Molecular Formula: C3H9BrSi
Molecular weight: 153.09306
InChi: InChI=1S/C3H9BrSi/c1-5(2,3)4/h1-3H3
InChi Key: IYYIVELXUANFED-UHFFFAOYSA-N
SMILES: [Si](Br)(C)(C)C
Chemical Name
bromo trimethyl silane
bromotrimethyl silane
bromotrimethylsilane
trimethyl silyl bromide
trimethylbromosilane
trimethylsilyl bromide
trimethylsilylbromide
bromo trimethyl silane
bromotrimethyl silane
bromotrimethylsilane
trimethyl silyl bromide
trimethylbromosilane
trimethylsilyl bromide
trimethylsilylbromide
Authors of compound
Cisarova, Ivana
Budesinsky, Milos
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Petricek, Vaclav
Hocek, Michal
Cesnek, Michal
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Pohl, Radek
Mackman, Richard
Slavetinska, Lenka
Cihlar, Tomas
Bahador, Gina
Tloustova, Eva
Rosenberg, Ivan
Liboska, Radek
Sigel, Helmut
Guenter, Jaroslav
Janeba, Zlatko
Zidek, Zdenek
Tocik, Zdenek
Gomez-Coca, Raquel B.
Kapinos, Larisa E.
Vilaplana, Rosario A.
Gonzalez-Vilchez, Francisco
Naesens, Lieve
Slouf, Miroslav
Pomeisl, Karel
Vrbovska, Silvie
Neyts, Johan
Vrbkova, Silvie
Kasicka, Vaclav
Keough, Dianne T.
De Jersey, John
Guddat, Luke W.
Tichy, Tomas
Brehova, Petra
Laflamme, Genevieve
Hui, Hon
Baszczynski, Ondrej
Stepan, George
Sazelova, Petra
Rejman, Dominik
Antonin, Holy
Jan Marie Rene, Balzarini
Hana, Dvorakova
Erik Desire Alice, De Clercq
Jan M. R., Balzarini
Erik D. A., De Clercq
Spacek, Petr
Wang, Tzu-Hsuan
Auwerx, Joeri
Kiss, Eleonora
Goris, Nesya
Edstein, Michael D.
Chavchich, Marina
Kralikova, Sarka
Pav, Ondrej
Dvorakova, Ivana
Barvik, Ivan
Kosiova, Ivana
Simak, Ondrej
Panova, Natalya
Petrova, Magdalena
Budesinsky, Milos
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Petricek, Vaclav
Hocek, Michal
Cesnek, Michal
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Pohl, Radek
Mackman, Richard
Slavetinska, Lenka
Cihlar, Tomas
Bahador, Gina
Tloustova, Eva
Rosenberg, Ivan
Liboska, Radek
Sigel, Helmut
Guenter, Jaroslav
Janeba, Zlatko
Zidek, Zdenek
Tocik, Zdenek
Gomez-Coca, Raquel B.
Kapinos, Larisa E.
Vilaplana, Rosario A.
Gonzalez-Vilchez, Francisco
Naesens, Lieve
Slouf, Miroslav
Pomeisl, Karel
Vrbovska, Silvie
Neyts, Johan
Vrbkova, Silvie
Kasicka, Vaclav
Keough, Dianne T.
De Jersey, John
Guddat, Luke W.
Tichy, Tomas
Brehova, Petra
Laflamme, Genevieve
Hui, Hon
Baszczynski, Ondrej
Stepan, George
Sazelova, Petra
Rejman, Dominik
Antonin, Holy
Jan Marie Rene, Balzarini
Hana, Dvorakova
Erik Desire Alice, De Clercq
Jan M. R., Balzarini
Erik D. A., De Clercq
Spacek, Petr
Wang, Tzu-Hsuan
Auwerx, Joeri
Kiss, Eleonora
Goris, Nesya
Edstein, Michael D.
Chavchich, Marina
Kralikova, Sarka
Pav, Ondrej
Dvorakova, Ivana
Barvik, Ivan
Kosiova, Ivana
Simak, Ondrej
Panova, Natalya
Petrova, Magdalena
Articles
Holy, Antonin;
Hocek, Michal;
Cesnek, Michal, Synthesis of acyclic nucleotide analogues derived from 2-amino-6-C-substituted purines via cross-coupling reactions of 2-amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with diverse organometallic reagents. Collect. Czech. Chem. Commun. 2000, 65(8), 1357 - 1373.
Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Guenter, Jaroslav, Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base. Journal of Medicinal Chemistry 1999, 42(12), 2064 - 2086, 10.1021/jm9811256 
.
.
Holy, Antonin;
Sigel, Helmut;
Gomez-Coca, Raquel B.;
Kapinos, Larisa E.;
Vilaplana, Rosario A.;
Gonzalez-Vilchez, Francisco, Metal ion-binding properties of 9-(4-phosphonobutyl)adenine (dPMEA), a sister compound of the antiviral nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA), and quantification of the equilibria involving four Cu(PMEA) isomers. Journal of the Chemical Society, Dalton Transactions 2000(13), 2077 - 2084, 10.1039/b001588l .
