Molecular Formula: C3H7N
Molecular weight: 57.09438
InChi: InChI=1S/C3H7N/c4-3-1-2-3/h3H,1-2,4H2
InChi Key: HTJDQJBWANPRPF-UHFFFAOYSA-N
SMILES: C1(CC1)N
Chemical Name
anhydrous cyclopropylamine
c-propyl amine
cyclopropanamine
cyclopropyl-amine
cyclopropylamine
cyclopropylNH2
N-cyclopropylamine
anhydrous cyclopropylamine
c-propyl amine
cyclopropanamine
cyclopropyl-amine
cyclopropylamine
cyclopropylNH2
N-cyclopropylamine
Authors of compound
Budesinsky, Milos
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Jansa, Petr
Hocek, Michal
Cesnek, Michal
Votruba, Ivan
Krystof, Vladimir
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Shih, I-hung
Mabery, Eric
Mackman, Richard
Hasnik, Zbynek
Stefko, Martin
Tloustova, Eva
Tloust'Ova, Eva
Hrebabecky, Hubert
Clercq, Erik de
Horska, Kveta
Janeba, Zlatko
Meszarosova, Katerina
Naesens, Lieve
Sala, Michal
Dolakova, Petra
Nencka, Radim
Horejsi, Katerina
Chalupova, Sarka
Vrbovska, Silvie
Neyts, Johan
Vrbkova, Silvie
Solinova, Veronika
Kasicka, Vaclav
Dejmek, Milan
De Palma, Armando M.
Keough, Dianne T.
Guddat, Luke W.
Hebabecky, Hubert
Draeinsky, Martin
Cechova, Lucie
Baszczynski, Ondrej
Mertlikova-Kaiserova, Helena
Prochazkova, Eliska
Kolman, Viktor
Kostinova, Alexandra
Doleckova, Iva
Brynda, Jiri
Voller, Jiri
Luebbers, Thomas
Angehrn, Peter
Gmuender, Hans
Herzig, Silvia
Kulhanek, Josef
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Jansa, Petr
Hocek, Michal
Cesnek, Michal
Votruba, Ivan
Krystof, Vladimir
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Shih, I-hung
Mabery, Eric
Mackman, Richard
Hasnik, Zbynek
Stefko, Martin
Tloustova, Eva
Tloust'Ova, Eva
Hrebabecky, Hubert
Clercq, Erik de
Horska, Kveta
Janeba, Zlatko
Meszarosova, Katerina
Naesens, Lieve
Sala, Michal
Dolakova, Petra
Nencka, Radim
Horejsi, Katerina
Chalupova, Sarka
Vrbovska, Silvie
Neyts, Johan
Vrbkova, Silvie
Solinova, Veronika
Kasicka, Vaclav
Dejmek, Milan
De Palma, Armando M.
Keough, Dianne T.
Guddat, Luke W.
Hebabecky, Hubert
Draeinsky, Martin
Cechova, Lucie
Baszczynski, Ondrej
Mertlikova-Kaiserova, Helena
Prochazkova, Eliska
Kolman, Viktor
Kostinova, Alexandra
Doleckova, Iva
Brynda, Jiri
Voller, Jiri
Luebbers, Thomas
Angehrn, Peter
Gmuender, Hans
Herzig, Silvia
Kulhanek, Josef
Articles
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Silhar, Peter;
Shih, I-hung;
Mabery, Eric;
Mackman, Richard, Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(5), 2329 - 2366, 10.1016/j.bmc.2007.11.067 
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Hocek, Michal;
Pohl, Radek;
Stefko, Martin, Synthesis of benzamide-C-ribonucleosides by Pd-catalyzed aminocarbonylations. Tetrahedron 2009, 65(23), 4471 - 4483, 10.1016/j.tet.2009.04.006 .
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Hocek, Michal;
Pohl, Radek;
Klepetarova, Blanka;
Hasnik, Zbynek, Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)-and 6-(carbamoylmethyl)purines. Collect. Czech. Chem. Commun. 2009, 74(7-8), 1035 - 1059, 10.1135/cccc2009042 .
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Holy, Antonin;
Masojidkova, Milena;
Meszarosova, Katerina, Synthesis of acyclic adenine 8,N-anhydronucleosides. Collect. Czech. Chem. Commun. 2000, 65(7), 1109 - 1125.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Tloustova, Eva, Synthesis and cytostatic activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N-substituted adenines, 2,6-diaminopurines and related compounds. Collect. Czech. Chem. Commun. 2001, 66(10), 1545 - 1592.
Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Naesens, Lieve, 6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity. Journal of Medicinal Chemistry 2002, 45(9), 1918 - 1929, 10.1021/jm011095y .
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Budesinsky, Milos;
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Synthesis of optically active N-alkyl derivatives of (R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds. Collect. Czech. Chem. Commun. 2003, 68(5), 931 - 950, 10.1135/cccc20030931 .
