Molecular Formula: C15H31N6O4PSi2
Molecular weight: 446.589201
InChi: InChI=1S/C15H31N6O4PSi2/c1-11(8-21-9-18-12-13(16)19-15(17)20-14(12)21)23-10-26(22,24-27(2,3)4)25-28(5,6)7/h9,11H,8,10H2,1-7H3,(H4,16,17,19,20)/t11-/m1/s1
InChi Key: YCIYKJFNFOUYDP-LLVKDONJSA-N
SMILES: c12c(n(cn2)C[C@H](OCP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)C)nc(nc1N)N
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Jansa, Petr
Votruba, Ivan
Mackman, Richard
Cihlar, Tomas
Bahador, Gina
Janeba, Zlatko
Zidek, Zdenek
Neyts, Johan
Kasicka, Vaclav
Baszczynski, Ondrej
Stepan, George
Sazelova, Petra
Auwerx, Joeri
Kiss, Eleonora
Goris, Nesya
Articles
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George,
A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities.
European Journal of Medicinal Chemistry 2011,
46(9), 3748 - 3754,
10.1016/j.ejmech.2011.05.040 
.
Krecmerova, Marcela;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Neyts, Johan;
Kasicka, Vaclav;
Stepan, George;
Sazelova, Petra;
Auwerx, Joeri;
Kiss, Eleonora;
Goris, Nesya,
9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro.
Bioorganic and Medicinal Chemistry 2013,
21(5), 1199 - 1208,
10.1016/j.bmc.2012.12.044 .
