Molecular Formula: C5H6N2O2
Molecular weight: 126.11334
InChi: InChI=1S/C5H6N2O2/c1-9-4-2-3-6-5(8)7-4/h2-3H,1H3,(H,6,7,8)
InChi Key: BLYYQDFZPGAAQM-UHFFFAOYSA-N
SMILES: c1(nc(=O)[nH]cc1)OC
Chemical Name
4-Methoxy pyrimidin-2-one
4-methoxy-1H-pyrimidin-2-one
4-methoxy-2(1H)-pyrimidinone
4-methoxy-2-pyrimidone
4-methoxypyrimidin-2(1H)-one
4-methoxypyrimidin-2-one
O4-methyluracil
4-Methoxy pyrimidin-2-one
4-methoxy-1H-pyrimidin-2-one
4-methoxy-2(1H)-pyrimidinone
4-methoxy-2-pyrimidone
4-methoxypyrimidin-2(1H)-one
4-methoxypyrimidin-2-one
O4-methyluracil
Authors of compound
Budesinsky, Milos
Holy, Antonin
Jindrich, Jindrich
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Saman, David
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
Kolehmainen, Erkki
Pohl, Radek
Rosenberg, Ivan
Clercq, Erik de
Alexander, Petr
Spassova, Maria
Guenter, Jaroslav
Janeba, Zlatko
Lappalainen, Kari
Pomeisl, Karel
Chalupova, Sarka
Chocholouasova, Jana
Vacek, Jaroslav
Kovackova, Soaa
Antonin, Holy
Jan Marie Rene, Balzarini
Hana, Dvorakova
Erik Desire Alice, De Clercq
Holy, Antonin
Jindrich, Jindrich
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Saman, David
Votruba, Ivan
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
Kolehmainen, Erkki
Pohl, Radek
Rosenberg, Ivan
Clercq, Erik de
Alexander, Petr
Spassova, Maria
Guenter, Jaroslav
Janeba, Zlatko
Lappalainen, Kari
Pomeisl, Karel
Chalupova, Sarka
Chocholouasova, Jana
Vacek, Jaroslav
Kovackova, Soaa
Antonin, Holy
Jan Marie Rene, Balzarini
Hana, Dvorakova
Erik Desire Alice, De Clercq
Articles
Holy, Antonin;
Dvorakova, Hana;
Rosenberg, Ivan, SYNTHESIS OF N-(2-(2-PHOSPHONYLETHOXY)ETHYL) DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1990, 55(3), 809 - 818.
Holy, Antonin;
Dvorakova, Hana;
Rosenberg, Ivan, SYNTHESIS OF (3-HYDROXY-2-PHOSPHONYLMETHOXYPROPYL) DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1989, 54(9), 2470 - 2501.
Holy, Antonin;
Jindrich, Jindrich;
Dvorakova, Hana, SYNTHESIS OF ISOMERIC N-(3-FLUORO-2-HYDROXYPROPYL) AND N-(2-FLUORO-3-HYDROXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. Collect. Czech. Chem. Commun. 1992, 57(7), 1466 - 1482, 10.1135/cccc19921466 
.
.
Holy, Antonin, SYNTHESES OF ENANTIOMERIC N-(3-HYDROXY-2-PHOSPHONOMETHOXYPROPYL)DERIVATIVES OF PURINE AND PYRIMIDINE BASES. Collect. Czech. Chem. Commun. 1993, 58(3), 649 - 674, 10.1135/cccc19930649 .
.
Holy, Antonin;
Alexander, Petr, GENERAL METHOD OF PREPARATION OF N-<(S)-(3-HYDROXY-2-PHOSPHONOMETHOXYPROPYL)> DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1993, 58, 1151 - 1163, 10.1135/cccc19931151 .
.
Budesinsky, Milos;
Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena;
Spassova, Maria, SYNTHEIS OF N-(3-AZIDO-2-HYDROXYPROPYL), N-(3-PHTHALIMIDO-2-HYDROXYPROPYL) AND N-(3-AMINO-2-HYDROXYPROPYL)DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1994, 59(5), 1153 - 1174, 10.1135/cccc19941153 .
.
Holy, Antonin;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. I. THE STEPWISE APPROACH. Collect. Czech. Chem. Commun. 1995, 60(7), 1196 - 1212, 10.1135/cccc19951196 .
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Holy, Antonin;
Saman, David;
Kolehmainen, Erkki;
Guenter, Jaroslav;
Lappalainen, Kari, C and N NMR chemical shift assignments of N-1-(2-azidoethyl)-4-R-pyrimidin-2-ones by H,X HMQ(B)C with z-gradient selection. Magn. Reson. Chem. 1998, 36(6), 442 - 444.
Holy, Antonin;
Masojidkova, Milena;
Chalupova, Sarka, Synthesis of some N-substituted derivatives of 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, cidofovir). Collect. Czech. Chem. Commun. 2005, 70(12), 2053 - 2065, 10.1135/cccc20052053 .
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Holy, Antonin;
Votruba, Ivan;
Pohl, Radek;
Pomeisl, Karel, Syntheses of base and side-chain modified pyrimidine 1-[2- (phosphonomethoxy)propyl] derivatives as potent inhibitors of thymidine phosphorylase (PD-ECGF) from SD-lymphoma. Collect. Czech. Chem. Commun. 2006, 71(4), 595 - 624, 10.1135/cccc20060595 .
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Holy, Antonin;
Pohl, Radek;
Pomeisl, Karel, Pd-catalyzed Suzuki-Miyaura coupling reactions in the synthesis of 5-aryl-1-[2-(phosphonomethoxy)ethyl]uracils as potential multisubstrate inhibitors of thymidine phosphorylase. Tetrahedron Letters 2007, 48(17), 3065 - 3067, 10.1016/j.tetlet.2007.02.107 .
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Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Pohl, Radek;
Clercq, Erik de;
Janeba, Zlatko, Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base. Canadian Journal of Chemistry 2010, 88(7), 628 - 638, 10.1139/V10-054 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Chocholouasova, Jana;
Vacek, Jaroslav;
Kovackova, Soaa, Mechanism of the isotopic exchange reaction of the 5-H hydrogen of uracil derivatives in water and nonprotic solvents. European Journal of Organic Chemistry 2011(4), 777 - 785, 10.1002/ejoc.201001335 .
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