Detail of compound @ czechem

Molecular Formula: C₆H₁₅ClSi

Molecular weight: 150.7218

InChi: InChI=1S/C6H15ClSi/c1-6(2,3)8(4,5)7/h1-5H3

InChi Key: BCNZYOJHNLTNEZ-UHFFFAOYSA-N

SMILES: [Si](C(C)(C)C)(Cl)(C)C

Chemical Name
(1,1-dimethylethyl)dimethylsilyl chloride
2-(chlorodimethylsilyl)-2-methylpropane
chloro(1,1-dimethylethyl)dimethylsilane
dimethyl-(1,1-dimethylethyl)chlorosilane
dimethyl-(1,1-dimethylethyl)silyl chloride
tert-butyl-dimethyl-silyl chloride
tert-butyldimethylsilyl chloride

External Links
PubChem

Authors of compound

Naus, Petr
Tislerova, Iva
Hrdina, Radim
Trnka, Tomas
Budesinsky, Milos
Holy, Antonin
Dracinsky, Martin
Malkov, Andrei V.
Kocovsky, Pavel
Svoboda, Jiri
Eigner, Vaclav
Cejka, Jan
Necas, David
Kotora, Martin
Tursky, Matyas
Hocek, Michal
Votruba, Ivan
Masojidkova, Milena
Stambasky, Jan
Pohl, Radek
Klepetarova, Blanka
Urban, Milan
Joubert, Nicolas
Barta, Jan
Ernsting, Nikolaus P.
Stefko, Martin
Slavetinska, Lenka
Dzubak, Petr
Hajduch, Marian
Birkus, Gabriel
Wang, Ting
Ray, Adrian S.
Cihlar, Tomas
Kubelka, Tomas
Snasel, Jan
Pichova, Iva
Perlikova, Pavla
Bourderioux, Aurelie
Konecny, Petr
Stray, Kirsten M.
Feng, Joy Y.
Kapras, Votech
Kysilka, Ondrej
Kubelka, Toma
Slavtinska, Lenka
Chapuis, Hubert
Valterova, Irena
Rosenberg, Ivan
Liboska, Radek
Janeba, Zlatko
Pomeisl, Karel
Vrbkova, Silvie
Rejman, Dominik
Guenee, Laure
Vishe, Mahesh
Besnard, Celine
Lacour, Jerome
Pour, Milan
Robins, Morris J.
Lin, Xiaoyu
Vesely, Jan
Michl, Josef
Eignerova, Barbara
Negishi, Ei-Ichi
Cederbaum, Frederik E.
Korotvicka, Ales
Hessler, Filip
Prchalova, Eva
Motloch, Petr
Valterov, Irena
Parkan, Kamil
Paleta, Oldrich
Kvicala, Jaroslav
Machara, Ales
Magnera, Thomas F.
Schoeberl, Ulrich
Harrison, Robin M.
Fleischer, Frank
Pflug, Jodi L.
Schwab, Peter F. H.
Meng, Xiangsheng
Lipiak, Dariusz
Noll, Bruce C.
Allured, Viloya S.
Rudalevige, Trevor
Lee, Stephen
Kralikova, Sarka
Barvik, Ivan
Simak, Ondrej
Pav, Ondej
Toik, Zdenek
Novak, Pavel
Zelenka, Karel
Drasar, Pavel
Monti, Donato
Cinti, Stefano
Naitana, Mario Luigi
Schiaffino, Luca
Venanzi, Mariano
Laguzzi, Giuseppe
Luvidi, Loredana
Mancini, Giovanna
Novakova, Zdena
Wimmer, Zdenek
Rydner, Lina
Oscarson, Stefan

Articles

Hocek, Michal; Pohl, Radek; Klepetarova, Blanka; Urban, Milan, New modular and efficient approach to 6-substituted pyridin-2-yl C-nucleosides. Journal of Organic Chemistry 2006, 71(19), 7322 - 7328, 10.1021/jo061080d

Hocek, Michal; Pohl, Radek; Klepetarova, Blanka; Joubert, Nicolas, Modular and practical synthesis of 6-substituted pyridin-3-yl C-nucleosides. Journal of Organic Chemistry 2007, 72(18), 6797 - 6805, 10.1021/jo0709504

Hocek, Michal; Pohl, Radek; Klepetarova, Blanka; Barta, Jan; Ernsting, Nikolaus P., Modular synthesis of 5-substituted thiophen-2-yl C-2′- deoxyribonucleosides. Journal of Organic Chemistry 2008, 73(10), 3798 - 3806, 10.1021/jo800177y

Hocek, Michal; Pohl, Radek; Urban, Milan; Joubert, Nicolas, Modular Synthesis of 4-aryl- and 4-amino-substituted benzene C-2′-Deoxyribonucleosides. Synthesis 2008(12), 1918 - 1932, 10.1055/s-2008-1067038

