Molecular Formula: C25H47N4O6P
Molecular weight: 530.637641
InChi: InChI=1S/C25H47N4O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-32-17-18-34-36(31)22-33-23(20-35-36)19-29-21-27-24(26)28-25(29)30/h21,23H,2-20,22H2,1H3,(H2,26,28,30)/t23-,36?/m0/s1
InChi Key: JIKMMMSHZOKJCA-IRUXJXNPSA-N
SMILES: P1(=O)(OC[C@@H](OC1)Cn1c(=O)nc(nc1)N)OCCOCCCCCCCCCCCCCCCC
Chemical Name
HDE-cHPMP-5-azaC
hexadecyloxyethyl ester of 1-{[(5S)-2-hydroxy-2-oxido-1,4,2-dioxaphosphinan-5-yl]methyl}-5-azacytosine
hexadecyloxyethyl ester of cHPMP-5-azaC
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Pohl, Radek
Naesens, Lieve
Piskala, Alois
Neyts, Johan
Lebeau, Ilya
Duraffour, Sophie
Van Den Oord, Joost
De Vos, Rita
Crance, Jean-Marc
Garin, Daniel
Articles
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Lebeau, Ilya,
Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains.
Antimicrobial Agents and Chemotherapy 2007,
51(6), 2268 - 2273,
10.1128/AAC.01422-06 .
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Duraffour, Sophie;
Van Den Oord, Joost;
De Vos, Rita;
Crance, Jean-Marc;
Garin, Daniel,
Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models.
Antimicrobial Agents and Chemotherapy 2007,
51(12), 4410 - 4419,
10.1128/AAC.00838-07 .
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Naesens, Lieve;
Neyts, Johan,
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5- azacytosine: Synthesis and antiviral activity.
Journal of Medicinal Chemistry 2007,
50(23), 5765 - 5772,
10.1021/jm0707166 .
Patents
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Naesens, Lieve;
Piskala, Alois;
Neyts, Johan,
AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS, WO2007/65231, 2007.