Molecular Formula: C4H5N3O
Molecular weight: 111.102
InChi: InChI=1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)
InChi Key: OPTASPLRGRRNAP-UHFFFAOYSA-N
SMILES: n1c(=O)[nH]ccc1N
Chemical Name
4-aminopyrimidin-2-one
C
cysn
Cyt
cytosine
L-cytosine
[3H]-Cytosine
4-aminopyrimidin-2-one
C
cysn
Cyt
cytosine
L-cytosine
[3H]-Cytosine
Authors of compound
Budesinsky, Milos
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Saman, David
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Kolehmainen, Erkki
Pohl, Radek
Rosenberg, Ivan
Liboska, Radek
Alexander, Petr
Spassova, Maria
Guenter, Jaroslav
Lappalainen, Kari
Vrbovska, Silvie
Vrbkova, Silvie
Chocholouasova, Jana
Vacek, Jaroslav
Kovackova, Soaa
Rejman, Dominik
Kocalka, Petr
Vanek, Vaclav
Rinnova, Marketa
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Jansa, Petr
Saman, David
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Kolehmainen, Erkki
Pohl, Radek
Rosenberg, Ivan
Liboska, Radek
Alexander, Petr
Spassova, Maria
Guenter, Jaroslav
Lappalainen, Kari
Vrbovska, Silvie
Vrbkova, Silvie
Chocholouasova, Jana
Vacek, Jaroslav
Kovackova, Soaa
Rejman, Dominik
Kocalka, Petr
Vanek, Vaclav
Rinnova, Marketa
Articles
Holy, Antonin;
Dvorakova, Hana;
Rosenberg, Ivan, SYNTHESIS OF N-(2-PHOSPHONYLMETHOXYETHYL) DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1989, 54(8), 2190 - 2210.
Holy, Antonin, SYNTHESES OF ENANTIOMERIC N-(3-HYDROXY-2-PHOSPHONOMETHOXYPROPYL)DERIVATIVES OF PURINE AND PYRIMIDINE BASES. Collect. Czech. Chem. Commun. 1993, 58(3), 649 - 674, 10.1135/cccc19930649 
.
.
Holy, Antonin;
Alexander, Petr, GENERAL METHOD OF PREPARATION OF N-<(S)-(3-HYDROXY-2-PHOSPHONOMETHOXYPROPYL)> DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1993, 58, 1151 - 1163, 10.1135/cccc19931151 .
.
Budesinsky, Milos;
Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena;
Spassova, Maria, SYNTHEIS OF N-(3-AZIDO-2-HYDROXYPROPYL), N-(3-PHTHALIMIDO-2-HYDROXYPROPYL) AND N-(3-AMINO-2-HYDROXYPROPYL)DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1994, 59(5), 1153 - 1174, 10.1135/cccc19941153 .
.
Holy, Antonin;
Masojidkova, Milena, SYNTHESIS OF ENANTIOMERIC N-(2-PHOSPHONOMETHOXYPROPYL) DERIVATIVES OF PURINE AND PYRIMIDINE BASES. I. THE STEPWISE APPROACH. Collect. Czech. Chem. Commun. 1995, 60(7), 1196 - 1212, 10.1135/cccc19951196 .
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Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik, Synthesis of 2'-aminomethyl derivatives of N-(2- (phosphonomethoxy)ethyl) nucleotide analogues as potential antiviral agents. Journal of Medicinal Chemistry 1996, 39(17), 3263 - 3268, 10.1021/jm9601314 .
.
Holy, Antonin;
Dvorakova, Hana;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Guenter, Jaroslav, Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base. Journal of Medicinal Chemistry 1999, 42(12), 2064 - 2086, 10.1021/jm9811256 .
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Holy, Antonin;
Saman, David;
Kolehmainen, Erkki;
Guenter, Jaroslav;
Lappalainen, Kari, C and N NMR chemical shift assignments of N-1-(2-azidoethyl)-4-R-pyrimidin-2-ones by H,X HMQ(B)C with z-gradient selection. Magn. Reson. Chem. 1998, 36(6), 442 - 444.
Budesinsky, Milos;
Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Synthesis of optically active N-alkyl derivatives of (R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds. Collect. Czech. Chem. Commun. 2003, 68(5), 931 - 950, 10.1135/cccc20030931 .
.
Holy, Antonin;
Masojidkova, Milena;
Pohl, Radek;
Vrbovska, Silvie, Bifunctional acyclic nucleoside phosphonates. 1. Symmetrical 1,3-bis[(phosphonomethoxy)propan-2-yl] derivatives of purines and pyrimidines. Collect. Czech. Chem. Commun. 2006, 71(4), 543 - 566, 10.1135/cccc20060543 .
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Holy, Antonin;
Dracinsky, Martin;
Vrbkova, Silvie, Bifunctional acyclic nucleoside phosphonates: 2. Symmetrical 2-{[bis(phosphono)methoxy]methyl}ethyl derivatives of purines and pyrimidines. Collect. Czech. Chem. Commun. 2007, 72(7), 965 - 983, 10.1135/cccc20070965 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Chocholouasova, Jana;
Vacek, Jaroslav;
Kovackova, Soaa, Mechanism of the isotopic exchange reaction of the 5-H hydrogen of uracil derivatives in water and nonprotic solvents. European Journal of Organic Chemistry 2011(4), 777 - 785, 10.1002/ejoc.201001335 .
.
Masojidkova, Milena;
Rosenberg, Ivan;
Liboska, Radek, Carbocyclic phosphonate-based nucleotide analogs related to PMEA II. Racemic cis-configured derivatives. Collect. Czech. Chem. Commun. 1996, 61(5), 778 - 790, 10.1135/cccc19960778 .
.
Masojidkova, Milena;
Rosenberg, Ivan;
Liboska, Radek, Carbocyclic phosphonate-based nucleotide analogs related to pmea. I. Racemic trans-configured derivatives. Collect. Czech. Chem. Commun. 1996, 61(2), 313 - 332, 10.1135/cccc19960313 .
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