Detail of compound @ czechem

Molecular Formula: C₄H₉NO

Molecular weight: 87.12036

InChi: InChI=1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2

InChi Key: YNAVUWVOSKDBBP-UHFFFAOYSA-N

SMILES: O1CCNCC1

Chemical Name
anhydrous morpholine
CH2-Morpholine
dihydro-1,4-oxazine
morpholine
perhydro-1,4-oxazine
tetrahydro-1,4-oxazine
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External Links
PubChem

Authors of compound

Cisarova, Ivana
Pytela, Oldrich
Ludwig, Miroslav
Ludvik, Jiri
Padelkova, Zdenka
Zima, Vitezslav
Budesinsky, Milos
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Parik, Patrik
Hodacova, Jana
Stibor, Ivan
Machacek, Vladimir
Simunek, Petr
Svobodova, Marketa
Broz, Bretislav
Dvorak, Dalimil
Saman, David
Arnold, Zdenek
Zavada, Jiri
Stary, Ivo
Hocek, Michal
Stepnicka, Petr
Tobrman, Tomas
Meca, Ludek
Kotek, Vladislav
Chudikova, Nadezda
Votruba, Ivan
Maryska, Michal
Kavalek, Jaromir
Sterba, Vojeslav
Mindl, Jaromir
Bertolasi, Valerio
Imramovsky, Ales
Potacek, Milan
Masojidkova, Milena
Stara, Irena G.
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Otmar, Miroslav
Stefko, Martin
Tloustova, Eva
Tloust'Ova, Eva
Beer, Paul D.
Hesek, Dusan
Stokes, Sally E.
Hazelwood, Clare
Belohradsky, Martin
Holy, Petr
Tichy, Milos
Rosenberg, Ivan
Hrebabecky, Hubert
Horska, Kveta
Dolakova, Petra
Nencka, Radim
Solinova, Veronika
Kasicka, Vaclav
Pechar, Michal
Braunova, Alena
Subr, Vladimir
Ulbrich, Karel
Vinsova, Jarmila
Polanc, Slovenko
Kocevar, Marijan
Jampilek, Josef
Reckova, Zuzana
Kaustova, Jarmila
Fiedler, Pavel
Vecera, Miroslav
Bednarova, Iva
Mazal, Ctibor
Jonas, Jaroslav
Jurka, Zdenek
Necas, Marek
Dostal, Jiri
Nechvatal, Miloslav
Man, Stanislav
Zachova, Hana
Pulst, M.
Potacek, M.
Kralikova, Sarka
Budesinky, Milos
Sehnal, Petr
Krausova, Zuzana
Bondzic, Bojan P.
Chercheja, Serghei
Eilbracht, Peter
Klicnar, Jiri
Kaderabek, Vladimir

Articles

Dvorak, Dalimil; Arnold, Zdenek, REACTION OF ARYLMETHYLENEMALONALDEHYDES WITH SOME NUCLEOPHILES. Collect. Czech. Chem. Commun. 1987, 52(11), 2699 - 2709.

Cisarova, Ivana; Ludvik, Jiri; Dvorak, Dalimil; Stepnicka, Petr; Meca, Ludek, Synthesis, structures, and electrochemistry of group 6 aminocarbenes with a P-chelating 1′-(diphenylphosphino)ferrocenyl substituent. Organometallics 2004, 23(11), 2541 - 2551, 10.1021/om040007f

Dvorak, Dalimil; Tobrman, Tomas; Kotek, Vladislav; Chudikova, Nadezda; Maryska, Michal, Regioselective and efficient synthesis of N -substituted adenines, guanines, and 6-mercaptopurines. Monatshefte fur Chemie 2013, 144(4), 501 - 507, 10.1007/s00706-012-0899-x

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Kuchar, Martin, Synthesis of purines bearing functionalized C-substituents by the conjugate addition of nucleophiles to 6-vinylpurines and 6-ethynylpurines. European Journal of Organic Chemistry 2006(22), 5083 - 5098, 10.1002/ejoc.200600545

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Shih, I-hung; Mabery, Eric; Mackman, Richard; Kuchar, Martin, Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(3), 1400 - 1424, 10.1016/j.bmc.2007.10.063

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Silhar, Peter; Shih, I-hung; Mabery, Eric; Mackman, Richard, Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(5), 2329 - 2366, 10.1016/j.bmc.2007.11.067

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Klepetarova, Blanka; Kuchar, Martin, Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations. Organic and Biomolecular Chemistry 2008, 6(13), 2377 - 2387, 10.1039/b802833h

Hocek, Michal; Pohl, Radek; Stefko, Martin, Synthesis of benzamide-C-ribonucleosides by Pd-catalyzed aminocarbonylations. Tetrahedron 2009, 65(23), 4471 - 4483, 10.1016/j.tet.2009.04.006

Hodacova, Jana; Beer, Paul D.; Hesek, Dusan; Stokes, Sally E., Acyclic Redox Responsive Anion Receptors containing Amide Linked Cobalticinium Moieties. J. Chem. Soc., Chem. Commun. 1992(3), 270 - 272, 10.1039/c39920000270

Hodacova, Jana; Beer, Paul D.; Hesek, Dusan; Stokes, Sally E.; Hazelwood, Clare, Anion Recognition by Acyclic Redox-responsive Amide-linked Cobaltocenium Receptors. J. Chem. Soc., Dalton Trans. (1972-1999) 1993(8), 1327 - 1332.