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Holy, Antonin;
Masojidkova, Milena;
Hrebabecky, Hubert, Synthesis of purine nucleoside analogues derived from carbocyclic 5-C-(hydroxymethyl)hexopyranoses. Collect. Czech. Chem. Commun. 2004, 69(2), 435 - 452.
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Synthesis of N- and N-[2-hydroxy-3- (phosphonomethoxy)-propyl] derivatives of N-substituted adenines, 2,6-diaminopurines and related compounds. Collect. Czech. Chem. Commun. 2004, 69(10), 1889 - 1913, 10.1135/cccc20041889 .
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Holy, Antonin;
Masojidkova, Milena;
Hrebabecky, Hubert, Synthesis of racemic 9-(6- and 2,6-substituted 9H-purin-9-yl)-5- oxatricyclo[4.2.1.0]nonane-3-methanols, novel conformationally locked carbocyclic nucleosides. Collect. Czech. Chem. Commun. 2005, 70(1), 103 - 123, 10.1135/cccc20050103 .
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Holy, Antonin;
Masojidkova, Milena;
Dolakova, Petra, Synthesis of Base Substituted 2-Hydroxy-3-(purin-9-yl)-propanoic Acids and 4-(Purin-9-yl)-3-butenoic Acids. Nucleosides, Nucleotides and Nucleic Acids 2003, 22(12), 2145 - 2160, 10.1081/NCN-120026636 .
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Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Tloust'Ova, Eva;
Hrebabecky, Hubert;
Horska, Kveta;
Nencka, Radim, Design and synthesis of novel 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase. Bioorganic and Medicinal Chemistry Letters 2006, 16(5), 1335 - 1337, 10.1016/j.bmcl.2005.11.050 .
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Holy, Antonin;
Masojidkova, Milena;
Hrebabecky, Hubert, Synthesis of novel conformationally locked carbocyclic nucleosides derived from 5,5- and 6,6-bis(hydroxymethyl)bicyclo[2.2.1]heptan-2-ol. Collect. Czech. Chem. Commun. 2005, 70(4), 519 - 538, 10.1135/cccc20050519 .
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Holy, Antonin;
Pohl, Radek;
Horejsi, Katerina, Tricyclic purine analogs derived from 2-amino-6-chloropurine and 2,6-diaminopurine and their methylated quaternary salts. Collect. Czech. Chem. Commun. 2006, 71(1), 77 - 90, 10.1135/cccc20060077 .
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Holy, Antonin;
Masojidkova, Milena;
Chalupova, Sarka, Synthesis of some N-substituted derivatives of 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, cidofovir). Collect. Czech. Chem. Commun. 2005, 70(12), 2053 - 2065, 10.1135/cccc20052053 .
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Holy, Antonin;
Masojidkova, Milena;
Chalupova, Sarka, Synthesis of N-substituted derivatives of 1-[2- (phosphonomethoxy)ethyl]cytosine and its diisopropyl ester as a model reaction for the synthesis of N-substituted derivatives of cidofovir. Collect. Czech. Chem. Commun. 2005, 70(12), 2066 - 2074, 10.1135/cccc20052066 .
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Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
Pohl, Radek;
Clercq, Erik de;
Horejsi, Katerina, Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity. Bioorganic and Medicinal Chemistry 2006, 14(23), 8057 - 8065, 10.1016/j.bmc.2006.07.036 .
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Holy, Antonin;
Masojidkova, Milena;
Pohl, Radek;
Vrbovska, Silvie, Bifunctional acyclic nucleoside phosphonates. 1. Symmetrical 1,3-bis[(phosphonomethoxy)propan-2-yl] derivatives of purines and pyrimidines. Collect. Czech. Chem. Commun. 2006, 71(4), 543 - 566, 10.1135/cccc20060543 .
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Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Preparation of C-5 substituted cidofovir derivatives. Collect. Czech. Chem. Commun. 2006, 71(4), 579 - 594, 10.1135/cccc20060579 .
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Holy, Antonin;
Masojidkova, Milena;
Hrebabecky, Hubert;
Sala, Michal, Synthesis of novel racemic conformationally locked carbocyclic nucleosides derived from 7-substituted bicyclo[2.2.1]hept-5-ene-2,2-dimethanols. Collect. Czech. Chem. Commun. 2006, 71(5), 635 - 649, 10.1135/cccc20060635 .
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Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Hrebabecky, Hubert, Synthesis of novel conformationally locked carbocyclic nucleosides derived from 3-(hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol. Collect. Czech. Chem. Commun. 2006, 71(6), 871 - 888, 10.1135/cccc20060871 .