.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Tloustova, Eva, Synthesis and cytostatic activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N-substituted adenines, 2,6-diaminopurines and related compounds. Collect. Czech. Chem. Commun. 2001, 66(10), 1545 - 1592.
Cisarova, Ivana;
Holy, Antonin;
Petricek, Vaclav;
Slouf, Miroslav, Charge density study of hydrogen [(2,4-diaminopyrimidin-1-io)methyl]phosphonate monohydrate. Acta Crystallographica Section B: Structural Science 2002, 58(3 PART 2), 519 - 529, 10.1107/S0108768102004020 .
.
Holy, Antonin;
Masojidkova, Milena;
Pohl, Radek;
Vrbovska, Silvie, Bifunctional acyclic nucleoside phosphonates. 1. Symmetrical 1,3-bis[(phosphonomethoxy)propan-2-yl] derivatives of purines and pyrimidines. Collect. Czech. Chem. Commun. 2006, 71(4), 543 - 566, 10.1135/cccc20060543 .
.
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Preparation of C-5 substituted cidofovir derivatives. Collect. Czech. Chem. Commun. 2006, 71(4), 579 - 594, 10.1135/cccc20060579 .
.
Holy, Antonin;
Votruba, Ivan;
Pohl, Radek;
Pomeisl, Karel, Syntheses of base and side-chain modified pyrimidine 1-[2- (phosphonomethoxy)propyl] derivatives as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma. Collect. Czech. Chem. Commun. 2006, 71(4), 595 - 624, 10.1135/cccc20060595 .
.
Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Cihlar, Tomas;
Naesens, Lieve;
Pomeisl, Karel;
Neyts, Johan;
Tichy, Tomas;
Brehova, Petra;
Laflamme, Genevieve;
Hui, Hon, Synthesis of ester prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] -2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. Journal of Medicinal Chemistry 2010, 53(19), 6825 - 6837, 10.1021/jm901828c .
.
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Mackman, Richard;
Cihlar, Tomas;
Bahador, Gina;
Janeba, Zlatko;
Zidek, Zdenek;
Baszczynski, Ondrej;
Stepan, George, A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities. European Journal of Medicinal Chemistry 2011, 46(9), 3748 - 3754, 10.1016/j.ejmech.2011.05.040 .
.
Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
Guddat, Luke W.;
Baszczynski, Ondrej, The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. European Journal of Medicinal Chemistry 2013, 67, 81 - 89, 10.1016/j.ejmech.2013.06.032 .
.
Krecmerova, Marcela;
Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Neyts, Johan;
Kasicka, Vaclav;
Stepan, George;
Sazelova, Petra;
Auwerx, Joeri;
Kiss, Eleonora;
Goris, Nesya, 9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: Optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro. Bioorganic and Medicinal Chemistry 2013, 21(5), 1199 - 1208, 10.1016/j.bmc.2012.12.044 .
.
Hockova, Dana;
Slavetinska, Lenka;
Janeba, Zlatko;
Naesens, Lieve;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Tichy, Tomas;
Spacek, Petr;
Wang, Tzu-Hsuan;
Edstein, Michael D.;
Chavchich, Marina, Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. Journal of Medicinal Chemistry 2013, 56(6), 2513 - 2526, 10.1021/jm301893b .
.
Krecmerova, Marcela;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Pohl, Radek, N-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: Chemistry and antiviral activity. Bioorganic and Medicinal Chemistry 2014, 22(10), 2896 - 2906, 10.1016/j.bmc.2014.03.031 .
.
Budesinsky, Milos;
Masojidkova, Milena;
Rosenberg, Ivan;
Liboska, Radek;
Tocik, Zdenek;
Dvorakova, Ivana, Electrophile-promoted addition of hydroxymethylphosphonate to 4′,5′-didehydronucleosides: a way to novel isosteric analogues of 5′-nucleotides. Tetrahedron 2007, 63(21), 4516 - 4534, 10.1016/j.tet.2007.03.059 .
.
Budesinsky, Milos;
Masojidkova, Milena;
Rosenberg, Ivan;
Tocik, Zdenek;
Kralikova, Sarka;
Barvik, Ivan, Synthesis and properties of ApA analogues with shortened phosphonate internucleotide linkage. Nucleosides, Nucleotides and Nucleic Acids 2011, 30(7-8), 524 - 543, 10.1080/15257770.2011.581259 .
.
Budesinsky, Milos;
Rosenberg, Ivan;
Liboska, Radek;
Rejman, Dominik;
Pav, Ondrej;
Kosiova, Ivana;
Simak, Ondrej;
Panova, Natalya;
Petrova, Magdalena, Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres. European Journal of Medicinal Chemistry 2014, 74, 145 - 168, 10.1016/j.ejmech.2013.12.026 .
.