Molecular Formula: C12H9IN4
Molecular weight: 336.13113
InChi: InChI=1S/C12H9IN4/c13-11-10-12(15-7-14-11)17(8-16-10)6-9-4-2-1-3-5-9/h1-5,7-8H,6H2
InChi Key: QRWQLCUEMMKASG-UHFFFAOYSA-N
SMILES: c12n(Cc3ccccc3)cnc1c(ncn2)I
Chemical Name
6-iodo-9-benzylpurine
9-benzyl-6-iodo-9H-purine
9-Benzyl-6-iodopurine
6-iodo-9-benzylpurine
9-benzyl-6-iodo-9H-purine
9-Benzyl-6-iodopurine
Authors of compound
Cisarova, Ivana
Dvorakova, Hana
Kotora, Martin
Dvorak, Dalimil
Havelkova, Martina
Hocek, Michal
Cesnek, Michal
Studenovsky, Martin
Stepnicka, Petr
Tobrman, Tomas
Klecka, Martin
Kotek, Vladislav
Chudikova, Nadezda
Krovacek, Martin
Votruba, Ivan
Capek, Petr
Pohl, Radek
Silhar, Peter
Hasnik, Zbynek
Bambuch, Vitezslav
CAPEK Petr
Parkan, Kamil
Dvorakova, Hana
Kotora, Martin
Dvorak, Dalimil
Havelkova, Martina
Hocek, Michal
Cesnek, Michal
Studenovsky, Martin
Stepnicka, Petr
Tobrman, Tomas
Klecka, Martin
Kotek, Vladislav
Chudikova, Nadezda
Krovacek, Martin
Votruba, Ivan
Capek, Petr
Pohl, Radek
Silhar, Peter
Hasnik, Zbynek
Bambuch, Vitezslav
CAPEK Petr
Parkan, Kamil
Articles
Dvorak, Dalimil;
Havelkova, Martina;
Hocek, Michal;
Cesnek, Michal, The Suzuki-Miyaura cross-coupling reactions of 6-halopurines with boronic acids leading to 6-aryl- and 6-alkenylpurines. Synlett 1999(7), 1145 - 1147.
Dvorak, Dalimil;
Havelkova, Martina;
Studenovsky, Martin, N-substituted hypoxanthine derivatives from the reaction of 6-halopurines with Michael acceptors under the conditions of Heck reaction. Collect. Czech. Chem. Commun. 2000, 65(5), 797 - 804.
Dvorak, Dalimil;
Tobrman, Tomas, 'Reductive Heck reaction' of 6-halopurines. Tetrahedron Letters 2004, 45(2), 273 - 276, 10.1016/j.tetlet.2003.10.181 
.
.
Dvorak, Dalimil;
Tobrman, Tomas, 6-Magnesiated Purines: Preparation and Reaction with Aldehydes. Organic Letters 2003, 5(23), 4289 -, 10.1021/ol0355027 .
.
Dvorak, Dalimil;
Tobrman, Tomas;
Klecka, Martin, Cu(I)-catalyzed coupling of (9-benzylpurin-6-yl)magnesium chloride with allyl halides: An approach to 6-allylpurine derivatives. Collect. Czech. Chem. Commun. 2006, 71(8), 1221 - 1228, 10.1135/cccc20061221 .
.
Dvorak, Dalimil;
Tobrman, Tomas, Reductive dimerization of 2- and 6-iodopurines: Side reaction in Pd-catalyzed cross-coupling of iodopurines. Collect. Czech. Chem. Commun. 2007, 72(10), 1365 - 1374, 10.1135/cccc20071365 .
.
Cisarova, Ivana;
Dvorak, Dalimil;
Stepnicka, Petr;
Tobrman, Tomas, Preparation and crystal structures of purine 2,2′-, 6,6′-, and 8,8′-dimers. European Journal of Organic Chemistry 2008(12), 2167 - 2174, 10.1002/ejoc.200800017 .
.
