Detail of compound @ czechem

Molecular Formula: C₁₂H₁₂N₄O

Molecular weight: 228.24988

InChi: InChI=1S/C12H12N4O/c1-2-9-11-12(14-7-13-9)16(8-15-11)10-5-3-4-6-17-10/h1,7-8,10H,3-6H2

InChi Key: REXLPPQBTQFZPG-UHFFFAOYSA-N

SMILES: c12n(C3OCCCC3)cnc1c(ncn2)C#C

Chemical Name
6-ethynyl-9-(tetrahydropyran-2-yl)purine

External Links
PubChem

Authors of compound

Cisarova, Ivana
Tislerova, Iva
Dvorakova, Hana
Kotora, Martin
Stary, Ivo
Hocek, Michal
Votruba, Ivan
Stara, Irena G.
Turek, Pavel
Pohl, Radek
Kuchar, Martin

Articles

Dvorakova, Hana; Stary, Ivo; Hocek, Michal; Stara, Irena G., Cyclotrimerization of 6-ethynylpurines. Synthesis of 1,2,4- and 1,3,5-tris(purin-6-yl)benzenes as novel Hoogsteen-triplet analogues. Tetrahedron Letters 2001, 42(3), 519 - 521.

Hocek, Michal; Votruba, Ivan, Covalent analogues of DNA base-pairs and triplets. Part 2: Synthesis and cytostatic activity of bis(purin-6-yl)acetylenes, -diacetylenes and related compounds. Bioorganic and Medicinal Chemistry Letters 2002, 12(7), 1055 - 1058, 10.1016/S0960-894X(02)00077-X

Dvorakova, Hana; Stary, Ivo; Hocek, Michal; Stara, Irena G., Covalent analogues of DNA base-pairs and triplets IV. Synthesis of trisubstituted benzenes bearing purine and/or pyrimidine rings by cyclotrimerization of 6-ethynylpurines and/or 5-ethynyl-1,3-dimethyluracil. Collect. Czech. Chem. Commun. 2002, 67(8), 1223 - 1235, 10.1135/cccc20021223

Cisarova, Ivana; Dvorakova, Hana; Hocek, Michal, Covalent analogues of DNA base-pairs and triplets V. Synthesis of purine-purine and purine-pyrimidine conjugates connected by diverse types of acyclic carbon linkages. Collect. Czech. Chem. Commun. 2002, 67(10), 1560 - 1578, 10.1135/cccc20021560

Cisarova, Ivana; Tislerova, Iva; Kotora, Martin; Hocek, Michal; Votruba, Ivan; Turek, Pavel, Cocyclotrimerization of 6-alkynylpurines with α,ω-diynes as a novel approach to biologically active 6-arylpurines. Journal of Organic Chemistry 2004, 69(26), 9224 - 9233, 10.1021/jo0486342

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Kuchar, Martin, Synthesis of purines bearing functionalized C-substituents by the conjugate addition of nucleophiles to 6-vinylpurines and 6-ethynylpurines. European Journal of Organic Chemistry 2006(22), 5083 - 5098, 10.1002/ejoc.200600545