Molecular Formula: C5H11N
Molecular weight: 85.14754
InChi: InChI=1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2
InChi Key: NQRYJNQNLNOLGT-UHFFFAOYSA-N
SMILES: N1CCCCC1
Chemical Name
Azacyclohexane
cyclohexylamine
hexahydropyridine
indacene
Pi
Pip
piperidine
Azacyclohexane
cyclohexylamine
hexahydropyridine
indacene
Pi
Pip
piperidine
Authors of compound
Bures, Filip
Pytela, Oldrich
Ludwig, Miroslav
Bernd Schweizer
May, Joshua C.
Boudon, Corinne
Gisselbrecht, Jean-Paul
Gross, Maurice
Biaggio, Ivan
Diederich, Francois
Hrdina, Radim
Drabina, Pavel
Zima, Vitezslav
Krecmerova, Marcela
Holy, Antonin
Parik, Patrik
Svoboda, Jiri
Sedlak, Milos
Lansky, Vaclav
Saman, David
Zavada, Jiri
Stary, Ivo
Hocek, Michal
Votruba, Ivan
Kavalek, Jaromir
Imramovsky, Ales
Potacek, Milan
Masojidkova, Milena
Stara, Irena G.
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Hasnik, Zbynek
Stefko, Martin
Tloustova, Eva
Tloust'Ova, Eva
Hrebabecky, Hubert
Horska, Kveta
Nencka, Radim
Oliveira-Campos, Ana M.F.
Rodrigues, Ligia M.
Esteves, Ana P.
Silva, Marilia E.
Jampilek, Josef
Pesko, Matus
Kralova, Katarina
Gonec, Tomas
Bobal, Pavel
Sujan, Josef
Guo, Jiahui
Pavlacka, Lenka
Vesely, Libor
Kreckova, Eva
Kos, Jiri
Coffey, Aidan
Kollar, Peter
Placek, Lukas
Fiedler, Pavel
Vecera, Miroslav
Paleta, Oldrich
Kvicala, Jaroslav
Dolensky, Bohumil
Palecek, Jiri
Dlouha, Ivona
Bednarova, Iva
Mazal, Ctibor
Jonas, Jaroslav
Jurka, Zdenek
Necas, Marek
Dostal, Jiri
Nechvatal, Miloslav
Man, Stanislav
Zachova, Hana
Pulst, M.
Potacek, M.
Kollarovic, Adrian
Teply, Filip
Sehnal, Petr
Krausova, Zuzana
Bondzic, Bojan P.
Chercheja, Serghei
Eilbracht, Peter
Pytela, Oldrich
Ludwig, Miroslav
Bernd Schweizer
May, Joshua C.
Boudon, Corinne
Gisselbrecht, Jean-Paul
Gross, Maurice
Biaggio, Ivan
Diederich, Francois
Hrdina, Radim
Drabina, Pavel
Zima, Vitezslav
Krecmerova, Marcela
Holy, Antonin
Parik, Patrik
Svoboda, Jiri
Sedlak, Milos
Lansky, Vaclav
Saman, David
Zavada, Jiri
Stary, Ivo
Hocek, Michal
Votruba, Ivan
Kavalek, Jaromir
Imramovsky, Ales
Potacek, Milan
Masojidkova, Milena
Stara, Irena G.
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Hasnik, Zbynek
Stefko, Martin
Tloustova, Eva
Tloust'Ova, Eva
Hrebabecky, Hubert
Horska, Kveta
Nencka, Radim
Oliveira-Campos, Ana M.F.
Rodrigues, Ligia M.
Esteves, Ana P.
Silva, Marilia E.
Jampilek, Josef
Pesko, Matus
Kralova, Katarina
Gonec, Tomas
Bobal, Pavel
Sujan, Josef
Guo, Jiahui
Pavlacka, Lenka
Vesely, Libor
Kreckova, Eva
Kos, Jiri
Coffey, Aidan
Kollar, Peter
Placek, Lukas
Fiedler, Pavel
Vecera, Miroslav
Paleta, Oldrich
Kvicala, Jaroslav
Dolensky, Bohumil
Palecek, Jiri
Dlouha, Ivona
Bednarova, Iva
Mazal, Ctibor
Jonas, Jaroslav
Jurka, Zdenek
Necas, Marek
Dostal, Jiri
Nechvatal, Miloslav
Man, Stanislav
Zachova, Hana
Pulst, M.
Potacek, M.
Kollarovic, Adrian
Teply, Filip
Sehnal, Petr
Krausova, Zuzana
Bondzic, Bojan P.