Dvorak, Dalimil;
Tobrman, Tomas, Heck reactions of 6- and 2-halopurines. European Journal of Organic Chemistry 2008(17), 2923 - 2928, 10.1002/ejoc.200800091 .
.
Dvorak, Dalimil;
Tobrman, Tomas;
Kotek, Vladislav;
Chudikova, Nadezda, Selective synthesis of 7-substituted purines via 7,8-dihydropurines. Organic Letters 2010, 12(24), 5724 - 5727, 10.1021/ol1025525 .
.
Cisarova, Ivana;
Dvorakova, Hana;
Dvorak, Dalimil;
Krovacek, Martin;
Votruba, Ivan, 6-alkynylpurines bearing electronacceptor substituents: Preparation, reactivity in cycloaddition reactions and cytostatic activity. Collect. Czech. Chem. Commun. 2011, 76(12), 1487 - 1507, 10.1135/cccc2011176 .
.
Dvorak, Dalimil;
Tobrman, Tomas, Regioselective and facile synthesis of 7,9-dialkyl-8-oxopurines from 7,9-dialkyl-7,8-dihydropurines: Total synthesis of heteromines i and J. Synthesis 2014, 46(5), 660 - 668, 10.1055/s-0033-1340499 .
.
Hocek, Michal;
Votruba, Ivan, Covalent analogues of DNA base-pairs and triplets. Part 2: Synthesis and cytostatic activity of bis(purin-6-yl)acetylenes, -diacetylenes and related compounds. Bioorganic and Medicinal Chemistry Letters 2002, 12(7), 1055 - 1058, 10.1016/S0960-894X(02)00077-X .
.
Cisarova, Ivana;
Dvorakova, Hana;
Hocek, Michal, Covalent analogues of DNA base-pairs and triplets V. Synthesis of purine-purine and purine-pyrimidine conjugates connected by diverse types of acyclic carbon linkages. Collect. Czech. Chem. Commun. 2002, 67(10), 1560 - 1578, 10.1135/cccc20021560 .
.
Hocek, Michal, Synthesis of protected (purin-6-yl)glycines via Pd-catalyzed α-arylation of ethyl N-(diphenylmethylidene) glycinate with 6-iodopurines. Heterocycles 2004, 63(7), 1673 - 1677.
Hocek, Michal;
Capek, Petr;
Pohl, Radek, A facile and efficient synthesis of (purin-6-yl)alanines. Journal of Organic Chemistry 2004, 69(23), 7985 - 7988, 10.1021/jo048812r .
.
Hocek, Michal;
Capek, Petr;
Pohl, Radek, Synthesis of enantiomerically pure (purin-6-yl)phenylalanines and their nucleosides, a novel type of purine-amino acid conjugates. Journal of Organic Chemistry 2005, 70(20), 8001 - 8008, 10.1021/jo051110x .
.
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Silhar, Peter, Facile and efficient synthesis of 6-(hydroxymethyl)purines. Organic Letters 2004, 6(19), 3225 - 3228, 10.1021/ol049059r .
.
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Silhar, Peter, Synthesis of 2-substituted 6-(hydroxymethyl)purine bases and nucleosides. Collect. Czech. Chem. Commun. 2005, 70(10), 1669 - 1695, 10.1135/cccc20051669 .
.
Hocek, Michal;
Pohl, Radek;
Bambuch, Vitezslav, Synthesis of 6-(4,5-dihydrofuran-2-yl)- and 6-(tetrahydrofuran-2-yl)purine bases and nucleosides. European Journal of Organic Chemistry 2008(16), 2783 - 2788, 10.1002/ejoc.200800174 .
.
Hocek, Michal;
Pohl, Radek;
Hasnik, Zbynek, Synthesis of (purin-6-yl)methylphosphonate bases and nucleosides. Tetrahedron Letters 2010, 51(18), 2464 - 2466, 10.1016/j.tetlet.2010.02.167 .
.
Patents
Hocek, Michal;
CAPEK Petr, (PURIN-6-YL) AMINO ACID AND PRODUCTION METHOD THEREOF, WO2004/94426, 2004.