Molecular Formula: C9H13N5O4
Molecular weight: 255.23062
InChi: InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
InChi Key: IRSCQMHQWWYFCW-UHFFFAOYSA-N
SMILES: c12c(c(=O)[nH]c(n2)N)ncn1COC(CO)CO
Chemical Name
2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol
9-[(1,3-dihydroxy-2-propoxy)methyl]guanine
9-[[2-hydroxy-1-(hydroxymethyl)-ethoxy]methyl]guanine
cymevene.(R).
Ganciclovir
gancyclovir
2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol
9-[(1,3-dihydroxy-2-propoxy)methyl]guanine
9-[[2-hydroxy-1-(hydroxymethyl)-ethoxy]methyl]guanine
cymevene.(R).
Ganciclovir
gancyclovir
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Pohl, Radek
Cihlar, Tomas
Naesens, Lieve
Pomeisl, Karel
Naesens
Lenaerts
Andrei
Snoeck
Van Beers
Piskala, Alois
Neyts, Johan
Tichy, Tomas
Brehova, Petra
Laflamme, Genevieve
Hui, Hon
Holy, Antonin
Dracinsky, Martin
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Pohl, Radek
Cihlar, Tomas
Naesens, Lieve
Pomeisl, Karel
Naesens
Lenaerts
Andrei
Snoeck
Van Beers
Piskala, Alois
Neyts, Johan
Tichy, Tomas
Brehova, Petra
Laflamme, Genevieve
Hui, Hon
Articles
Holy, Antonin;
Balzarini, Jan;
De Clercq, Erik;
Naesens;
Lenaerts;
Andrei;
Snoeck;
Van Beers, Antiadenovirus activities of several classes of nucleoside and nucleotide analogues. Antimicrobial Agents and Chemotherapy 2005, 49(3), 1010 - 1016, 10.1128/AAC.49.3.1010-1016.2005 
.
.
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Naesens, Lieve;
Piskala, Alois;
Neyts, Johan, Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2- (phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds. Journal of Medicinal Chemistry 2007, 50(5), 1069 - 1077, 10.1021/jm061281+ .
.
Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Cihlar, Tomas;
Naesens, Lieve;
Pomeisl, Karel;
Neyts, Johan;
Tichy, Tomas;
Brehova, Petra;
Laflamme, Genevieve;
Hui, Hon, Synthesis of ester prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] -2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. Journal of Medicinal Chemistry 2010, 53(19), 6825 - 6837, 10.1021/jm901828c .
.
Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Tichy, Tomas, New prodrugs of Adefovir and Cidofovir. Bioorganic and Medicinal Chemistry 2011, 19(11), 3527 - 3539, 10.1016/j.bmc.2011.04.016 .
.
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Hockova, Dana, Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activity. Bioorganic and Medicinal Chemistry 2011, 19(15), 4445 - 4453, 10.1016/j.bmc.2011.06.045 .
.
Krecmerova, Marcela;
Dracinsky, Martin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Tichy, Tomas, Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety. Eur. J. Med. Chem. 2012, 55, 307 - 314,8, 10.1016/j.ejmech.2012.07.027 .
.
Krecmerova, Marcela;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Pohl, Radek, N-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: Chemistry and antiviral activity. Bioorganic and Medicinal Chemistry 2014, 22(10), 2896 - 2906, 10.1016/j.bmc.2014.03.031 .
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