Chercheja, Serghei
Eilbracht, Peter
Articles
Bures, Filip;
Bernd Schweizer;
May, Joshua C.;
Boudon, Corinne;
Gisselbrecht, Jean-Paul;
Gross, Maurice;
Biaggio, Ivan;
Diederich, Francois, Property tuning in charge-transfer chromophores by systematic modulation of the spacer between donor and acceptor. Chemistry - A European Journal 2007, 13(19), 5378 - 5387, 10.1002/chem.200601735 
.
.
Drabina, Pavel;
Svoboda, Jiri;
Sedlak, Milos;
Lansky, Vaclav, Synthesis and characterization of substituted (benzo[b]thiophen-2-yl)-4- methyl-4,5-dihydro-1H-imidazol-5-ones. Journal of Heterocyclic Chemistry 2008, 45(3), 859 - 863, 10.1002/jhet.5570450334 .
.
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Kuchar, Martin, Synthesis of purines bearing functionalized C-substituents by the conjugate addition of nucleophiles to 6-vinylpurines and 6-ethynylpurines. European Journal of Organic Chemistry 2006(22), 5083 - 5098, 10.1002/ejoc.200600545 .
.
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Shih, I-hung;
Mabery, Eric;
Mackman, Richard;
Kuchar, Martin, Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(3), 1400 - 1424, 10.1016/j.bmc.2007.10.063 .
.
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Silhar, Peter;
Shih, I-hung;
Mabery, Eric;
Mackman, Richard, Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(5), 2329 - 2366, 10.1016/j.bmc.2007.11.067 .
.
Hocek, Michal;
Pohl, Radek;
Stefko, Martin, Synthesis of benzamide-C-ribonucleosides by Pd-catalyzed aminocarbonylations. Tetrahedron 2009, 65(23), 4471 - 4483, 10.1016/j.tet.2009.04.006 .
.
Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Hasnik, Zbynek, Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)-and 6-(carbamoylmethyl)purines. Collect. Czech. Chem. Commun. 2009, 74(7-8), 1035 - 1059, 10.1135/cccc2009042 .
.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Tloustova, Eva, Synthesis and cytostatic activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N-substituted adenines, 2,6-diaminopurines and related compounds. Collect. Czech. Chem. Commun. 2001, 66(10), 1545 - 1592.
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Synthesis of N- and N-[2-hydroxy-3- (phosphonomethoxy)-propyl] derivatives of N-substituted adenines, 2,6-diaminopurines and related compounds. Collect. Czech. Chem. Commun. 2004, 69(10), 1889 - 1913, 10.1135/cccc20041889 .
.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Tloust'Ova, Eva;
Hrebabecky, Hubert;
Horska, Kveta;
Nencka, Radim, Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase. Bioorganic and Medicinal Chemistry Letters 2006, 16(5), 1335 - 1337, 10.1016/j.bmcl.2005.11.050 .
.
Hrdina, Radim;
Oliveira-Campos, Ana M.F.;
Rodrigues, Ligia M.;
Esteves, Ana P.;
Silva, Marilia E., Aza-Michael reactions with vinyl sulfones and Amberlyst-15 as catalyst. Tetrahedron Letters 2007, 48(51), 9040 - 9043, 10.1016/j.tetlet.2007.10.077 .
.
Imramovsky, Ales;
Jampilek, Josef;
Pesko, Matus;
Kralova, Katarina;
Gonec, Tomas;
Bobal, Pavel;
Sujan, Josef;
Guo, Jiahui;
Pavlacka, Lenka;
Vesely, Libor;
Kreckova, Eva;
Kos, Jiri;
Coffey, Aidan;
Kollar, Peter;
Placek, Lukas, Investigating the spectrum of biological activity of substituted quinoline-2-carboxamides and their isosteres. Molecules 2012, 17(1), 613 - 644, 10.3390/molecules17010613 .
.
Pytela, Oldrich;
Zima, Vitezslav;
Kavalek, Jaromir;
Vecera, Miroslav, REACTIVITY OF NUCLEOPHILES IN DIMETHYL SULFOXIDE AND ITS COMPARISON WITH NUCLEOPHILIC REACTIVITY IN PROTIC MEDIUM. Collect. Czech. Chem. Commun. 1989, 54(10), 2715 - 2720.
