Molecular Formula: C8H12N3O5P
Molecular weight: 261.171741
InChi: InChI=1S/C8H12N3O5P/c9-7-1-2-11(8(12)10-7)3-6-4-16-17(13,14)5-15-6/h1-2,6H,3-5H2,(H,13,14)(H2,9,10,12)/t6-/m0/s1
InChi Key: YXQUGSXUDFTPLL-LURJTMIESA-N
SMILES: n1(c(=O)nc(cc1)N)C[C@@H]1OCP(=O)(OC1)O
Chemical Name
(S)-cHPMPC
cCDV
cyclic (S)-HPMPC
cyclic cidofovir
cyclic HPMPC
Cyclic-HPMPC
[14C]-Cyclic-HPMPC
(S)-cHPMPC
cCDV
cyclic (S)-HPMPC
cyclic cidofovir
cyclic HPMPC
Cyclic-HPMPC
[14C]-Cyclic-HPMPC
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Pohl, Radek
Rosenberg, Ivan
Naesens, Lieve
Keith, Kathy A.
Hitchcock, Michael J. M.
Lee, William A.
Kern, Earl R.
Naesens
Lenaerts
Andrei
Snoeck
Van Beers
Piskala, Alois
Neyts, Johan
Lebeau, Ilya
Duraffour, Sophie
Van Den Oord, Joost
De Vos, Rita
Crance, Jean-Marc
Garin, Daniel
Tichy, Tomas
Holy, Antonin
Dracinsky, Martin
Dvorakova, Hana
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Pohl, Radek
Rosenberg, Ivan
Naesens, Lieve
Keith, Kathy A.
Hitchcock, Michael J. M.
Lee, William A.
Kern, Earl R.
Naesens
Lenaerts
Andrei
Snoeck
Van Beers
Piskala, Alois
Neyts, Johan
Lebeau, Ilya
Duraffour, Sophie
Van Den Oord, Joost
De Vos, Rita
Crance, Jean-Marc
Garin, Daniel
Tichy, Tomas
Articles
Holy, Antonin;
Dvorakova, Hana;
Rosenberg, Ivan, SYNTHESIS OF (3-HYDROXY-2-PHOSPHONYLMETHOXYPROPYL) DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1989, 54(9), 2470 - 2501.
Holy, Antonin, Simple method for cleavage of phosphonic acid diesters to monoesters. Synthesis 1998(4), 381 - 385.
Holy, Antonin;
Keith, Kathy A.;
Hitchcock, Michael J. M.;
Lee, William A.;
Kern, Earl R., Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication. Antimicrobial Agents and Chemotherapy 2003, 47(7), 2193 - 2198, 10.1128/AAC.47.7.2193-2198.2003 
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.
Holy, Antonin;
Balzarini, Jan;
De Clercq, Erik;
Naesens;
Lenaerts;
Andrei;
Snoeck;
Van Beers, Antiadenovirus activities of several classes of nucleoside and nucleotide analogues. Antimicrobial Agents and Chemotherapy 2005, 49(3), 1010 - 1016, 10.1128/AAC.49.3.1010-1016.2005 .
.
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Lebeau, Ilya, Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains. Antimicrobial Agents and Chemotherapy 2007, 51(6), 2268 - 2273, 10.1128/AAC.01422-06 .
.
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Duraffour, Sophie;
Van Den Oord, Joost;
De Vos, Rita;
Crance, Jean-Marc;
Garin, Daniel, Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models. Antimicrobial Agents and Chemotherapy 2007, 51(12), 4410 - 4419, 10.1128/AAC.00838-07 .
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Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Naesens, Lieve;
Neyts, Johan, Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5- azacytosine: Synthesis and antiviral activity. Journal of Medicinal Chemistry 2007, 50(23), 5765 - 5772, 10.1021/jm0707166 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Tichy, Tomas, New prodrugs of Adefovir and Cidofovir. Bioorganic and Medicinal Chemistry 2011, 19(11), 3527 - 3539, 10.1016/j.bmc.2011.04.016 .
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Krecmerova, Marcela;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
Pohl, Radek, N-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: Chemistry and antiviral activity. Bioorganic and Medicinal Chemistry 2014, 22(10), 2896 - 2906, 10.1016/j.bmc.2014.03.031 .
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