Molecular Formula: C7H11N4O5P
Molecular weight: 262.159801
InChi: InChI=1S/C7H11N4O5P/c8-6-9-3-11(7(12)10-6)1-5-2-16-17(13,14)4-15-5/h3,5H,1-2,4H2,(H,13,14)(H2,8,10,12)/t5-/m0/s1
InChi Key: ZAFZQDSCZHSXRL-YFKPBYRVSA-N
SMILES: n1(c(=O)nc(nc1)N)C[C@@H]1OCP(=O)(OC1)O
Chemical Name
1-{[(5S)-2-hydroxy-2-oxido-1,4,2-dioxaphosphinan-5-yl]methyl}-5-azacytosine
1-{[(5S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphinan-5-yl]methyl}-5-azacytosine
cHPMP-5-azaC
cyclic HPMP-5-azacytosine
1-{[(5S)-2-hydroxy-2-oxido-1,4,2-dioxaphosphinan-5-yl]methyl}-5-azacytosine
1-{[(5S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphinan-5-yl]methyl}-5-azacytosine
cHPMP-5-azaC
cyclic HPMP-5-azacytosine
Articles
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Lebeau, Ilya, Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains. Antimicrobial Agents and Chemotherapy 2007, 51(6), 2268 - 2273, 10.1128/AAC.01422-06 .
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Duraffour, Sophie;
Van Den Oord, Joost;
De Vos, Rita;
Crance, Jean-Marc;
Garin, Daniel, Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models. Antimicrobial Agents and Chemotherapy 2007, 51(12), 4410 - 4419, 10.1128/AAC.00838-07 .
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Naesens, Lieve;
Neyts, Johan, Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5- azacytosine: Synthesis and antiviral activity. Journal of Medicinal Chemistry 2007, 50(23), 5765 - 5772, 10.1021/jm0707166 .
Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin, Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy. Bioorganic and Medicinal Chemistry 2008, 16(14), 6778 - 6782, 10.1016/j.bmc.2008.05.058 .
Krecmerova, Marcela;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Pohl, Radek, N-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: Chemistry and antiviral activity. Bioorganic and Medicinal Chemistry 2014, 22(10), 2896 - 2906, 10.1016/j.bmc.2014.03.031 .