Molecular Formula: C3H9Al
Molecular weight: 72.085098
InChi: InChI=1S/3CH3.Al/h3*1H3;
InChi Key: JLTRXTDYQLMHGR-UHFFFAOYSA-N
SMILES: [Al](C)(C)C
Chemical Name
Al(CH3)3
Al(methyl)3
trimethyl-aluminium
trimethyl-aluminum
trimethylaluminium
trimethylaluminum
tris(methyl)aluminum
Al(CH3)3
Al(methyl)3
trimethyl-aluminium
trimethyl-aluminum
trimethylaluminium
trimethylaluminum
tris(methyl)aluminum
Authors of compound
Cisarova, Ivana
Naus, Petr
Holy, Antonin
Malkov, Andrei V.
Kocovsky, Pavel
Dvorakova, Hana
Hodacova, Jana
Eigner, Vaclav
Necas, David
Kotora, Martin
Hocek, Michal
Cesnek, Michal
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Stambasky, Jan
Capek, Petr
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Urban, Milan
Cerna, Igor
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Vrabel, Milan
Hasnik, Zbynek
Joubert, Nicolas
Barta, Jan
Ernsting, Nikolaus P.
Otmar, Miroslav
Bambuch, Vitezslav
Stefko, Martin
Slavetinska, Lenka
Dzubak, Petr
Hajduch, Marian
Kubelka, Tomas
Perlikova, Pavla
Konecny, Petr
Kubelka, Toma
Slavtinska, Lenka
Chapuis, Hubert
Bahador, Gina
Tichy, Michal
Lee, Yu-Jen
Tloust'Ova, Eva
Weber, Jan
Caletkova, Olga
Bogdanova, Katerina
Kolar, Milan
Vrbkova, Jana
Kadlcikova, Aneta
Valterova, Irena
Westwater, Mary-Margaret
Gutnov, Andrey
Ramirez-Lopez, Pedro
Friscourt, Frederic
Rankovic, Zoran
Guenter, Jaroslav
Janeba, Zlatko
Brehova, Petra
Sedlacek, Ondrej
Valasek, Michal
Michl, Josef
Stursa, Jan
Kaleta, Jiri
Akdag, Akin
Tarabek, Jan
Svatos, Ales
Hovorka, Oldrich
Urbanova, Klara
Naus, Petr
Holy, Antonin
Malkov, Andrei V.
Kocovsky, Pavel
Dvorakova, Hana
Hodacova, Jana
Eigner, Vaclav
Necas, David
Kotora, Martin
Hocek, Michal
Cesnek, Michal
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Stambasky, Jan
Capek, Petr
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Urban, Milan
Cerna, Igor
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Vrabel, Milan
Hasnik, Zbynek
Joubert, Nicolas
Barta, Jan
Ernsting, Nikolaus P.
Otmar, Miroslav
Bambuch, Vitezslav
Stefko, Martin
Slavetinska, Lenka
Dzubak, Petr
Hajduch, Marian
Kubelka, Tomas
Perlikova, Pavla
Konecny, Petr
Kubelka, Toma
Slavtinska, Lenka
Chapuis, Hubert
Bahador, Gina
Tichy, Michal
Lee, Yu-Jen
Tloust'Ova, Eva
Weber, Jan
Caletkova, Olga
Bogdanova, Katerina
Kolar, Milan
Vrbkova, Jana
Kadlcikova, Aneta
Valterova, Irena
Westwater, Mary-Margaret
Gutnov, Andrey
Ramirez-Lopez, Pedro
Friscourt, Frederic
Rankovic, Zoran
Guenter, Jaroslav
Janeba, Zlatko
Brehova, Petra
Sedlacek, Ondrej
Valasek, Michal
Michl, Josef
Stursa, Jan
Kaleta, Jiri
Akdag, Akin
Tarabek, Jan
Svatos, Ales
Hovorka, Oldrich
Urbanova, Klara
Articles
Holy, Antonin;
Hocek, Michal;
Cesnek, Michal, Synthesis of acyclic nucleotide analogues derived from 2-amino-6-C-substituted purines via cross-coupling reactions of 2-amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with diverse organometallic reagents. Collect. Czech. Chem. Commun. 2000, 65(8), 1357 - 1373.
Holy, Antonin;
Dvorakova, Hana;
Hocek, Michal, Cytostatic 6-arylpurine nucleosides IV. Synthesis of 2-substituted 6-phenylpurine ribonucleosides. Collect. Czech. Chem. Commun. 2002, 67(3), 325 - 335, 10.1135/cccc20020325 
.
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Hocek, Michal;
Hockova, Dana;
Stambasky, Jan, Cytostatic 6-arylpurine nucleosides V. synthesis of 8-substituted 6-phenylpurine ribonucleosides. Collect. Czech. Chem. Commun. 2003, 68(5), 837 - 848, 10.1135/cccc20030837 .