Holy, Antonin; Rosenberg, Ivan, SYNTHESIS OF POTENTIAL PRODRUGS AND METABOLITES OF 9-(S)-(3-HYDROXY-2-PHOSPHONYLMETHOXYPROPYL)ADENINE. Collect. Czech. Chem. Commun. 1987, 52(11), 2792 - 2800.

Holy, Antonin; Rosenberg, Ivan, SYNTHESIS OF 9-(2-PHOSPHONYLMETHOXYETHYL)ADENINE AND RELATED COMPOUNDS. Collect. Czech. Chem. Commun. 1987, 52(11), 2801 - 2809.

Holy, Antonin; Rosenberg, Ivan, PREPARATION OF 5'-O-PHOSPHONYLMETHYL ANALOGUES OF NUCLEOSIDE-5'-PHOSPHATES, 5'-DIPHOSPHATES AND 5'-TRIPHOSPHATES. Collect. Czech. Chem. Commun. 1982, 47(12), 3447 - 3463.

Holy, Antonin; Votruba, Ivan; Masojidkova, Milena; Otmar, Miroslav, An alternative synthesis of HPMPC and HPMPA diphosphoryl derivatives. Collect. Czech. Chem. Commun. 2001, 66(3), 500 - 506, 10.1135/cccc20010500

Holy, Antonin; Votruba, Ivan; Masojidkova, Milena; Tloustova, Eva, Synthesis and cytostatic activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N-substituted adenines, 2,6-diaminopurines and related compounds. Collect. Czech. Chem. Commun. 2001, 66(10), 1545 - 1592.

Budesinsky, Milos; Krecmerova, Marcela; Holy, Antonin; Masojidkova, Milena, Synthesis of optically active N-alkyl derivatives of (R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds. Collect. Czech. Chem. Commun. 2003, 68(5), 931 - 950, 10.1135/cccc20030931

Holy, Antonin; Votruba, Ivan; Masojidkova, Milena; Tloust'Ova, Eva; Hrebabecky, Hubert; Horska, Kveta; Nencka, Radim, Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase. Bioorganic and Medicinal Chemistry Letters 2006, 16(5), 1335 - 1337, 10.1016/j.bmcl.2005.11.050

Holy, Antonin; Pechar, Michal; Braunova, Alena; Subr, Vladimir; Ulbrich, Karel, Polymemc conjugates of 9-[2-(phosphonomethoxy)ethyl]purine with potential antiviral and cytostatic activity. Collect. Czech. Chem. Commun. 2006, 71(8), 1211 - 1220, 10.1135/cccc20061211

Holy, Antonin; Dracinsky, Martin; Masojidkova, Milena; Dolakova, Petra; Solinova, Veronika; Kasicka, Vaclav, Acyclic nucleoside bisphosphonates: Synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines. European Journal of Medicinal Chemistry 2009, 44(6), 2408 - 2424, 10.1016/j.ejmech.2008.09.031

Imramovsky, Ales; Vinsova, Jarmila; Polanc, Slovenko; Kocevar, Marijan; Jampilek, Josef; Reckova, Zuzana; Kaustova, Jarmila, A new modification of anti-tubercular active molecules. Bioorganic and Medicinal Chemistry 2007, 15(7), 2551 - 2559, 10.1016/j.bmc.2007.01.051

Pytela, Oldrich; Zima, Vitezslav; Kavalek, Jaromir; Vecera, Miroslav, REACTIVITY OF NUCLEOPHILES IN DIMETHYL SULFOXIDE AND ITS COMPARISON WITH NUCLEOPHILIC REACTIVITY IN PROTIC MEDIUM. Collect. Czech. Chem. Commun. 1989, 54(10), 2715 - 2720.

Ludwig, Miroslav; Parik, Patrik; Bednarova, Iva, Effect of medium on acid-catalyzed decomposition of N-(phenylazo)-substituted nitrogen heterocycles. Collect. Czech. Chem. Commun. 1999, 64(1), 1654 - 1672.

Machacek, Vladimir; Simunek, Petr; Svobodova, Marketa; Bertolasi, Valerio, Facile and straightforward method leading to substituted 4-amino-1-arylpyrazoles. Synthesis 2008(11), 1761 - 1766, 10.1055/s-2008-1067042

Mazal, Ctibor; Jonas, Jaroslav; Jurka, Zdenek, TRANSFORMATIONS OF 3-(METHYLENE)DIHYDRO-2(3H)-FURANONE DERIVATIVES. Collect. Czech. Chem. Commun. 1984, 49(11), 2509 - 2519.

