Detail of compound @ czechem

Molecular Formula: C₅H₈O

Molecular weight: 84.11642

InChi: InChI=1S/C5H8O/c1-2-4-6-5-3-1/h2,4H,1,3,5H2

InChi Key: BUDQDWGNQVEFAC-UHFFFAOYSA-N

SMILES: O1CCCC=C1

Chemical Name
2,3-dihydro-4H-pyran
2H-3,4-dihydropyran
3,4-dihydro-(2H)-pyran
3,4-dihydro-2H-pyran
3,4-dihydro-α-pyran
5,6-dihydro-4H-pyran

External Links
PubChem

Authors of compound

Budesinsky, Milos
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Menova, Petra
Kotora, Martin
Hocek, Michal
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
Otmar, Miroslav
Slavetinska, Lenka
Raindlova, Veronika
Perlikova, Pavla
Slavtinska, Lenka
Jornet Martinez, Neus
Bahador, Gina
Eberlin, Ludovic
Tloustova, Eva
Lee, Yu-Jen
Rosenberg, Ivan
Hrebabecky, Hubert
Jurikova, Kristina
Smrckova, Svatava
Janeba, Zlatko
Meszarosova, Katerina
Tichy, Tomas
Antonin, Holy
Jan Marie Rene, Balzarini
Hana, Dvorakova
Erik Desire Alice, De Clercq
Pour, Milan
Eignerova, Barbara
Bartunek, Petr
Negishi, Ei-Ichi
Cederbaum, Frederik E.
Sedlak, David
Kralikova, Sarka

Articles

Holy, Antonin; Hocek, Michal, A FACILE SYNTHESIS OF 6-CYANOPURINE BASES. Collect. Czech. Chem. Commun. 1995, 60(8), 1386 - 1389, 10.1135/cccc19951386

Holy, Antonin; Hocek, Michal, Perfluoroalkylation of 6-iodopurines by trimethyl(perfluoroalkyl)silanes. Synthesis of 6-(perfluoroalkyl)purine bases, nucleosides and acyclic nucleotide analogues. Collect. Czech. Chem. Commun. 1999, 64(2), 229 - 241.

Hocek, Michal; Perlikova, Pavla; Slavtinska, Lenka; Jornet Martinez, Neus, Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy- 2′,2′-difluororibonucleosides derived from 6-(het)aryl-7- deazapurines. Tetrahedron 2012, 68(39), 8300 - 8310, 10.1016/j.tet.2012.07.033

Menova, Petra; Hocek, Michal; Slavetinska, Lenka; Raindlova, Veronika; Perlikova, Pavla; Bahador, Gina; Eberlin, Ludovic; Tloustova, Eva; Lee, Yu-Jen, Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines. ChemMedChem 2013, 8(5), 832 - 846, 10.1002/cmdc.201300047

Krecmerova, Marcela; Holy, Antonin; Hrebabecky, Hubert, SYNTHESIS OF 5'-O-PHOSPHONOMETHYL DERIVATIVES OF PYRIMIDINE 2'-DEOXYNUCLEOSIDES. Collect. Czech. Chem. Commun. 1990, 55(10), 2521 - 2536.

Holy, Antonin, PREPARATION AND SYNTHETIC UTILIZATION OF 3-(ADENIN-9-YL)-2-HYDROXYALKANOIC ACIDS AND THEIR DERIVATIVES. Collect. Czech. Chem. Commun. 1984, 49(9), 2148 - 2166.

Holy, Antonin, SYNTHESIS OF 3-AMINO- AND 3-AZIDOANALOGS OF 9-(3-HYDROXY-2-PHOSPHONYLMETHOXYPROPYL)ADENINE (HPMPA). Collect. Czech. Chem. Commun. 1989, 54(2), 446 - 454.

