Molecular Formula: C22H20O2
Molecular weight: 316.393
InChi: InChI=1S/C22H20O2/c1-4-10-18(11-5-1)22(24-17-21-16-23-21,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,21H,16-17H2/t21-/m1/s1
InChi Key: XFSXUCMYFWZRAF-OAQYLSRUSA-N
SMILES: C(c1ccccc1)(c1ccccc1)(c1ccccc1)OC[C@@H]1OC1
Chemical Name
(+)-2-[(triphenylethoxy)methyl]oxirane
(2R)-2-[(trityloxy)methyl]oxirane
(R)-2-[(triphenylethoxy)methyl]oxirane
(R)-tritylglycidol
(R)-[(trityloxy)methyl]oxirane
(S)-1-triphenylmethyl glycidyl ether
(S)-[(trityloxy)methyl]oxirane
(+)-2-[(triphenylethoxy)methyl]oxirane
(2R)-2-[(trityloxy)methyl]oxirane
(R)-2-[(triphenylethoxy)methyl]oxirane
(R)-tritylglycidol
(R)-[(trityloxy)methyl]oxirane
(S)-1-triphenylmethyl glycidyl ether
(S)-[(trityloxy)methyl]oxirane
Authors of compound
Budesinsky, Milos
Krecmerova, Marcela
Holy, Antonin
Jindrich, Jindrich
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Pohl, Radek
Klepetarova, Blanka
Clercq, Erik de
Janeba, Zlatko
Andrei, Graciella
Naesens, Lieve
Pomeisl, Karel
Piskala, Alois
Neyts, Johan
Baszczynski, Ondrej
Krecmerova, Marcela
Holy, Antonin
Jindrich, Jindrich
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Pohl, Radek
Klepetarova, Blanka
Clercq, Erik de
Janeba, Zlatko
Andrei, Graciella
Naesens, Lieve
Pomeisl, Karel
Piskala, Alois
Neyts, Johan
Baszczynski, Ondrej
Articles
Budesinsky, Milos;
Holy, Antonin;
Jindrich, Jindrich;
Dvorakova, Hana;
Masojidkova, Milena;
Balzarini, Jan;
De Clercq, Erik;
Andrei, Graciella, Acyclic nucleotide analogs derived from 8-azapurines: Synthesis and antiviral activity. Journal of Medicinal Chemistry 1996, 39(20), 4073 - 4088, 10.1021/jm960314q .
Holy, Antonin;
Masojidkova, Milena;
Janeba, Zlatko, Transformation of 8-[(2-hydroxyalkyl)sulfanyl]adenines to 6-amino-7H-purin-8(9H)-one derivatives. Collect. Czech. Chem. Commun. 2001, 66(9), 1393 - 1406, 10.1135/cccc20011393 .
Holy, Antonin;
Votruba, Ivan;
Pohl, Radek;
Pomeisl, Karel, Simple transformation of thymine 1-[3-hydroxy-2-(phosphonomethoxy)propyl] derivatives to their 1-[3-fluoro-2-(phosphonomethoxy)propyl] counterparts. Collect. Czech. Chem. Commun. 2005, 70(9), 1465 - 1481, 10.1135/cccc2 .
Holy, Antonin;
Votruba, Ivan;
Pohl, Radek;
Pomeisl, Karel, Syntheses of base and side-chain modified pyrimidine 1-[2- (phosphonomethoxy)propyl] derivatives as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma. Collect. Czech. Chem. Commun. 2006, 71(4), 595 - 624, 10.1135/cccc20060595 .
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Naesens, Lieve;
Piskala, Alois;
Neyts, Johan, Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2- (phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds. Journal of Medicinal Chemistry 2007, 50(5), 1069 - 1077, 10.1021/jm061281+ .
Holy, Antonin;
Votruba, Ivan;
Pohl, Radek;
Pomeisl, Karel, Syntheses of N-substituted thymine acyclic nucleoside phosphonates and a comparison of their inhibitory effect towards thymidine phosphorylase. Bioorganic and Medicinal Chemistry Letters 2008, 18(4), 1364 - 1367, 10.1016/j.bmcl.2008.01.006 .
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Pyrimidine acyclic nucleotide analogues with aromatic substituents in C-5 position. Collect. Czech. Chem. Commun. 2007, 72(7), 927 - 951, 10.1135/cccc20070927 .
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position. Bioorganic and Medicinal Chemistry 2010, 18(1), 387 - 395, 10.1016/j.bmc.2009.10.044 .
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Balzarini, Jan;
Klepetarova, Blanka;
Clercq, Erik de;
Janeba, Zlatko;
Baszczynski, Ondrej, Synthesis and antiviral activity of N-[3-fluoro-2- (phosphonomethoxy)propyl] analogues derived from N-substituted adenines and 2,6-diaminopurines. Bioorganic and Medicinal Chemistry 2011, 19(7), 2114 - 2124, 10.1016/j.bmc.2011.02.050 .