Molecular Formula: C9H13N4O6P
Molecular weight: 304.196481
InChi: InChI=1S/C9H13N4O6P/c14-6(2-19-5-20(16,17)18)1-13-4-12-7-8(13)10-3-11-9(7)15/h3-4,6,14H,1-2,5H2,(H,10,11,15)(H2,16,17,18)
InChi Key: NUPKGLREIXDUDS-UHFFFAOYSA-N
SMILES: c12c(c(=O)[nH]cn2)ncn1CC(COCP(=O)(O)O)O
Chemical Name
9-[2-hydroxy-3-(phosphonomethoxy)propyl]hypoxanthine
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Hockova, Dana
Vrbkova, Silvie
Keough, Dianne T.
De Jersey, John
Guddat, Luke W.
Rejman, Dominik
Spacek, Petr
Eng, Wai Soon
Jans, Harmen
West, Nicholas P.
Naesens, Lieve M.J.
Articles
Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W.,
Synthesis of purine N-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents.
Bioorganic and Medicinal Chemistry 2012,
20(3), 1222 - 1230,
10.1016/j.bmc.2011.12.034 .
Krecmerova, Marcela;
Hockova, Dana;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Rejman, Dominik;
Spacek, Petr;
Eng, Wai Soon;
Jans, Harmen;
West, Nicholas P.;
Naesens, Lieve M.J.,
Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: Potential for new antibacterial agents.
Journal of Medicinal Chemistry 2013,
56(17), 6967 - 6984,
10.1021/jm400779n .