Krecmerova, Marcela; Holy, Antonin; Masojidkova, Milena; Hrebabecky, Hubert, PREPARATION OF PURINE 2'-DEOXY-5'-O-PHOSPHONOMETHYLNUCLEOSIDES AND 2'-DEOXY-3'-O-PHOSPHONOMETHYLNUCLEOSIDES. Collect. Czech. Chem. Commun. 1993, 58(2), 421 - 434, 10.1135/cccc19930421

Holy, Antonin; Masojidkova, Milena; Otmar, Miroslav; Rosenberg, Ivan, <5-(ADENIN-9-YL)-5-DEOXYPENTOFURANOSYL>PHOSPHONATES - A NOVEL TYPE NUCLEOTIDE ANALOGS RELATED TO HPMPA. I. DERIVATIVES WITH L-arabino, D-arabino, 2-DEOXY-L-erythro AND 2-DEOXY-L-threo CONFIGURATION. Collect. Czech. Chem. Commun. 1993, 58(9), 2159 - 2179, 10.1135/cccc19932159

Holy, Antonin; Masojidkova, Milena; Otmar, Miroslav; Rosenberg, Ivan, <5-(ADENIN-9-YL)-5-DEOXY-L-PENTOFURANOSYL>PHOSPHONATES - A NOVEL TYPE OF NUCLEOTIDE ANALOGS RELATED TO HPMPA. II. SYNTHESIS OF L-ribo and L-xylo CONFIGURATED DERIVATIVES BY RECYCLIZATION OF DIETHYL (5-RS)-<1,2-O-ISOPROPYLIDENE-5-O-METHANESULFONYL-D-PENTOFURANOS-5-C-YL>PHOSPHONATES .... Collect. Czech. Chem. Commun. 1993, 58(9), 2180 - 2196, 10.1135/cccc19932180

Holy, Antonin; Jurikova, Kristina; Smrckova, Svatava, SYNTHESIS OF BASE-MODIFIED "ABBREVIATED" NAD ANALOGUES. Collect. Czech. Chem. Commun. 1995, 60(2), 237 - 250, 10.1135/cccc19950237

Holy, Antonin; Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. I. THE STEPWISE APPROACH. Collect. Czech. Chem. Commun. 1995, 60(7), 1196 - 1212, 10.1135/cccc19951196

Holy, Antonin; Masojidkova, Milena; Meszarosova, Katerina, Synthesis of acyclic adenine 8,N-anhydronucleosides. Collect. Czech. Chem. Commun. 2000, 65(7), 1109 - 1125.

Holy, Antonin; Masojidkova, Milena; Janeba, Zlatko, Alternative synthesis of 9-{3-[(diisopropoxyphosphoryl)-methoxy]-2- hydroxypropyl}adenine and its free phosphonates substituted at the c-8 position of purine base. Collect. Czech. Chem. Commun. 2010, 75(3), 371 - 381, 10.1135/cccc2009569

Krecmerova, Marcela; Holy, Antonin; Dracinsky, Martin; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; Tichy, Tomas, New prodrugs of Adefovir and Cidofovir. Bioorganic and Medicinal Chemistry 2011, 19(11), 3527 - 3539, 10.1016/j.bmc.2011.04.016

Kotora, Martin; Pour, Milan; Negishi, Ei-Ichi; Cederbaum, Frederik E., Strictly regio- and stereo-controlled α-alkenylation of bicyclic enone derivatives via palladium-catalyzed cross coupling and its application to a formal synthesis of (±)-carbacyclin. Tetrahedron 1998, 54(25), 7057 - 7074, 10.1016/S0040-4020(98)00347-0

Dracinsky, Martin; Kotora, Martin; Eignerova, Barbara; Bartunek, Petr; Sedlak, David, Synthesis and biochemical characterization of a series of 17α-perfluoroalkylated estradiols as selective ligands for estrogen receptor α. Journal of Medicinal Chemistry 2010, 53(19), 6947 - 6953, 10.1021/jm100563h

Budesinsky, Milos; Masojidkova, Milena; Rosenberg, Ivan; Kralikova, Sarka, Study on reactivity and protection of the α-hydroxyphosphonate moiety in 5′-nucleotide analogues: Formation of the 3′-O-P-C(OH)-C4′ internucleotide linkage. Nucleosides, Nucleotides and Nucleic Acids 2003, 22(3), 329 - 347, 10.1081/NCN-120021432

Patents

Antonin, Holy; Jan Marie Rene, Balzarini; Hana, Dvorakova; Erik Desire Alice, De Clercq, Antiretroviral enantiomeric nucleotide analogs, US6653296, 2003.