Mazal, Ctibor; Jonas, Jaroslav, NUCLEOPHILIC VINYLIC SUBSTITUTION ON α-TOSYLOXYMETHYLLENE LACTONES. Collect. Czech. Chem. Commun. 1993, 58(7), 1607 - 1623, 10.1135/cccc19931607

Potacek, Milan; Dostal, Jiri; Nechvatal, Miloslav, REACTION OF 5-METHYLPHENANTHRIDINIUM IODIDE WITH NUCLEOPHILES AND REACTION PRODUCTS CONVERSION. Collect. Czech. Chem. Commun. 1993, 58(2), 395 - 403, 10.1135/cccc19930395

Potacek, Milan; Necas, Marek; Man, Stanislav; Zachova, Hana, Fused tetraeyclic heterocycles by thermally initiated intramolecular criss-cross cycloaddition of 3-substituted homoallenylaldazines. European Journal of Organic Chemistry 2005(12), 2548 - 2557, 10.1002/ejoc.200400814

Pulst, M.; Potacek, M., Contributions to Synthesis of Enaminothioketones. J. Prakt. Chem. (Leipzig) 1988, 330(4), 665 - 670.

Pytela, Oldrich; Zima, Vitezslav; Vecera, Miroslav, A STUDY OF NUCLEOPHILICITY IN SELECTED SYSTEMS. Collect. Czech. Chem. Commun. 1988, 53(4), 814 - 821.

Masojidkova, Milena; Rosenberg, Ivan; Kralikova, Sarka; Budesinky, Milos, Nucleoside 5′-C-phosphonates: reactivity of the α-hydroxyphosphonate moiety. Tetrahedron 2006, 62(20), 4917 - 4932, 10.1016/j.tet.2006.03.008

Padelkova, Zdenka; Simunek, Petr; Broz, Bretislav; Bertolasi, Valerio, A simple new hydrazine-free synthesis of methyl 1,4,5-trisubstituted 1H-pyrazole-3-carboxylates. Monatshefte fur Chemie 2013, 144(7), 1013 - 1019, 10.1007/s00706-013-0962-2

Zavada, Jiri; Stary, Ivo; Stara, Irena G., Nucleophilic Cleavage of 4,5-Dihydro-3H-dinaphth<2,1-c:1',2'-e>azepinium Quaternary Salts. A Convenient Approach to New Axially Dissymmetric and Axially Asymmetric Ligands. Journal of Organic Chemistry 1992, 57(25), 6966 - 6969, 10.1021/jo00051a053

Zavada, Jiri; Stary, Ivo; Stara, Irena G., OPTICALLY PURE (S)- AND (R)-4,5-DIHYDRO-3H-4-METHYLDINAPHTH<2,1-c;1',2'-e>AZEPINES. APPLICATION TO THE SYNTHESIS OF NEW BIDENTATE LIGANDS WITH AXIAL ASYMMETRY. Tetrahedron Asymmetry 1992, 3(11), 1365 - 1368, 10.1016/0957-4166(92)80007-J

Zavada, Jiri; Stary, Ivo; Stara, Irena G.; Tichy, Milos; Fiedler, Pavel, Nucleophilic Attack on 4,5-Dihydro-4-alkyl-3H-dinaphtho<2,1-c:1',2'-e>thiepinium Salts. A Convenient Approach to New 2,2'-Bidentate 1,1'-Binaphthalene Ligands with Sulfur Donor Atoms. Journal of Organic Chemistry 1994, 59(6), 1326 - 1332, 10.1021/jo00085a021

Saman, David; Stary, Ivo; Stara, Irena G.; Sehnal, Petr; Krausova, Zuzana; Bondzic, Bojan P.; Chercheja, Serghei; Eilbracht, Peter, Helicene-based phosphite ligands in asymmetric transition-metal catalysis: Exploring Rh-catalyzed hydroformylation and Ir-catalyzed allylic amination. European Journal of Organic Chemistry 2011(20-21), 3849 - 3857, 10.1002/ejoc.201100259

Sterba, Vojeslav; Mindl, Jaromir; Klicnar, Jiri; Kaderabek, Vladimir, KINETICS AND MECHANISM OF HYDROLYSIS OF BENZHYDRYL N-ARYLTHIOCARBAMATES AND STUDY OF THEIR IR SPECTRA. Collect. Czech. Chem. Commun. 1984, 49(7), 1577 - 1591.

Stibor, Ivan; Zavada, Jiri; Belohradsky, Martin; Holy, Petr, A VERSATILE SYNTHESIS OF OLIGOCROWN COMPOUNDS WITH HYDROXYL GROUPS AT THE HINGE. Collect. Czech. Chem. Commun. 1987, 52(12), 2961 - 2970.