Molecular Formula: C10H11ClN4O
Molecular weight: 238.67354
InChi: InChI=1S/C10H11ClN4O/c11-9-8-10(13-5-12-9)15(6-14-8)7-3-1-2-4-16-7/h5-7H,1-4H2
InChi Key: QSTASPNCKDPSAH-UHFFFAOYSA-N
SMILES: n1(c2c(nc1)c(ncn2)Cl)C1OCCCC1
Chemical Name
6-chloro-9-(tetrahydro-2-pyranyl)purine
6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
6-chloro-9-(tetrahydro-pyran-2-yl)-9H-purine
6-chloro-9-(tetrahydropyran-2-yl)-9H-purine
6-chloro-9-(tetrahydropyran-2-yl)purine
6-chloro-9-tetrahydropyranyl-9H-purine
6-chloro-N9-(2-tetrahydropyranyl)-purine
6-chloro-9-(tetrahydro-2-pyranyl)purine
6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
6-chloro-9-(tetrahydro-pyran-2-yl)-9H-purine
6-chloro-9-(tetrahydropyran-2-yl)-9H-purine
6-chloro-9-(tetrahydropyran-2-yl)purine
6-chloro-9-tetrahydropyranyl-9H-purine
6-chloro-N9-(2-tetrahydropyranyl)-purine
Articles
Holy, Antonin;
Dvorakova, Hana;
Dvorak, Dalimil, Coupling of 6-chloropurines with organocuprates derived from Grignard reagents: A convenient route to sec and tert 6-alkylpurines. Tetrahedron Letters 1996, 37(8), 1285 - 1288, 10.1016/0040-4039(95)02375-5 
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Holy, Antonin;
Dvorakova, Hana;
Dvorak, Dalimil, Synthesis of acyclic nucleotide analogues derived from 6-(sec-OR tert-alkyl)purines via coupling of 6-chloropurine derivatives with organocuprates. Collect. Czech. Chem. Commun. 1998, 63(12), 2065 - 2074.
Dvorak, Dalimil;
Havelkova, Martina;
Hocek, Michal;
Cesnek, Michal, The Suzuki-Miyaura cross-coupling reactions of 6-halopurines with boronic acids leading to 6-aryl- and 6-alkenylpurines. Synlett 1999(7), 1145 - 1147.
Holy, Antonin;
Hocek, Michal, A FACILE SYNTHESIS OF 6-CYANOPURINE BASES. Collect. Czech. Chem. Commun. 1995, 60(8), 1386 - 1389, 10.1135/cccc19951386 .
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Holy, Antonin;
Hocek, Michal;
Masojidkova, Milena, Synthesis of acyclic nucleotide analogues derived from N-substituted 6-(1-aminoethyl)purines via 6-acetylpurine derivatives. Tetrahedron 1997, 53(6), 2291 - 2302, 10.1016/S0040-4020(96)01130-1 .
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Holy, Antonin;
Dvorakova, Hana;
Hocek, Michal;
Votruba, Ivan, Synthesis and cytostatic activity of substituted 6-phenylpurine bases and nucleosides: Application of the Suzuki-Miyaura cross-coupling reactions of 6-chloropurine derivatives with phenylboronic acids. Journal of Medicinal Chemistry 2000, 43(9), 1817 - 1825, 10.1021/jm991167+ .
.
Holy, Antonin;
Dvorakova, Hana;
Hocek, Michal;
Votruba, Ivan, Cytostatic 6-arylpurine nucleosides II. Synthesis of sugar-modified derivatives: 9-(2-deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-deoxy-β-D-ribofuranosyl)- and 9-(2,3-dihydroxypropyl)-6-phenylpurines. Collect. Czech. Chem. Commun. 2000, 65(11), 1683 - 1697.
Dvorakova, Hana;
Stary, Ivo;
Hocek, Michal;
Stara, Irena G., Covalent analogues of DNA base-pairs and triplets IV. Synthesis of trisubstituted benzenes bearing purine and/or pyrimidine rings by cyclotrimerization of 6-ethynylpurines and/or 5-ethynyl-1,3-dimethyluracil. Collect. Czech. Chem. Commun. 2002, 67(8), 1223 - 1235, 10.1135/cccc20021223 .
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Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Silhar, Peter, Facile and efficient synthesis of 6-(hydroxymethyl)purines. Organic Letters 2004, 6(19), 3225 - 3228, 10.1021/ol049059r .
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Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Silhar, Peter, Synthesis of 2-substituted 6-(hydroxymethyl)purine bases and nucleosides. Collect. Czech. Chem. Commun. 2005, 70(10), 1669 - 1695, 10.1135/cccc20051669 .
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Hocek, Michal;
Silhar, Peter;
Hasnik, Zbynek, Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent. Tetrahedron Letters 2007, 48(32), 5589 - 5592, 10.1016/j.tetlet.2007.06.053 .
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Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Klepetarova, Blanka;
Kuchar, Martin, Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations. Organic and Biomolecular Chemistry 2008, 6(13), 2377 - 2387, 10.1039/b802833h .
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Kotora, Martin;
Hocek, Michal;
Turek, Pavel;
Pohl, Radek;
Klepetarova, Blanka, Cobalt-induced synthesis of 6-(pyridin-2-yl)purines by microwave-enhanced [2+2+2] cyclotrimerization. European Journal of Organic Chemistry 2008(19), 3335 - 3343, 10.1002/ejoc.200800205 .
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Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Hasnik, Zbynek, Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)-and 6-(carbamoylmethyl)purines. Collect. Czech. Chem. Commun. 2009, 74(7-8), 1035 - 1059, 10.1135/cccc2009042 .
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Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena, 6-Guanidinopurine nucleosides and their analogues. Tetrahedron 2002, 58(15), 2985 - 2996, 10.1016/S0040-4020(02)00186-2 .
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