.
Dvorakova, Hana;
Hocek, Michal, An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed cross-coupling reactions of 2,6-dichloropurines. Journal of Organic Chemistry 2003, 68(14), 5773 - 5776, 10.1021/jo034351i .
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Hocek, Michal;
Pohl, Radek, Regioselectivity in cross-coupling reactions of 2,6,8-trichloro-9- (tetrahydropyran-2-yl)purine: Synthesis of 2,6,8-trisubstituted purine bases. Synthesis 2004(17), 2869 - 2876, 10.1055/s-2004-834881 .
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Cisarova, Ivana;
Hocek, Michal;
Pohl, Radek, Highly methylated purines and purinium salts as analogues of heteromines. European Journal of Organic Chemistry 2005(14), 3026 - 3030, 10.1002/ejoc.200500154 .
.
Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Urban, Milan, New modular and efficient approach to 6-substituted pyridin-2-yl C-nucleosides. Journal of Organic Chemistry 2006, 71(19), 7322 - 7328, 10.1021/jo061080d .
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Hocek, Michal;
Silhar, Peter;
Shih, I-hung;
Mabery, Eric;
Mackman, Richard, Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine l-ribonucleosides. Bioorganic and Medicinal Chemistry Letters 2006, 16(20), 5290 - 5293, 10.1016/j.bmcl.2006.07.092 .
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Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Klepetarova, Blanka;
Silhar, Peter, Synthesis of 6-amino-, 6-methyl- and 6-aryl-2-(hydroxymethyl)purine bases and nucleosides. Collect. Czech. Chem. Commun. 2006, 71(6), 788 - 803, 10.1135/cccc20060788 .
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Hocek, Michal;
Capek, Petr;
Pohl, Radek;
Vrabel, Milan;
Hasnik, Zbynek, Aqueous-phase Suzuki-Miyaura cross-coupling reactions of free halopurine bases. Synthesis 2006(20), 3515 - 3526, 10.1055/s-2006-950240 .
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Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Joubert, Nicolas, Modular and practical synthesis of 6-substituted pyridin-3-yl C-nucleosides. Journal of Organic Chemistry 2007, 72(18), 6797 - 6805, 10.1021/jo0709504 .
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Hocek, Michal;
Pohl, Radek;
Silhar, Peter, Cytostatic and antiviral 6-arylpurine ribonucleosides VIII. Synthesis and evaluation of 6-substituted purine 3′-deoxyribonucleosides. Collect. Czech. Chem. Commun. 2006, 71(10), 1484 - 1496, 10.1135/cccc20061484 .
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Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Barta, Jan;
Ernsting, Nikolaus P., Modular synthesis of 5-substituted thiophen-2-yl C-2′- deoxyribonucleosides. Journal of Organic Chemistry 2008, 73(10), 3798 - 3806, 10.1021/jo800177y .
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Naus, Petr;
Hocek, Michal;
Kuchar, Martin, Cytostatic and antiviral 6-arylpurine ribonucleosides IX. Synthesis and evaluation of 6-substituted 3-deazapurine ribonucleosides. Collect. Czech. Chem. Commun. 2008, 73(5), 665 - 678, 10.1135/cccc20080665 .
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Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Stefko, Martin, A modular methodology for the synthesis of 4- and 3-substituted benzene and aniline C-ribonucleosides. European Journal of Organic Chemistry 2008(10), 1689 - 1704, 10.1002/ejoc.200701168 .
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Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Cerna, Igor, Synthesis of 6,8,9-tri- and 2,6,8,9-tetrasubstituted purines by a combination of the Suzuki cross-coupling, N-arylation, and direct C-H arylation reactions. Journal of Organic Chemistry 2008, 73(22), 9048 - 9054, 10.1021/jo8018126 .
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Hocek, Michal;
Klepetarova, Blanka;
Stefko, Martin;
Slavetinska, Lenka, A general and efficient synthesis of pyridin-2-yl C-ribonucleosides bearing diverse alkyl, aryl, amino, and carbamoyl groups in position 6. Journal of Organic Chemistry 2010, 75(2), 442 - 449, 10.1021/jo902313g .
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Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Cerna, Igor, Intramolecular direct C-H arylation approach to fused purines. Synthesis of purino[8, 9-f]phenanthridines and 5, 6-dihydropurino[8, 9-a]isoquinolines. Journal of Organic Chemistry 2010, 75(7), 2302 - 2308, 10.1021/jo100111t .
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Hocek, Michal;
Kubelka, Toma;
Slavtinska, Lenka, A general regioselective approach to 2,4-disubstituted pyrimidin-5-yl C-2-deoxyribonucleosides. Synthesis 2012, 44(6), 953 - 965, 10.1055/s-0031-1289694 .
