Molecular Formula: C8H15N4O5P
Molecular weight: 278.202261
InChi: InChI=1S/C8H15N4O5P/c1-5-6(9)11-8(10)12-7(5)17-3-2-16-4-18(13,14)15/h2-4H2,1H3,(H2,13,14,15)(H4,9,10,11,12)
InChi Key: JSPYZDUIKDWUQG-UHFFFAOYSA-N
SMILES: c1(c(c(nc(n1)N)N)C)OCCOCP(=O)(O)O
Chemical Name
5-methyl-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidine
Authors of compound
Holy, Antonin
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
BALZARINI, Jan, Marie, Rene
DE CLERCQ, Erik, Desire, Alice
Articles
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana,
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy) ethoxy]pyrimidines-Acyclic Nucleoside Phosphonate Analogues with Antiviral Activity.
Journal of Medicinal Chemistry 2003,
46(23), 5064 - 5073.
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana,
Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2- (phosphonomethoxy)ethoxy]pyrimidine and related compounds.
Bioorganic and Medicinal Chemistry 2004,
12(12), 3197 - 3202,
10.1016/j.bmc.2004.04.002 .
Patents
Holy, Antonin;
Hockova, Dana;
BALZARINI, Jan, Marie, Rene;
DE CLERCQ, Erik, Desire, Alice,
PYRIMIDINE COMPOUNDS HAVING PHOSPHONATE GROUPS AS ANTIVIRAL NUCLEOTIDE ANALOGS, WO2004/111064, 2004.