Molecular Formula: C4H5BO2S
Molecular weight: 127.9573
InChi: InChI=1S/C4H5BO2S/c6-5(7)4-1-2-8-3-4/h1-3,6-7H
InChi Key: QNMBSXGYAQZCTN-UHFFFAOYSA-N
SMILES: c1(B(O)O)cscc1
Chemical Name
3-thiophen boronic acid
3-thiopheneboronic acid
3-thiophenylboronic acid
thiophen-3-yl boronic acid
Thiophene-3-boronic acid
thiophene-3-yl boronic acid
3-thiophen boronic acid
3-thiopheneboronic acid
3-thiophenylboronic acid
thiophen-3-yl boronic acid
Thiophene-3-boronic acid
thiophene-3-yl boronic acid
Authors of compound
Naus, Petr
Holy, Antonin
Menova, Petra
Hocek, Michal
Votruba, Ivan
Capek, Petr
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Furman, Phillip A.
Tharnish, Phillip M.
Otto, Michael J.
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Vrabel, Milan
Hasnik, Zbynek
Barta, Jan
Ernsting, Nikolaus P.
Slavetinska, Lenka
Dzubak, Petr
Hajduch, Marian
Ameral, Ria
Birkus, Gabriel
Wang, Ting
Ray, Adrian S.
Cihlar, Tomas
Raindlova, Veronika
Spacilova, Pavla
Snasel, Jan
Zabranska, Helena
Pichova, Iva
Perlikova, Pavla
Shih, Robert
Bourderioux, Aurelie
Konecny, Petr
Stray, Kirsten M.
Feng, Joy Y.
Slavtinska, Lenka
Jornet Martinez, Neus
Bahador, Gina
Tichy, Michal
Xu, Hao Ying
Chen, Yen-Liang
Yokokawa, Fumiaki
Shi, Pei-Yong
Eberlin, Ludovic
Tloustova, Eva
Lee, Yu-Jen
Tloust'Ova, Eva
Weber, Jan
Caletkova, Olga
Bogdanova, Katerina
Kolar, Milan
Vrbkova, Jana
Horska, Kvetoslava
Janeba, Zlatko
Pomeisl, Karel
Brehova, Petra
Sedlacek, Ondrej
Holy, Antonin
Menova, Petra
Hocek, Michal
Votruba, Ivan
Capek, Petr
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Furman, Phillip A.
Tharnish, Phillip M.
Otto, Michael J.
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Vrabel, Milan
Hasnik, Zbynek
Barta, Jan
Ernsting, Nikolaus P.
Slavetinska, Lenka
Dzubak, Petr
Hajduch, Marian
Ameral, Ria
Birkus, Gabriel
Wang, Ting
Ray, Adrian S.
Cihlar, Tomas
Raindlova, Veronika
Spacilova, Pavla
Snasel, Jan
Zabranska, Helena
Pichova, Iva
Perlikova, Pavla
Shih, Robert
Bourderioux, Aurelie
Konecny, Petr
Stray, Kirsten M.
Feng, Joy Y.
Slavtinska, Lenka
Jornet Martinez, Neus
Bahador, Gina
Tichy, Michal
Xu, Hao Ying
Chen, Yen-Liang
Yokokawa, Fumiaki
Shi, Pei-Yong
Eberlin, Ludovic
Tloustova, Eva
Lee, Yu-Jen
Tloust'Ova, Eva
Weber, Jan
Caletkova, Olga
Bogdanova, Katerina
Kolar, Milan
Vrbkova, Jana
Horska, Kvetoslava
Janeba, Zlatko
Pomeisl, Karel
Brehova, Petra
Sedlacek, Ondrej
Articles
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Furman, Phillip A.;
Tharnish, Phillip M.;
Otto, Michael J., Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides. Journal of Medicinal Chemistry 2005, 48(18), 5869 - 5873, 10.1021/jm050335x 
.
.
Hocek, Michal;
Silhar, Peter;
Shih, I-hung;
Mabery, Eric;
Mackman, Richard, Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine l-ribonucleosides. Bioorganic and Medicinal Chemistry Letters 2006, 16(20), 5290 - 5293, 10.1016/j.bmcl.2006.07.092 .
.
Hocek, Michal;
Capek, Petr;
Pohl, Radek;
Vrabel, Milan;
Hasnik, Zbynek, Aqueous-phase Suzuki-Miyaura cross-coupling reactions of free halopurine bases. Synthesis 2006(20), 3515 - 3526, 10.1055/s-2006-950240 .
.
Hocek, Michal;
Pohl, Radek;
Silhar, Peter, Cytostatic and antiviral 6-arylpurine ribonucleosides VIII. Synthesis and evaluation of 6-substituted purine 3′-deoxyribonucleosides. Collect. Czech. Chem. Commun. 2006, 71(10), 1484 - 1496, 10.1135/cccc20061484 .
.
Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Barta, Jan;
Ernsting, Nikolaus P., Modular synthesis of 5-substituted thiophen-2-yl C-2′- deoxyribonucleosides. Journal of Organic Chemistry 2008, 73(10), 3798 - 3806, 10.1021/jo800177y .
.
Naus, Petr;
Hocek, Michal;
Kuchar, Martin, Cytostatic and antiviral 6-arylpurine ribonucleosides IX. Synthesis and evaluation of 6-substituted 3-deazapurine ribonucleosides. Collect. Czech. Chem. Commun. 2008, 73(5), 665 - 678, 10.1135/cccc20080665 .
