Molecular Formula: C11H13IN4O3
Molecular weight: 376.15039
InChi: InChI=1S/C11H13IN4O3/c12-5-2-16(8-1-6(18)7(3-17)19-8)11-9(5)10(13)14-4-15-11/h2,4,6-8,17-18H,1,3H2,(H2,13,14,15)/t6-,7+,8+/m0/s1
InChi Key: LIIIRHQRQZIIRT-XLPZGREQSA-N
SMILES: c12n([C@@H]3O[C@@H]([C@H](C3)O)CO)cc(c1c(ncn2)N)I
Chemical Name
2'-deoxy-7-iodotubercidin
2′-deoxy-7-iodo-7-deazaadenosine
4-amino-7-(2'-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
4-amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine
7-deaza-2'-deoxy-7-iodoadenosine
7-I-7-deaza-dATP
2'-deoxy-7-iodotubercidin
2′-deoxy-7-iodo-7-deazaadenosine
4-amino-7-(2'-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
4-amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine
7-deaza-2'-deoxy-7-iodoadenosine
7-I-7-deaza-dATP
Authors of compound
Naus, Petr
Dadova, Jitka
Hocek, Michal
Votruba, Ivan
Capek, Petr
Pohl, Radek
Klepetarova, Blanka
Vrabel, Milan
Havran, Ludek
Fojta, Miroslav
Rulisek, Lubomir
Cahova, Hana
Gloeckner, Christian
Marx, Andreas
Ernsting, Nikolaus P.
Pivonkova, Hana
Sajadi, Mohsen
Kovalenko, Sergey A.
Bednarova, Lucie
Horakova, Petra
Kalachova, Lubica
Sebest, Peter
Riedl, Jan
Slavetinska, Lenka
Birkus, Gabriel
Cihlar, Tomas
Raindlova, Veronika
Ikonen, Satu
MacIkova-Cahova, Hana
Anda, Miloslav
Perlikova, Pavla
Macickova-Cahova, Hana
Spacek, Jan
Kielkowski, Pavel
Bourderioux, Aurelie
Balintova, Jana
Vidlakova, Pavlina
Bahador, Gina
Simkov, Eva
Fanfrlik, Jindrich
Plucnara, Medard
Simkova, Eva
Dadova, Jitka
Hocek, Michal
Votruba, Ivan
Capek, Petr
Pohl, Radek
Klepetarova, Blanka
Vrabel, Milan
Havran, Ludek
Fojta, Miroslav
Rulisek, Lubomir
Cahova, Hana
Gloeckner, Christian
Marx, Andreas
Ernsting, Nikolaus P.
Pivonkova, Hana
Sajadi, Mohsen
Kovalenko, Sergey A.
Bednarova, Lucie
Horakova, Petra
Kalachova, Lubica
Sebest, Peter
Riedl, Jan
Slavetinska, Lenka
Birkus, Gabriel
Cihlar, Tomas
Raindlova, Veronika
Ikonen, Satu
MacIkova-Cahova, Hana
Anda, Miloslav
Perlikova, Pavla
Macickova-Cahova, Hana
Spacek, Jan
Kielkowski, Pavel
Bourderioux, Aurelie
Balintova, Jana
Vidlakova, Pavlina
Bahador, Gina
Simkov, Eva
Fanfrlik, Jindrich
Plucnara, Medard
Simkova, Eva
Articles
Hocek, Michal;
Capek, Petr;
Pohl, Radek;
Cahova, Hana;
Gloeckner, Christian;
Marx, Andreas, An efficient method for the construction of functionalized dna bearing amino acid groups through cross-coupling reactions of nucleoside triphosphates followed by primer extension or PCR. Chemistry - A European Journal 2007, 13(21), 6196 - 6203, 10.1002/chem.200700220 .
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Vrabel, Milan;
Ernsting, Nikolaus P.;
Sajadi, Mohsen;
Kovalenko, Sergey A., Synthesis and photophysical properties of 7-deaza-2′-deoxyadenosines bearing bipyridine ligands and their Ru(ii)-complexes in position 7. Organic and Biomolecular Chemistry 2008, 6(16), 2852 - 2860, 10.1039/b805632c .
Hocek, Michal;
Pohl, Radek;
Havran, Ludek;
Fojta, Miroslav;
Horakova, Petra;
Sebest, Peter;
Riedl, Jan, Tetrathiafulvalene-labelled nucleosides and nucleoside triphosphates: Synthesis, electrochemistry and the scope of their polymerase incorporation into DNA. European Journal of Organic Chemistry 2009(21), 3519 - 3525, 10.1002/ejoc200900392 .
