Molecular Formula: C6H13O3P
Molecular weight: 164.139381
InChi: InChI=1S/C6H13O3P/c1-4-8-10(7,6-3)9-5-2/h6H,3-5H2,1-2H3
InChi Key: DREPONDJUKIQLX-UHFFFAOYSA-N
SMILES: P(=O)(OCC)(OCC)C=C
Chemical Name
(EtO)2P(O)CH=CH2
CH2=CH-P(O)(OEt)2
diethyl vinyl phosphonate
diethyl vinylphosphonate
diethylvinylphosphonate
vinyldiethylphosphonate
vinylphosphonic acid diethyl ester
Authors of compound
Holy, Antonin
Dracinsky, Martin
Jansa, Petr
Cesnek, Michal
Hockova, Dana
Slavetinska, Lenka
Janeba, Zlatko
Naesens, Lieve
Vrbkova, Silvie
Keough, Dianne T.
De Jersey, John
Guddat, Luke W.
Tichy, Tomas
Jersey, John de
Baszczynski, Ondrej
Spacek, Petr
Wang, Tzu-Hsuan
Edstein, Michael D.
Chavchich, Marina
Articles
Holy, Antonin;
Dracinsky, Martin;
Cesnek, Michal;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W.;
Jersey, John de;
Baszczynski, Ondrej,
Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: Evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.
Bioorganic and Medicinal Chemistry 2012,
20(2), 1076 - 1089,
10.1016/j.bmc.2011.11.034 
.
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
Guddat, Luke W.;
Baszczynski, Ondrej,
The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.
European Journal of Medicinal Chemistry 2013,
67, 81 - 89,
10.1016/j.ejmech.2013.06.032 .
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Wang, Tzu-Hsuan,
Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases.
Journal of Medicinal Chemistry 2012,
55(13), 6209 - 6223,
10.1021/jm300662d .
Hockova, Dana;
Slavetinska, Lenka;
Janeba, Zlatko;
Naesens, Lieve;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Tichy, Tomas;
Spacek, Petr;
Wang, Tzu-Hsuan;
Edstein, Michael D.;
Chavchich, Marina,
Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity.
Journal of Medicinal Chemistry 2013,
56(6), 2513 - 2526,
10.1021/jm301893b .