Hocek, Michal; Klepetarova, Blanka; Slavetinska, Lenka; Kubelka, Tomas, Synthesis of 2,4-disubstituted pyrimidin-5-yl C-2′- deoxyribonucleosides by sequential regioselective reactions of 2,4-dichloropyrimidine nucleosides. European Journal of Organic Chemistry 2010(14), 2666 - 2669, 10.1002/ejoc.201000164

Naus, Petr; Hocek, Michal; Votruba, Ivan; Pohl, Radek; Dzubak, Petr; Hajduch, Marian; Birkus, Gabriel; Wang, Ting; Ray, Adrian S.; Cihlar, Tomas; Pichova, Iva; Perlikova, Pavla; Bourderioux, Aurelie; Konecny, Petr; Stray, Kirsten M.; Feng, Joy Y., Synthesis and significant cytostatic activity of 7-hetaryl-7- deazaadenosines. Journal of Medicinal Chemistry 2011, 54(15), 5498 - 5507, 10.1021/jm2005173

Malkov, Andrei V.; Kocovsky, Pavel; Hocek, Michal; Stambasky, Jan; Stefko, Martin; Kapras, Votech; Kysilka, Ondrej, A modular approach to aryl-C-ribonucleosides via the allylic substitution and ring-closing metathesis sequence. A stereocontrolled synthesis of all four α-/β- and D-/L-C-nucleoside stereoisomers. Journal of Organic Chemistry 2011, 76(19), 7781 - 7803, 10.1021/jo201110z

Hocek, Michal; Kubelka, Toma; Slavtinska, Lenka, A general regioselective approach to 2,4-disubstituted pyrimidin-5-yl C-2-deoxyribonucleosides. Synthesis 2012, 44(6), 953 - 965, 10.1055/s-0031-1289694

Hocek, Michal; Pohl, Radek; Joubert, Nicolas; Kubelka, Tomas; Chapuis, Hubert, Synthesis of 6-substituted 2(1H)-pyridon-3-yl C-2′- deoxyribonucleosides. European Journal of Organic Chemistry 2012(9), 1759 - 1767, 10.1002/ejoc.201101662

Eigner, Vaclav; Hocek, Michal; Slavetinska, Lenka; Kubelka, Tomas, Synthesis of 2,6-disubstituted pyridin-3-yl C-2′-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides. Organic and Biomolecular Chemistry 2013, 11(28), 4702 - 4718, 10.1039/c3ob40774h

Holy, Antonin; Dracinsky, Martin; Vrbkova, Silvie, Bifunctional acyclic nucleoside phosphonates: synthesis of chiral 9-{3-hydroxy[1,4-bis(phosphonomethoxy)]butan-2-yl} derivatives of purines. Tetrahedron Asymmetry 2007, 18(18), 2233 - 2247, 10.1016/j.tetasy.2007.09.021

Hrdina, Radim; Guenee, Laure; Vishe, Mahesh; Besnard, Celine; Lacour, Jerome, One-pot multi-component synthesis and solid state structures of functionally rich polyether macrocycles. Advanced Synthesis and Catalysis 2013, 355(16), 3161 - 3169, 10.1002/adsc.201300462

Janeba, Zlatko; Robins, Morris J.; Lin, Xiaoyu, Functionalization of Guanosine and 2′-Deoxyguanosine at C6: A Modified Appel Process and SAr Displacement of Imidazole. Nucleosides, Nucleotides and Nucleic Acids 2004, 23(1-2), 137 - 147, 10.1081/NCN-120027823

Kotora, Martin; Negishi, Ei-Ichi, Efficient and diastereoselective synthesis of (+)-goniobutenolide A via palladium-catalyzed ene-yne cross coupling-lactonization cascade. Tetrahedron Letters 1996, 37(50), 9041 - 9042, 10.1016/S0040-4039(96)01972-7

Kotora, Martin; Pour, Milan; Negishi, Ei-Ichi; Cederbaum, Frederik E., Strictly regio- and stereo-controlled α-alkenylation of bicyclic enone derivatives via palladium-catalyzed cross coupling and its application to a formal synthesis of (±)-carbacyclin. Tetrahedron 1998, 54(25), 7057 - 7074, 10.1016/S0040-4020(98)00347-0

Tislerova, Iva; Necas, David; Kotora, Martin; Tursky, Matyas, Nickel-catalyzed cyclization of α,ω-dienes: Formation vs. cleavage of C-C bonds. New Journal of Chemistry 2006, 30(5), 671 - 674, 10.1039/b601631f

Dracinsky, Martin; Kotora, Martin; Eignerova, Barbara, Perfluoroalkylation through cross-metathesis between alkenes and (perfluoroalkyl)propenes. European Journal of Organic Chemistry 2008(26), 4493 - 4499, 10.1002/ejoc.200800230

