Molecular Formula: C14H24N5O5P
Molecular weight: 373.344621
InChi: InChI=1S/C14H24N5O5P/c1-9(2)23-25(21,24-10(3)4)8-22-6-5-19-7-16-11-12(19)17-14(15)18-13(11)20/h7,9-10H,5-6,8H2,1-4H3,(H3,15,17,18,20)
InChi Key: GDRRARQNRFTRCP-UHFFFAOYSA-N
SMILES: P(=O)(COCCn1c2c(nc1)c(=O)[nH]c(n2)N)(OC(C)C)OC(C)C
Chemical Name
9-[2-[(diisopropoxyphosphoryl)methoxy]ethyl]guanine
Authors of compound
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Mackman, Richard
Cihlar, Tomas
Bahador, Gina
Guenter, Jaroslav
Janeba, Zlatko
Zidek, Zdenek
Baszczynski, Ondrej
Stepan, George
Prochazkova, Eliska
Articles
Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Guenter, Jaroslav,
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.
Journal of Medicinal Chemistry 1999,
42(12), 2064 - 2086,
10.1021/jm9811256 
.
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George,
A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities.
European Journal of Medicinal Chemistry 2011,
46(9), 3748 - 3754,
10.1016/j.ejmech.2011.05.040 .