.
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Mackman, Richard;
Dzubak, Petr;
Hajduch, Marian;
Ameral, Ria;
Birkus, Gabriel;
Wang, Ting;
Ray, Adrian S.;
Cihlar, Tomas, 6-(Het)aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents. Journal of Medicinal Chemistry 2010, 53(1), 460 - 470, 10.1021/jm901428k .
.
Hocek, Michal;
Klepetarova, Blanka;
Barta, Jan;
Slavetinska, Lenka, Modular synthesis of 5-substituted furan-2-yl C-2'-deoxyribonudeosides and biaryl covalent base-pair analogues. European Journal of Organic Chemistry 2010(28), 5432 - 5443, 10.1002/ejoc.201000726 .
.
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Ameral, Ria;
Birkus, Gabriel;
Cihlar, Tomas;
Spacilova, Pavla;
Snasel, Jan;
Zabranska, Helena;
Pichova, Iva, CycloSal-phosphate pronucleotides of cytostatic 6-(het)aryl-7-deazapurine ribonucleosides: Synthesis, cytostatic activity, and inhibition of adenosine kinases. ChemMedChem 2010, 5(8), 1386 - 1396, 10.1002/cmdc.201000192 .
.
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Birkus, Gabriel;
Cihlar, Tomas;
Perlikova, Pavla;
Shih, Robert, Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides. Bioorganic and Medicinal Chemistry 2011, 19(1), 229 - 242, 10.1016/j.bmc.2010.11.029 .
.
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Dzubak, Petr;
Hajduch, Marian;
Birkus, Gabriel;
Wang, Ting;
Ray, Adrian S.;
Cihlar, Tomas;
Pichova, Iva;
Perlikova, Pavla;
Bourderioux, Aurelie;
Konecny, Petr;
Stray, Kirsten M.;
Feng, Joy Y., Synthesis and significant cytostatic activity of 7-hetaryl-7- deazaadenosines. Journal of Medicinal Chemistry 2011, 54(15), 5498 - 5507, 10.1021/jm2005173 .
.
Naus, Petr;
Hocek, Michal;
Pohl, Radek;
Perlikova, Pavla, Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-c-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides. Collect. Czech. Chem. Commun. 2011, 76(8), 957 - 988, 10.1135/cccc2011082 .
.
Hocek, Michal;
Perlikova, Pavla;
Slavtinska, Lenka;
Jornet Martinez, Neus, Synthesis of 2′-deoxy-2′-fluororibo- and 2′-deoxy- 2′,2′-difluororibonucleosides derived from 6-(het)aryl-7- deazapurines. Tetrahedron 2012, 68(39), 8300 - 8310, 10.1016/j.tet.2012.07.033 .
.
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Slavetinska, Lenka;
Birkus, Gabriel;
Cihlar, Tomas;
Perlikova, Pavla;
Bourderioux, Aurelie;
Bahador, Gina, Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′- fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic and Medicinal Chemistry 2012, 20(17), 5202 - 5214, 10.1016/j.bmc.2012.07.003 .
.
Hocek, Michal;
Pohl, Radek;
Tichy, Michal;
Xu, Hao Ying;
Chen, Yen-Liang;
Yokokawa, Fumiaki;
Shi, Pei-Yong, Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic and Medicinal Chemistry 2012, 20(20), 6123 - 6133,11, 10.1016/j.bmc.2012.08.021 .
.
Menova, Petra;
Hocek, Michal;
Slavetinska, Lenka;
Raindlova, Veronika;
Perlikova, Pavla;
Bahador, Gina;
Eberlin, Ludovic;
Tloustova, Eva;
Lee, Yu-Jen, Synthesis and Cytostatic and Antiviral Activities of 2′-Deoxy-2′,2′-difluororibo- and 2′-Deoxy-2′-fluororibonucleosides Derived from 7-(Het)aryl-7-deazaadenines. ChemMedChem 2013, 8(5), 832 - 846, 10.1002/cmdc.201300047 .
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Hocek, Michal;
Pohl, Radek;
Bahador, Gina;
Tichy, Michal;
Lee, Yu-Jen;
Tloust'Ova, Eva;
Weber, Jan, Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic and Medicinal Chemistry 2013, 21(17), 5362 - 5372, 10.1016/j.bmc.2013.06.011 .
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Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Dzubak, Petr;
Hajduch, Marian;
Snasel, Jan;
Pichova, Iva;
Perlikova, Pavla;
Konecny, Petr, 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. MedChemComm 2013, 4(11), 1497 - 1500, 10.1039/c3md00232b .
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Naus, Petr;
Hocek, Michal;
Slavetinska, Lenka;
Dzubak, Petr;
Hajduch, Marian;
Perlikova, Pavla;
Konecny, Petr;
Tloust'Ova, Eva;
Caletkova, Olga;
Bogdanova, Katerina;
Kolar, Milan;
Vrbkova, Jana, Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides. Journal of Medicinal Chemistry 2014, 57(3), 1097 - 1110, 10.1021/jm4018948 .
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Holy, Antonin;
Pohl, Radek;
Horska, Kvetoslava;
Pomeisl, Karel, Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylase. Tetrahedron 2009, 65(41), 8486 - 8492, 10.1016/j.tet.2009.08.039 .
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