Hocek, Michal;
Pohl, Radek;
Ikonen, Satu;
MacIkova-Cahova, Hana;
Anda, Miloslav, Synthesis of nucleoside and nucleotide conjugates of bile acids, and polymerase construction of bile acid-functionalized DNA. Organic and Biomolecular Chemistry 2010, 8(5), 1194 - 1201, 10.1039/b924072a .
Hocek, Michal;
Pohl, Radek;
Havran, Ludek;
Fojta, Miroslav;
Horakova, Petra;
Macickova-Cahova, Hana;
Spacek, Jan, Alkylsulfanylphenyl derivatives of cytosine and 7-deazaadenine nucleosides, nucleotides and nucleoside triphosphates: Synthesis, polymerase incorporation to DNA and electrochemical study. Chemistry - A European Journal 2011, 17(21), 5833 - 5841, 10.1002/chem.201003496 .
Hocek, Michal;
Pohl, Radek;
Kielkowski, Pavel, Synthesis of acetylene linked double-nucleobase nucleos(t)ide building blocks and polymerase construction of DNA containing cytosines in the major groove. Journal of Organic Chemistry 2011, 76(9), 3457 - 3462, 10.1021/jo200436j .
Hocek, Michal;
Pohl, Radek;
Macickova-Cahova, Hana;
Kielkowski, Pavel, Transient and switchable (Triethylsilyl)ethynyl protection of DNA against cleavage by restriction endonucleases. Angewandte Chemie - International Edition 2011, 50(37), 8727 - 8730, 10.1002/anie.201102898 .
Hocek, Michal;
Pohl, Radek;
Havran, Ludek;
Fojta, Miroslav;
Horakova, Petra;
Balintova, Jana;
Vidlakova, Pavlina, Anthraquinone as a redox label for DNA: Synthesis, enzymatic incorporation, and electrochemistry of anthraquinone-modified nucleosides, nucleotides, and DNA. Chemistry - A European Journal 2011, 17(50), 14063 - 14073, 10.1002/chem.201101883 .
Hocek, Michal;
Pohl, Radek;
Rulisek, Lubomir;
Riedl, Jan, Synthesis and photophysical properties of biaryl-substituted nucleos(t)ides. Polymerase synthesis of DNA probes bearing solvatochromic and pH-sensitive dual fluorescent and F NMR labels. Journal of Organic Chemistry 2012, 77(2), 1026 - 1044, 10.1021/jo202321g .
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Slavetinska, Lenka;
Birkus, Gabriel;
Cihlar, Tomas;
Perlikova, Pavla;
Bourderioux, Aurelie;
Bahador, Gina, Sugar-modified derivatives of cytostatic 7-(het)aryl-7-deazaadenosines: 2′-C-methylribonucleosides, 2′-deoxy-2′- fluoroarabinonucleosides, arabinonucleosides and 2′-deoxyribonucleosides. Bioorganic and Medicinal Chemistry 2012, 20(17), 5202 - 5214, 10.1016/j.bmc.2012.07.003 .
Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Havran, Ludek;
Fojta, Miroslav;
Pivonkova, Hana;
Horakova, Petra;
Raindlova, Veronika;
Simkov, Eva, Synthesis of hydrazone-modified nucleotides and their polymerase incorporation onto DNA for redox labeling. ChemPlusChem 2012, 77(8), 652 - 662, 10.1002/cplu.201200056 .
Hocek, Michal;
Pohl, Radek;
Bednarova, Lucie;
Kalachova, Lubica;
Fanfrlik, Jindrich, Synthesis of nucleosides and dNTPs bearing oligopyridine ligands linked through an octadiyne tether, their incorporation into DNA and complexation with transition metal cations. Organic and Biomolecular Chemistry 2013, 11(1), 78 - 89, 10.1039/c2ob26881g .
Hocek, Michal;
Pohl, Radek;
Havran, Ludek;
Fojta, Miroslav;
Balintova, Jana;
Vidlakova, Pavlina;
Plucnara, Medard, Benzofurazane as a new redox label for electrochemical detection of DNA: Towards multipotential redox coding of DNA bases. Chemistry - A European Journal 2013, 19(38), 12720 - 12731, 10.1002/chem.201301868 .
Dadova, Jitka;
Hocek, Michal;
Pohl, Radek;
Havran, Ludek;
Fojta, Miroslav;
Vidlakova, Pavlina, Aqueous heck cross-coupling preparation of acrylate-modified nucleotides and nucleoside triphosphates for polymerase synthesis of acrylate-labeled DNA. Journal of Organic Chemistry 2013, 78(19), 9627 - 9637, 10.1021/jo4011574 .
Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Havran, Ludek;
Fojta, Miroslav;
Pivonkova, Hana;
Horakova, Petra;
Raindlova, Veronika;
Simkova, Eva, Synthesis of hydrazone-modified nucleotides and their polymerase incorporation onto DNA for redox labeling. Collection of Czechoslovak Chemical Communications 2012, 77(8), 652 - 662.