Paleta, Oldrich;
Kvicala, Jaroslav;
Dlouha, Ivona, Reactivity study of 1,1,2,4,4,5,7,7,8,8,9,9,-tridecafluoro-5- trifluoromethyl-3,6-dioxanon-1-ene in nucleophilic reactions: Fluorination properties of secondary amine adducts. Journal of Fluorine Chemistry 2002, 117(2), 149 - 159, 10.1016/S0022-1139(02)00159-8 .
.
Paleta, Oldrich;
Kvicala, Jaroslav;
Dolensky, Bohumil;
Palecek, Jiri, New nucleophilic rearrangement in the mechanism of the three-component domino cyclisation affording fluoroalkylated (pyrrolo)quinazolines. Journal of Fluorine Chemistry 2014, 157, 1 - 11, 10.1016/j.jfluchem.2013.10.017 .
.
Ludwig, Miroslav;
Parik, Patrik;
Bednarova, Iva, Effect of medium on acid-catalyzed decomposition of N-(phenylazo)-substituted nitrogen heterocycles. Collect. Czech. Chem. Commun. 1999, 64(1), 1654 - 1672.
Mazal, Ctibor;
Jonas, Jaroslav;
Jurka, Zdenek, TRANSFORMATIONS OF 3-(METHYLENE)DIHYDRO-2(3H)-FURANONE DERIVATIVES. Collect. Czech. Chem. Commun. 1984, 49(11), 2509 - 2519.
Mazal, Ctibor;
Jonas, Jaroslav, NUCLEOPHILIC VINYLIC SUBSTITUTION ON α-TOSYLOXYMETHYLLENE LACTONES. Collect. Czech. Chem. Commun. 1993, 58(7), 1607 - 1623, 10.1135/cccc19931607 .
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Potacek, Milan;
Dostal, Jiri;
Nechvatal, Miloslav, REACTION OF 5-METHYLPHENANTHRIDINIUM IODIDE WITH NUCLEOPHILES AND REACTION PRODUCTS CONVERSION. Collect. Czech. Chem. Commun. 1993, 58(2), 395 - 403, 10.1135/cccc19930395 .
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Potacek, Milan;
Necas, Marek;
Man, Stanislav;
Zachova, Hana, Fused tetraeyclic heterocycles by thermally initiated intramolecular criss-cross cycloaddition of 3-substituted homoallenylaldazines. European Journal of Organic Chemistry 2005(12), 2548 - 2557, 10.1002/ejoc.200400814 .
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Pulst, M.;
Potacek, M., Contributions to Synthesis of Enaminothioketones. J. Prakt. Chem. (Leipzig) 1988, 330(4), 665 - 670.
Pytela, Oldrich;
Zima, Vitezslav;
Vecera, Miroslav, A STUDY OF NUCLEOPHILICITY IN SELECTED SYSTEMS. Collect. Czech. Chem. Commun. 1988, 53(4), 814 - 821.
Zavada, Jiri;
Stary, Ivo;
Stara, Irena G., Nucleophilic Cleavage of 4,5-Dihydro-3H-dinaphth<2,1-c:1',2'-e>azepinium Quaternary Salts. A Convenient Approach to New Axially Dissymmetric and Axially Asymmetric Ligands. Journal of Organic Chemistry 1992, 57(25), 6966 - 6969, 10.1021/jo00051a053 .
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Saman, David;
Stary, Ivo;
Stara, Irena G.;
Fiedler, Pavel;
Kollarovic, Adrian;
Teply, Filip, Coupling reactions of ortho-substituted aryl halides with alkynes. The synthesis of functionalized 1-naphthyl-, 1-(1-naphthyl)-2-phenyl-, and 1,2- bis(1-naphthyl)acetylenes. Tetrahedron 1998, 54(37), 11209 - 11234.
Saman, David;
Stary, Ivo;
Stara, Irena G.;
Fiedler, Pavel;
Kollarovic, Adrian;
Teply, Filip, Coupling reactions of ortho-substituted halobenzenes with alkynes. The synthesis of phenylacetylenes and symmetrical or unsymmetrical 1,2-diphenylacetylenes. Collect. Czech. Chem. Commun. 1999, 64(4), 649 - 672.
Saman, David;
Stary, Ivo;
Stara, Irena G.;
Sehnal, Petr;
Krausova, Zuzana;
Bondzic, Bojan P.;
Chercheja, Serghei;
Eilbracht, Peter, Helicene-based phosphite ligands in asymmetric transition-metal catalysis: Exploring Rh-catalyzed hydroformylation and Ir-catalyzed allylic amination. European Journal of Organic Chemistry 2011(20-21), 3849 - 3857, 10.1002/ejoc.201100259 .
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