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Hocek, Michal;
Pohl, Radek;
Joubert, Nicolas;
Kubelka, Tomas;
Chapuis, Hubert, Synthesis of 6-substituted 2(1H)-pyridon-3-yl C-2′- deoxyribonucleosides. European Journal of Organic Chemistry 2012(9), 1759 - 1767, 10.1002/ejoc.201101662 .
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Naus, Petr;
Hocek, Michal;
Pohl, Radek;
Perlikova, Pavla, Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-c-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides. Collect. Czech. Chem. Commun. 2011, 76(8), 957 - 988, 10.1135/cccc2011082 .
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Hocek, Michal;
Slavetinska, Lenka;
Kubelka, Tomas, Synthesis of substituted benzyl homo-C-ribonucleosides and -nucleotides as carba analogues of phosphoribosylanthranilate. European Journal of Organic Chemistry 2012(26), 4969 - 4981, 10.1002/ejoc.201200819 .
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Eigner, Vaclav;
Hocek, Michal;
Slavetinska, Lenka;
Kubelka, Tomas, Synthesis of 2,6-disubstituted pyridin-3-yl C-2′-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides. Organic and Biomolecular Chemistry 2013, 11(28), 4702 - 4718, 10.1039/c3ob40774h .
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Hocek, Michal;
Pohl, Radek;
Bahador, Gina;
Tichy, Michal;
Lee, Yu-Jen;
Tloust'Ova, Eva;
Weber, Jan, Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic and Medicinal Chemistry 2013, 21(17), 5362 - 5372, 10.1016/j.bmc.2013.06.011 .
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Naus, Petr;
Hocek, Michal;
Slavetinska, Lenka;
Dzubak, Petr;
Hajduch, Marian;
Perlikova, Pavla;
Konecny, Petr;
Tloust'Ova, Eva;
Caletkova, Olga;
Bogdanova, Katerina;
Kolar, Milan;
Vrbkova, Jana, Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides. Journal of Medicinal Chemistry 2014, 57(3), 1097 - 1110, 10.1021/jm4018948 .
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Malkov, Andrei V.;
Kocovsky, Pavel;
Hodacova, Jana;
Kotora, Martin;
Kadlcikova, Aneta;
Westwater, Mary-Margaret;
Gutnov, Andrey;
Ramirez-Lopez, Pedro;
Friscourt, Frederic;
Rankovic, Zoran, New pyridine N-oxides as chiral organocatalysts in the asymmetric allylation of aromatic aldehydes. Tetrahedron 2008, 64(49), 11335 - 11348, 10.1016/j.tet.2008.08.084 .
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Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Guenter, Jaroslav, Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base. Journal of Medicinal Chemistry 1999, 42(12), 2064 - 2086, 10.1021/jm9811256 .
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Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana, 5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy) ethoxy]pyrimidines-Acyclic Nucleoside Phosphonate Analogues with Antiviral Activity. Journal of Medicinal Chemistry 2003, 46(23), 5064 - 5073.
Holy, Antonin;
Masojidkova, Milena;
Pohl, Radek;
Otmar, Miroslav;
Bambuch, Vitezslav, C-Functionalization of 9-deazapurines by cross-coupling reactions. Tetrahedron 2007, 63(7), 1589 - 1601, 10.1016/j.tet.2006.12.008 .
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Holy, Antonin;
Pohl, Radek;
Janeba, Zlatko;
Brehova, Petra;
Sedlacek, Ondrej, The synthesis of the 8-C-substituted 2,6-diamino-9-[2-(phosphonomethoxy) ethyl]purine (PMEDAP) derivatives by diverse cross-coupling reactions. Canadian Journal of Chemistry 2011, 89(4), 488 - 498, 10.1139/V11-001 .
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Cisarova, Ivana;
Necas, David;
Kotora, Martin, Iron-catalyzed transformations of 2-chloro-1,6-heptadienes. European Journal of Organic Chemistry 2004(6), 1280 - 1285, 10.1002/ejoc.200300660 .
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Necas, David;
Kotora, Martin, Ring opening of methylenecycloalkenes via the C-C bond cleavage. Organic Letters 2008, 10(22), 5261 - 5263, 10.1021/ol801728f .
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Pohl, Radek;
Valasek, Michal;
Michl, Josef;
Stursa, Jan, Lithium salts of [1,12-Dialkyl-CBMe] anions. Inorganic Chemistry 2010, 49(22), 10255 - 10263, 10.1021/ic101235e .
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Pohl, Radek;
Michl, Josef;
Kaleta, Jiri;
Akdag, Akin;
Tarabek, Jan, The 16 CB(CH)(CD) radicals with 5-fold substitution symmetry: Spin density distribution in CBMe. Inorganic Chemistry 2012, 51(20), 10819 - 10824,6, 10.1021/ic301236s .
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