Detail of compound @ czechem

Molecular Formula: C₁₂H₉ClN₄

Molecular weight: 244.67966

InChi: InChI=1S/C12H9ClN4/c13-11-10-12(15-7-14-11)17(8-16-10)6-9-4-2-1-3-5-9/h1-5,7-8H,6H2

InChi Key: NKEFCVAMNJICJZ-UHFFFAOYSA-N

SMILES: c12n(Cc3ccccc3)cnc1c(ncn2)Cl

Chemical Name
6-chloro-9-(phenylmethyl)-9H-purine
6-chloro-9-benzyl-9H-purine
6-chloro-9-benzylpurine
6-chloro-9-phenylmethyl-9H-purine
9-benzyl-6-chloro-9H-purine
9-Bn-6-chloropurine
N9-benzyl-6-chloropurine

External Links
PubChem

Authors of compound

Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Kotora, Martin
Jansa, Petr
Dvorak, Dalimil
Stary, Ivo
Havelkova, Martina
Hocek, Michal
Cesnek, Michal
Studenovsky, Martin
Tobrman, Tomas
Kotek, Vladislav
Chudikova, Nadezda
Votruba, Ivan
Koukal, Petr
Hockova, Dana
Stara, Irena G.
Turek, Pavel
Seckarova, Pavlina
Marek, Radek
Malinakova, Katerina
Kolehmainen, Erkki
Sklenar, Vladimir
Capek, Petr
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Kuchar, Martin
Hasnik, Zbynek
CAPEK Petr
Janeba, Zlatko
Sala, Michal
Cechova, Lucie

Articles

Dvorak, Dalimil; Havelkova, Martina; Hocek, Michal; Cesnek, Michal, The Suzuki-Miyaura cross-coupling reactions of 6-halopurines with boronic acids leading to 6-aryl- and 6-alkenylpurines. Synlett 1999(7), 1145 - 1147.

Dvorak, Dalimil; Havelkova, Martina; Studenovsky, Martin, N-substituted hypoxanthine derivatives from the reaction of 6-halopurines with Michael acceptors under the conditions of Heck reaction. Collect. Czech. Chem. Commun. 2000, 65(5), 797 - 804.

Dvorak, Dalimil; Havelkova, Martina; Hocek, Michal, Covalent analogues of DNA base-pairs and triplets. Part 3: Synthesis of 1,4- and 1,3-bis(purin-6-yl)benzenes and 1-(1,3-dimethyluracil-5-yl)-3 or 4-(purin-9-yl)benzenes. Tetrahedron 2002, 58(37), 7431 - 7435, 10.1016/S0040-4020(02)00833-5

Dvorak, Dalimil; Tobrman, Tomas, 'Reductive Heck reaction' of 6-halopurines. Tetrahedron Letters 2004, 45(2), 273 - 276, 10.1016/j.tetlet.2003.10.181

Dvorak, Dalimil; Tobrman, Tomas, Reductive dimerization of 2- and 6-iodopurines: Side reaction in Pd-catalyzed cross-coupling of iodopurines. Collect. Czech. Chem. Commun. 2007, 72(10), 1365 - 1374, 10.1135/cccc20071365

Dvorak, Dalimil; Tobrman, Tomas; Kotek, Vladislav; Chudikova, Nadezda, Selective synthesis of 7-substituted purines via 7,8-dihydropurines. Organic Letters 2010, 12(24), 5724 - 5727, 10.1021/ol1025525

Dvorakova, Hana; Dvorak, Dalimil; Tobrman, Tomas; Koukal, Petr, Palladium-catalysed Claisen rearrangement of 6-allyloxypurines. Chem. Pap. 2013, 67(1), 3 - 8,6, 10.2478/s11696-012-0239-y

Dvorak, Dalimil; Tobrman, Tomas, Regioselective and facile synthesis of 7,9-dialkyl-8-oxopurines from 7,9-dialkyl-7,8-dihydropurines: Total synthesis of heteromines i and J. Synthesis 2014, 46(5), 660 - 668, 10.1055/s-0033-1340499

Dvorakova, Hana; Stary, Ivo; Hocek, Michal; Stara, Irena G., Covalent analogues of DNA base-pairs and triplets IV. Synthesis of trisubstituted benzenes bearing purine and/or pyrimidine rings by cyclotrimerization of 6-ethynylpurines and/or 5-ethynyl-1,3-dimethyluracil. Collect. Czech. Chem. Commun. 2002, 67(8), 1223 - 1235, 10.1135/cccc20021223

Hocek, Michal; Hockova, Dana; Seckarova, Pavlina; Marek, Radek; Malinakova, Katerina; Kolehmainen, Erkki; Sklenar, Vladimir, Direct determination of tautomerism in purine derivatives by low-temperature NMR spectroscopy. Tetrahedron Letters 2004, 45(33), 6259 - 6263, 10.1016/j.tetlet.2004.06.088

Hocek, Michal; Capek, Petr; Pohl, Radek, Synthesis of enantiomerically pure (purin-6-yl)phenylalanines and their nucleosides, a novel type of purine-amino acid conjugates. Journal of Organic Chemistry 2005, 70(20), 8001 - 8008, 10.1021/jo051110x

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Silhar, Peter, Facile and efficient synthesis of 6-(hydroxymethyl)purines. Organic Letters 2004, 6(19), 3225 - 3228, 10.1021/ol049059r

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Silhar, Peter, Synthesis of 2-substituted 6-(hydroxymethyl)purine bases and nucleosides. Collect. Czech. Chem. Commun. 2005, 70(10), 1669 - 1695, 10.1135/cccc20051669

Hocek, Michal; Silhar, Peter; Hasnik, Zbynek, Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent. Tetrahedron Letters 2007, 48(32), 5589 - 5592, 10.1016/j.tetlet.2007.06.053

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Klepetarova, Blanka; Kuchar, Martin, Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations. Organic and Biomolecular Chemistry 2008, 6(13), 2377 - 2387, 10.1039/b802833h

Kotora, Martin; Hocek, Michal; Turek, Pavel; Pohl, Radek; Klepetarova, Blanka, Cobalt-induced synthesis of 6-(pyridin-2-yl)purines by microwave-enhanced [2+2+2] cyclotrimerization. European Journal of Organic Chemistry 2008(19), 3335 - 3343, 10.1002/ejoc.200800205

Hocek, Michal; Pohl, Radek; Hasnik, Zbynek, Cross-coupling reactions of halopurines with aryl- and alkyltrifluoroborates; the scope and limitations in the synthesis of modified purines. Synthesis 2009(8), 1309 - 1317, 10.1055/s-0028-1088038

Hocek, Michal; Pohl, Radek; Klepetarova, Blanka; Hasnik, Zbynek, Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)-and 6-(carbamoylmethyl)purines. Collect. Czech. Chem. Commun. 2009, 74(7-8), 1035 - 1059, 10.1135/cccc2009042

Holy, Antonin; Dracinsky, Martin; Jansa, Petr; Janeba, Zlatko; Sala, Michal; Cechova, Lucie, The optimized microwave-assisted decomposition of formamides and its synthetic utility in the amination reactions of purines. Tetrahedron 2011, 67(5), 866 - 871, 10.1016/j.tet.2010.12.040

Patents

Hocek, Michal; CAPEK Petr, (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF, WO2004/94426, 2004.