-14(12)21/h7,9-11H,6,8H2,1-5H3,(H4,16,17,19,20)/t11-/m1/s1
InChi Key: LCTZTHXIKCWBOF-LLVKDONJSA-N
SMILES: c12c(c(nc(n2)N)N)ncn1C[C@H](OCP(=O)(OC(C)C)OC(C)C)C
Chemical Name
(R)-9-[2-(phosphonomethoxy)propyl]-2,6-diaminopurine diisopropyl ester
bis(2-propyl) (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine
(R)-9-[2-(phosphonomethoxy)propyl]-2,6-diaminopurine diisopropyl ester
bis(2-propyl) (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Votruba, Ivan
Masojidkova, Milena
Mackman, Richard
Cihlar, Tomas
Bahador, Gina
Janeba, Zlatko
Zidek, Zdenek
Neyts, Johan
Kasicka, Vaclav
Baszczynski, Ondrej
Stepan, George
Prochazkova, Eliska
Sazelova, Petra
Auwerx, Joeri
Kiss, Eleonora
Goris, Nesya
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Votruba, Ivan
Masojidkova, Milena
Mackman, Richard
Cihlar, Tomas
Bahador, Gina
Janeba, Zlatko
Zidek, Zdenek
Neyts, Johan
Kasicka, Vaclav
Baszczynski, Ondrej
Stepan, George
Prochazkova, Eliska
Sazelova, Petra
Auwerx, Joeri
Kiss, Eleonora
Goris, Nesya
Articles
Holy, Antonin;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. I. THE STEPWISE APPROACH. Collect. Czech. Chem. Commun. 1995, 60(7), 1196 - 1212, 10.1135/cccc19951196 
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Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL)DERIVATIVES OF PURINE AND PYRIMIDINE BASES. II. THE SYNTHON APPROACH. Collect. Czech. Chem. Commun. 1995, 60(8), 1390 - 1409, 10.1135/cccc19951390 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George, A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities. European Journal of Medicinal Chemistry 2011, 46(9), 3748 - 3754, 10.1016/j.ejmech.2011.05.040 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Baszczynski, Ondrej;
Prochazkova, Eliska, Microwave-assisted hydrolysis of phosphonate diesters: An efficient protocol for the preparation of phosphonic acids. Green Chemistry 2012, 14(8), 2282 - 2288, 10.1039/c2gc35547g .
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Krecmerova, Marcela;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Neyts, Johan;
Kasicka, Vaclav;
Stepan, George;
Sazelova, Petra;
Auwerx, Joeri;
Kiss, Eleonora;
Goris, Nesya, 9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro. Bioorganic and Medicinal Chemistry 2013, 21(5), 1199 - 1208, 10.1016/j.bmc.2012.12.044 .
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