Detail of compound @ czechem

Molecular Formula: C₂H₇N

Molecular weight: 45.08368

InChi: InChI=1S/C2H7N/c1-3-2/h3H,1-2H3

InChi Key: ROSDSFDQCJNGOL-UHFFFAOYSA-N

SMILES: N(C)C

Chemical Name
dimethyl amine
dimethyl-amine
Dimethylamine
N,N-dimethyl amine
N,N-dimethyl-amine
N,N-dimethylamine
N-methylmethanamine

External Links
PubChem

Authors of compound

Naus, Petr
Bures, Filip
Kulhanek, Jiri
Pytela, Oldrich
Ludwig, Miroslav
Ruzicka, Ales
Mikysek, Tomas
Ludvik, Jiri
Patak, Michal
Cermakova, Hana
Kuznik, Wojciech
Kityk, Iwan V.
Budesinsky, Milos
Holy, Antonin
Dracinsky, Martin
Parik, Patrik
Dvorakova, Hana
Machacek, Vladimir
Simunek, Petr
Jansa, Petr
Dvorak, Dalimil
Arnold, Zdenek
Zavada, Jiri
Stary, Ivo
Havranek, Miroslav
Wagner, Roman
Hocek, Michal
Rotrekl, Ivan
Drahonovsky, Dusan
Tobrman, Tomas
Meca, Ludek
Smidkova, Marketa
Votruba, Ivan
Kavalek, Jaromir
Sterba, Vojeslav
Bertolasi, Valerio
Lycka, Antonin
Potacek, Milan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Hockova, Dana
Stara, Irena G.
Stambasky, Jan
Pohl, Radek
Klepetarova, Blanka
Silhar, Peter
Shih, I-hung
Mabery, Eric
Mackman, Richard
Kuchar, Martin
Hasnik, Zbynek
Barta, Jan
Ernsting, Nikolaus P.
Slavetinska, Lenka
Dzubak, Petr
Hajduch, Marian
Kubelka, Tomas
Perlikova, Pavla
Konecny, Petr
Bahador, Gina
Tichy, Michal
Tloustova, Eva
Lee, Yu-Jen
Tloust'Ova, Eva
Weber, Jan
Caletkova, Olga
Bogdanova, Katerina
Kolar, Milan
Vrbkova, Jana
Tichy, Milos
Hrebabecky, Hubert
Janeba, Zlatko
Zidek, Zdenek
Naesens, Lieve
Kmonickova, Eva
Chalupova, Sarka
Kovackova, Sona
Robins, Morris J.
Lin, Xiaoyu
El Bahaie, Said
Jirman, Josef
Fiedler, Pavel
Paleta, Oldrich
Kvicala, Jaroslav
Pelter, Andrew
Plocar, Jakub
Vlasakova, Ruzena
Valaskova, Pavla
Pospisil, Jiri
Pulst, M.
Potacek, M.

Articles

Bures, Filip; Kulhanek, Jiri; Pytela, Oldrich; Ruzicka, Ales; Mikysek, Tomas; Ludvik, Jiri, Push-pull molecules with a systematically extended π-conjugated system featuring 4,5-dicyanoimidazole. Dyes and Pigments 2010, 85(1-2), 57 - 65, 10.1016/j.dyepig.2009.10.004

Bures, Filip; Pytela, Oldrich; Patak, Michal, Tartrate- and imidazole-derived diketones and diols: Preparation and stability constants of their Cu complexes. Monatshefte fur Chemie 2011, 142(11), 1131 - 1136, 10.1007/s00706-011-0588-1

Bures, Filip; Kulhanek, Jiri; Ludwig, Miroslav; Ruzicka, Ales; Mikysek, Tomas; Cermakova, Hana; Kuznik, Wojciech; Kityk, Iwan V., Structure-property relationships and nonlinear optical effects in donor-substituted dicyanopyrazine-derived push-pull chromophores with enlarged and varied π-linkers. European Journal of Organic Chemistry 2012(3), 529 - 538, 10.1002/ejoc.201101226

Dvorak, Dalimil; Arnold, Zdenek, REACTION OF ARYLMETHYLENEMALONALDEHYDES WITH SOME NUCLEOPHILES. Collect. Czech. Chem. Commun. 1987, 52(11), 2699 - 2709.