Kotora, Martin; Votruba, Ivan; Prchalova, Eva, Sphingosine and clavaminol H derivatives bearing fluorinated chains and their cytotoxic activity. Journal of Fluorine Chemistry 2012, 141, 49 - 57, 10.1016/j.jfluchem.2012.06.005

Kotora, Martin; Motloch, Petr; Valterov, Irena, Enantioselective allylation of thiophene-2-carbaldehyde: Formal total synthesis of duloxetine. Advanced Synthesis and Catalysis 2014, 356(1), 199 - 204, 10.1002/adsc.201300849

Kotora, Martin; Pohl, Radek; Parkan, Kamil, Cross-coupling reaction of saccharide-based alkenyl boronic acids with aryl halides: The synthesis of bergenin. Chemistry - A European Journal 2014, 20(15), 4414 - 4419, 10.1002/chem.201304304

Necas, David; Kotora, Martin; Valterova, Irena; Korotvicka, Ales; Hessler, Filip, Syntheses of a flobufen metabolite and dapoxetine based on enantioselective allylation of aromatic aldehydes. European Journal of Organic Chemistry 2014, 2014(12), 2543 - 2548, 10.1002/ejoc.201301899

Cejka, Jan; Pomeisl, Karel; Paleta, Oldrich; Kvicala, Jaroslav, Synthesis of 3-fluorofuran-2(5H)-ones based on Z/E photoisomerisation and cyclisation of 2-fluoro-4-hydroxybut-2-enoates. European Journal of Organic Chemistry 2007(35), 5917 - 5925, 10.1002/ejoc.200700439

Pomeisl, Karel; Paleta, Oldrich; Kvicala, Jaroslav, Convenient synthesis of 3-fluoro-4,5-diphenylfuran-2(5H)-one from benzoin ethers. Novel and efficient Z-E isomerisation and cyclisation of 2-fluoroalkenoate precursors, substitution of vinylic fluorine. Journal of Fluorine Chemistry 2006, 127(10 SPEC. ISS.), 1390 - 1397, 10.1016/j.jfluchem.2006.05.012

Svoboda, Jiri; Machara, Ales, Thiophenium-ylides: Synthesis and reactivity. Chem. Pap. 2013, 67(1), 59 - 65,7, 10.2478/s11696-012-0222-7

Michl, Josef; Magnera, Thomas F.; Schoeberl, Ulrich; Harrison, Robin M.; Fleischer, Frank; Pflug, Jodi L.; Schwab, Peter F. H.; Meng, Xiangsheng; Lipiak, Dariusz; Noll, Bruce C.; Allured, Viloya S.; Rudalevige, Trevor; Lee, Stephen, Toward a hexagonal grid polymer: Synthesis, coupling, and chemically reversible surface-pinning of the star connectors, 1,3,5- CH(CBHCX). Journal of the American Chemical Society 1997, 119(17), 3907 - 3917, 10.1021/ja963331d

Budesinsky, Milos; Masojidkova, Milena; Rosenberg, Ivan; Kralikova, Sarka, Study on reactivity and protection of the α-hydroxyphosphonate moiety in 5′-nucleotide analogues: Formation of the 3′-O-P-C(OH)-C4′ internucleotide linkage. Nucleosides, Nucleotides and Nucleic Acids 2003, 22(3), 329 - 347, 10.1081/NCN-120021432

Budesinsky, Milos; Pohl, Radek; Snasel, Jan; Rosenberg, Ivan; Liboska, Radek; Rejman, Dominik; Barvik, Ivan; Pav, Ondej; Toik, Zdenek; Novak, Pavel, 4′-Alkoxy oligodeoxynucleotides: A novel class of RNA mimics. Organic and Biomolecular Chemistry 2011, 9(24), 8261 - 8267, 10.1039/c1ob06148h

Tislerova, Iva; Trnka, Tomas; Simak, Ondrej; Zelenka, Karel; Drasar, Pavel; Monti, Donato; Cinti, Stefano; Naitana, Mario Luigi; Schiaffino, Luca; Venanzi, Mariano; Laguzzi, Giuseppe; Luvidi, Loredana; Mancini, Giovanna; Novakova, Zdena; Wimmer, Zdenek, Spectroscopic, morphological, and mechanistic investigation of the solvent-promoted aggregation of porphyrins modified in meso-positions by glucosylated steroids. Chemistry - A European Journal 2011, 17(49), 13743 - 13753, 10.1002/chem.201101163

Vesely, Jan; Rydner, Lina; Oscarson, Stefan, Variant synthetic pathway to glucuronic acid-containing di- and trisaccharide thioglycoside building blocks for continued synthesis of Cryptococcus neoformans capsular polysaccharide structures. Carbohydr. Res. 2008, 343(12), 2200 - 2208, 10.1016/j.carres.2007.11.026

Patents

Naus, Petr; Hocek, Michal; Bourderioux, Aurelie, NOVEL 7-DEAZAPURINE NUCLEOSIDES FOR THERAPEUTIC USES, WO2010/121576, 2010.