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Holy, Antonin;
Dracinsky, Martin;
Vrbkova, Silvie, Bifunctional acyclic nucleoside phosphonates: synthesis of chiral 9-{3-hydroxy[1,4-bis(phosphonomethoxy)]butan-2-yl} derivatives of purines. Tetrahedron Asymmetry 2007, 18(18), 2233 - 2247, 10.1016/j.tetasy.2007.09.021 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert, Synthesis of novel carbocyclic nucleosides and pro-tides derived from 4-oxatricyclo[4.2.1.0]nonane-9-methanol. Collect. Czech. Chem. Commun. 2007, 72(10), 1331 - 1349, 10.1135/cccc20071331 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Dejmek, Milan, Synthesis of novel carbocyclic nucleoside analogues derived from 2-(hydroxymethyl)bicyclo[2.2.1]heptane. Collect. Czech. Chem. Commun. 2007, 72(11), 1523 - 1544, 10.1135/cccc20071523 .
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Holy, Antonin;
Dracinsky, Martin;
Vrbkova, Silvie, Bifunctional acyclic nucleoside phosphonates: 2. Symmetrical 2-{[bis(phosphono)methoxy]methyl}ethyl derivatives of purines and pyrimidines. Collect. Czech. Chem. Commun. 2007, 72(7), 965 - 983, 10.1135/cccc20070965 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert, Synthesis of novel carbocyclic nucleoside analogues containing bicyclo[2.2.1]hept-2-ene-2-methanol. Collect. Czech. Chem. Commun. 2008, 73(1), 44 - 58, 10.1135/cccc20080044 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Neyts, Johan;
De Palma, Armando M., Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol. Collect. Czech. Chem. Commun. 2009, 74(3), 487 - 502, 10.1135/cccc2008204 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Neyts, Johan;
De Palma, Armando M., Synthesis of novel racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.0]nonane- 9-methanol and 4-oxatricyclo[4.3.1.0]decane-10-methanol, compounds with activity against coxsackie viruses. Collect. Czech. Chem. Commun. 2009, 74(3), 469 - 485, 10.1135/cccc2008193 .
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Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Dolakova, Petra;
Solinova, Veronika;
Kasicka, Vaclav, Acyclic nucleoside bisphosphonates: Synthesis and properties of chiral 2-amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines. European Journal of Medicinal Chemistry 2009, 44(6), 2408 - 2424, 10.1016/j.ejmech.2008.09.031 .
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Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Hrebabecky, Hubert;
Sala, Michal;
Neyts, Johan;
De Palma, Armando M., Norbornane as the novel pseudoglycone moiety in nucleosides. Tetrahedron 2009, 65(45), 9291 - 9299, 10.1016/j.tet.2009.09.018 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert, New carbocyclic nucleoside analogues built on a bicyclo[2.2.2]octane-2,2- dimethanol template. Collect. Czech. Chem. Commun. 2009, 74(9), 1425 - 1441, 10.1135/cccc2009090 .
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Holy, Antonin;
Masojidkova, Milena;
Sala, Michal;
Neyts, Johan;
De Palma, Armando M.;
Hebabecky, Hubert;
Draeinsky, Martin, Synthesis of novel racemic carbocyclic nucleosides derived from 5,6-disubstituted norbornene. Collect. Czech. Chem. Commun. 2010, 75(1), 1 - 20, 10.1135/cccc2009116 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Balzarini, Jan;
Klepetarova, Blanka;
Clercq, Erik de;
Janeba, Zlatko;
Baszczynski, Ondrej, Synthesis and antiviral activity of N-[3-fluoro-2- (phosphonomethoxy)propyl] analogues derived from N-substituted adenines and 2,6-diaminopurines. Bioorganic and Medicinal Chemistry 2011, 19(7), 2114 - 2124, 10.1016/j.bmc.2011.02.050 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
Guddat, Luke W.;
Baszczynski, Ondrej, The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. European Journal of Medicinal Chemistry 2013, 67, 81 - 89, 10.1016/j.ejmech.2013.06.032 .
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Dracinsky, Martin;
Jansa, Petr;
Janeba, Zlatko;
Mertlikova-Kaiserova, Helena;
Kolman, Viktor;
Kostinova, Alexandra, Efficient synthesis and biological properties of the 2'-trifluoromethyl analogues of acyclic nucleosides and acyclic nucleoside phosphonates. Collect. Czech. Chem. Commun. 2011, 76(10), 1187 - 1198, 10.1135/cccc2011105 .
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Dracinsky, Martin;
Cesnek, Michal;
Krystof, Vladimir;
Janeba, Zlatko;
Doleckova, Iva;
Brynda, Jiri;
Voller, Jiri, Synthesis and biological evaluation of guanidino analogues of roscovitine. European Journal of Medicinal Chemistry 2013, 62, 443 - 452, 10.1016/j.ejmech.2013.01.021 .
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