Molecular Formula: C9H15N6O5P
Molecular weight: 318.226361
InChi: InChI=1S/C9H15N6O5P/c10-7-6-8(14-9(11)13-7)15(3-12-6)1-5(2-16)20-4-21(17,18)19/h3,5,16H,1-2,4H2,(H2,17,18,19)(H4,10,11,13,14)/t5-/m0/s1
InChi Key: XGTJCNSZEASLLL-YFKPBYRVSA-N
SMILES: c12c(c(nc(n2)N)N)ncn1C[C@H](OCP(=O)(O)O)CO
Chemical Name
(S)-(((1-(2,6-diamino-9H-purin-9-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid
(S)-1-(3-hydroxy-2-phosphonomethoxypropyl)-2,6-diaminopurine
(S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)-2,6-diaminopurine
(S)-9-[3-hydroxy-2-(phoshonomethoxy)propyl]-2,6-diaminopurine
(S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine
(S)-HPMPDAP
9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine
(S)-(((1-(2,6-diamino-9H-purin-9-yl)-3-hydroxypropan-2-yl)oxy)methyl)phosphonic acid
(S)-1-(3-hydroxy-2-phosphonomethoxypropyl)-2,6-diaminopurine
(S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)-2,6-diaminopurine
(S)-9-[3-hydroxy-2-(phoshonomethoxy)propyl]-2,6-diaminopurine
(S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine
(S)-HPMPDAP
9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine
Authors of compound
Krecmerova, Marcela
Holy, Antonin
Dracinsky, Martin
Jansa, Petr
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Pohl, Radek
Cihlar, Tomas
Alexander, Petr
Janeba, Zlatko
Naesens, Lieve
Pomeisl, Karel
Neyts, Johan
Lebeau, Ilya
Duraffour, Sophie
Van Den Oord, Joost
De Vos, Rita
Crance, Jean-Marc
Garin, Daniel
Tichy, Tomas
Brehova, Petra
Laflamme, Genevieve
Hui, Hon
Baszczynski, Ondrej
Prochazkova, Eliska
Vavrova, Katerina
Hrabalek, Alexandr
Skolova, Barbora
Roh, Jaroslav
Diblikova, Denisa
Kopecna, Monika
Holy, Antonin
Dracinsky, Martin
Jansa, Petr
Masojidkova, Milena
Andrei, Graciela
Snoeck, Robert
Balzarini, Jan
De Clercq, Erik
Pohl, Radek
Cihlar, Tomas
Alexander, Petr
Janeba, Zlatko
Naesens, Lieve
Pomeisl, Karel
Neyts, Johan
Lebeau, Ilya
Duraffour, Sophie
Van Den Oord, Joost
De Vos, Rita
Crance, Jean-Marc
Garin, Daniel
Tichy, Tomas
Brehova, Petra
Laflamme, Genevieve
Hui, Hon
Baszczynski, Ondrej
Prochazkova, Eliska
Vavrova, Katerina
Hrabalek, Alexandr
Skolova, Barbora
Roh, Jaroslav
Diblikova, Denisa
Kopecna, Monika
Articles
Holy, Antonin;
Alexander, Petr, GENERAL METHOD OF PREPARATION OF N-<(S)-(3-HYDROXY-2-PHOSPHONOMETHOXYPROPYL)> DERIVATIVES OF HETEROCYCLIC BASES. Collect. Czech. Chem. Commun. 1993, 58, 1151 - 1163, 10.1135/cccc19931151 
.
.
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Lebeau, Ilya, Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains. Antimicrobial Agents and Chemotherapy 2007, 51(6), 2268 - 2273, 10.1128/AAC.01422-06 .
.
Krecmerova, Marcela;
Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
De Clercq, Erik;
Duraffour, Sophie;
Van Den Oord, Joost;
De Vos, Rita;
Crance, Jean-Marc;
Garin, Daniel, Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models. Antimicrobial Agents and Chemotherapy 2007, 51(12), 4410 - 4419, 10.1128/AAC.00838-07 .
.
Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Cihlar, Tomas;
Naesens, Lieve;
Pomeisl, Karel;
Neyts, Johan;
Tichy, Tomas;
Brehova, Petra;
Laflamme, Genevieve;
Hui, Hon, Synthesis of ester prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] -2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. Journal of Medicinal Chemistry 2010, 53(19), 6825 - 6837, 10.1021/jm901828c .
.