Molecular Formula: C13H25N4O5P
Molecular weight: 348.335161
InChi: InChI=1S/C13H25N4O5P/c1-9(2)21-23(18,22-10(3)4)8-19-5-6-20-12-7-11(14)16-13(15)17-12/h7,9-10H,5-6,8H2,1-4H3,(H4,14,15,16,17)
InChi Key: PXPFACYWCXSPRV-UHFFFAOYSA-N
SMILES: P(=O)(OC(C)C)(OC(C)C)COCCOc1nc(nc(c1)N)N
Chemical Name
2,4-diamino-6-[2-(diisopropylphosphorylmethoxy)ethoxy]pyrimidine
Authors of compound
Holy, Antonin
Dracinsky, Martin
Jansa, Petr
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Mackman, Richard
Cihlar, Tomas
Bahador, Gina
Janeba, Zlatko
Zidek, Zdenek
Naesens, Lieve
Baszczynski, Ondrej
Stepan, George
Articles
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Naesens, Lieve,
6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity.
Journal of Medicinal Chemistry 2002,
45(9), 1918 - 1929,
10.1021/jm011095y 
.
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana,
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy) ethoxy]pyrimidines-Acyclic Nucleoside Phosphonate Analogues with Antiviral Activity.
Journal of Medicinal Chemistry 2003,
46(23), 5064 - 5073.
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George,
A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities.
European Journal of Medicinal Chemistry 2011,
46(9), 3748 - 3754,
10.1016/j.ejmech.2011.05.040 .