Dvorak, Dalimil; Arnold, Zdenek; Havranek, Miroslav, Convenient preparation of 1,3-bis(dimethylamino)-trimethinium perchlorate, tetrafluoroborate and hexafluorophosphate. Collect. Czech. Chem. Commun. 1996, 61(11), 1637 - 1641, 10.1135/cccc19961637

Kulhanek, Jiri; Ludwig, Miroslav; Parik, Patrik; Dvorak, Dalimil; Wagner, Roman; Rotrekl, Ivan; Drahonovsky, Dusan; Tobrman, Tomas; Meca, Ludek; Smidkova, Marketa, Acidity of benzoic acids bearing the (CO)Cr=CN(CH ) group. Organometallics 2010, 29(18), 4135 - 4138, 10.1021/om100608x

Hocek, Michal; Hockova, Dana; Stambasky, Jan, Cytostatic 6-arylpurine nucleosides V. synthesis of 8-substituted 6-phenylpurine ribonucleosides. Collect. Czech. Chem. Commun. 2003, 68(5), 837 - 848, 10.1135/cccc20030837

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Kuchar, Martin, Synthesis of purines bearing functionalized C-substituents by the conjugate addition of nucleophiles to 6-vinylpurines and 6-ethynylpurines. European Journal of Organic Chemistry 2006(22), 5083 - 5098, 10.1002/ejoc.200600545

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Shih, I-hung; Mabery, Eric; Mackman, Richard; Kuchar, Martin, Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(3), 1400 - 1424, 10.1016/j.bmc.2007.10.063

Hocek, Michal; Pohl, Radek; Klepetarova, Blanka; Barta, Jan; Ernsting, Nikolaus P., Modular synthesis of 5-substituted thiophen-2-yl C-2′- deoxyribonucleosides. Journal of Organic Chemistry 2008, 73(10), 3798 - 3806, 10.1021/jo800177y

Hocek, Michal; Votruba, Ivan; Pohl, Radek; Silhar, Peter; Shih, I-hung; Mabery, Eric; Mackman, Richard, Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(5), 2329 - 2366, 10.1016/j.bmc.2007.11.067

Hocek, Michal; Pohl, Radek; Klepetarova, Blanka; Hasnik, Zbynek, Synthesis of (purin-6-yl)acetates and their transformations to 6-(2-hydroxyethyl)-and 6-(carbamoylmethyl)purines. Collect. Czech. Chem. Commun. 2009, 74(7-8), 1035 - 1059, 10.1135/cccc2009042

Naus, Petr; Hocek, Michal; Pohl, Radek; Perlikova, Pavla, Sugar-modified derivatives of cytostatic 6-(het)aryl-7-deazapurine nucleosides: 2′-c-methylribonucleosides, arabinonucleosides and 2′-deoxy-2′-fluoroarabinonucleosides. Collect. Czech. Chem. Commun. 2011, 76(8), 957 - 988, 10.1135/cccc2011082

Hocek, Michal; Slavetinska, Lenka; Kubelka, Tomas, Synthesis of substituted benzyl homo-C-ribonucleosides and -nucleotides as carba analogues of phosphoribosylanthranilate. European Journal of Organic Chemistry 2012(26), 4969 - 4981, 10.1002/ejoc.201200819

Hocek, Michal; Pohl, Radek; Bahador, Gina; Tichy, Michal; Lee, Yu-Jen; Tloust'Ova, Eva; Weber, Jan, Synthesis and biological activity of benzo-fused 7-deazaadenosine analogues. 5- and 6-substituted 4-amino- or 4-alkylpyrimido[4,5-b]indole ribonucleosides. Bioorganic and Medicinal Chemistry 2013, 21(17), 5362 - 5372, 10.1016/j.bmc.2013.06.011

Naus, Petr; Hocek, Michal; Slavetinska, Lenka; Dzubak, Petr; Hajduch, Marian; Perlikova, Pavla; Konecny, Petr; Tloust'Ova, Eva; Caletkova, Olga; Bogdanova, Katerina; Kolar, Milan; Vrbkova, Jana, Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides. Journal of Medicinal Chemistry 2014, 57(3), 1097 - 1110, 10.1021/jm4018948

Holy, Antonin; Dvorakova, Hana; Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL)DERIVATIVES OF PURINE AND PYRIMIDINE BASES. II. THE SYNTHON APPROACH. Collect. Czech. Chem. Commun. 1995, 60(8), 1390 - 1409, 10.1135/cccc19951390

Holy, Antonin; Hrebabecky, Hubert, Preparation of thymidine-4′-C-carboxylic acid and its derivatives. Collect. Czech. Chem. Commun. 1997, 62(7), 1128 - 1135.

Holy, Antonin; Masojidkova, Milena; Janeba, Zlatko, Synthesis of 8-amino-and N-substituted 8-aminoadenine derivatives of acyclic nucleoside and nucleotide analogs. Collect. Czech. Chem. Commun. 2001, 66(3), 517 - 532, 10.1135/cccc20010517

Holy, Antonin; Votruba, Ivan; Masojidkova, Milena; Tloustova, Eva, Synthesis and cytostatic activity of N-[2-(phosphonomethoxy)alkyl] derivatives of N-substituted adenines, 2,6-diaminopurines and related compounds. Collect. Czech. Chem. Commun. 2001, 66(10), 1545 - 1592.

Holy, Antonin; Votruba, Ivan; Masojidkova, Milena; Andrei, Graciela; Snoeck, Robert; Balzarini, Jan; De Clercq, Erik; Naesens, Lieve, 6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity. Journal of Medicinal Chemistry 2002, 45(9), 1918 - 1929, 10.1021/jm011095y

Holy, Antonin; Masojidkova, Milena; Chalupova, Sarka, Synthesis of N-substituted derivatives of 1-[2- (phosphonomethoxy)ethyl]cytosine and its diisopropyl ester as a model reaction for the synthesis of N-substituted derivatives of cidofovir. Collect. Czech. Chem. Commun. 2005, 70(12), 2066 - 2074, 10.1135/cccc20052066

Budesinsky, Milos; Holy, Antonin; Dracinsky, Martin; Jansa, Petr; Kovackova, Sona, Isotopic exchange of hydrogen at C-5 in pyrimidine derivatives: tautomers with an sp-hybridised C-5 carbon atom. European Journal of Organic Chemistry 2009(24), 4117 - 4122, 10.1002/ejoc.200900529

Holy, Antonin; Masojidkova, Milena; Janeba, Zlatko, Alternative synthesis of 9-{3-[(diisopropoxyphosphoryl)-methoxy]-2- hydroxypropyl}adenine and its free phosphonates substituted at the c-8 position of purine base. Collect. Czech. Chem. Commun. 2010, 75(3), 371 - 381, 10.1135/cccc2009569

Janeba, Zlatko; Robins, Morris J.; Lin, Xiaoyu, Functionalization of Guanosine and 2′-Deoxyguanosine at C6: A Modified Appel Process and SAr Displacement of Imidazole. Nucleosides, Nucleotides and Nucleic Acids 2004, 23(1-2), 137 - 147, 10.1081/NCN-120027823

Kavalek, Jaromir; Sterba, Vojeslav; El Bahaie, Said, KINETICS AND MECHANISM OF METHANOLYSIS OF BENZOYL DERIVATIVES OF SUBSTITUTED PHENYLUREAS AND PHENYLTHIOUREAS. Collect. Czech. Chem. Commun. 1984, 49(9), 2103 - 2110.

Machacek, Vladimir; Kavalek, Jaromir; Sterba, Vojeslav; Jirman, Josef, AN ANOMALOUS EFFECT OF METHYL GROUP ON ACIDITY OF ACYLTHIOUREAS. Collect. Czech. Chem. Commun. 1987, 52(8), 1992 - 1998.

Paleta, Oldrich; Kvicala, Jaroslav; Pelter, Andrew; Plocar, Jakub; Vlasakova, Ruzena, 2-Fluoro-2-buten-4-olide, a New Fluorinated Synthon. Preparation; 1,2-, 1,4- And Tandem Additions. Synlett 1997, 1997(8), 986 - 988.

Pytela, Oldrich; Ludwig, Miroslav; Valaskova, Pavla, KINETICS AND MECHANISM OF ACID CATALYZED DECOMPOSITION OF 1-PHENYL-3,3-DIALKYLTRIAZENES. Collect. Czech. Chem. Commun. 1994, 59(2), 401 - 411, 10.1135/cccc19940401

Machacek, Vladimir; Simunek, Petr; Bertolasi, Valerio; Lycka, Antonin, An NMR and X-ray study of the structure of the azo coupling product of 4-dimethylaminopent-3-en-2-one and benzenediazonium-tetrafluoroborate. Organic and Biomolecular Chemistry 2003, 1(18), 3250 - 3256, 10.1039/b303206j

Potacek, Milan; Pospisil, Jiri, Microwave-assisted solvent-free intramolecular 1,3-dipolar cycloaddition reactions leading to hexahydrochromeno[4,3-b]pyrroles: scope and limitations. Tetrahedron 2007, 63(2), 337 - 346, 10.1016/j.tet.2006.10.074

Pulst, M.; Potacek, M., Contributions to Synthesis of Enaminothioketones. J. Prakt. Chem. (Leipzig) 1988, 330(4), 665 - 670.

Zavada, Jiri; Stary, Ivo; Stara, Irena G., Nucleophilic Cleavage of 4,5-Dihydro-3H-dinaphth<2,1-c:1',2'-e>azepinium Quaternary Salts. A Convenient Approach to New Axially Dissymmetric and Axially Asymmetric Ligands. Journal of Organic Chemistry 1992, 57(25), 6966 - 6969, 10.1021/jo00051a053

Zavada, Jiri; Stary, Ivo; Stara, Irena G.; Tichy, Milos; Fiedler, Pavel, Nucleophilic Attack on 4,5-Dihydro-4-alkyl-3H-dinaphtho<2,1-c:1',2'-e>thiepinium Salts. A Convenient Approach to New 2,2'-Bidentate 1,1'-Binaphthalene Ligands with Sulfur Donor Atoms. Journal of Organic Chemistry 1994, 59(6), 1326 - 1332, 10.1021/jo00085a021

Patents

Holy, Antonin; Jansa, Petr; Janeba, Zlatko; Zidek, Zdenek; Kmonickova, Eva, PYRIMIDINE COMPOUNDS INHIBITING THE FORMATION OF NITRIC OXIDE AND PROSTAGLANDIN E2, METHOD OF PRODUCTION THEREOF AND USE THEREOF, WO2012/116666, 2012.