Bioorganic and Medicinal Chemistry
ISSN:
0968-0896
Articles
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Shih, I-hung;
Mabery, Eric;
Mackman, Richard;
Kuchar, Martin, Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(3), 1400 - 1424, 10.1016/j.bmc.2007.10.063 
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Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Silhar, Peter;
Shih, I-hung;
Mabery, Eric;
Mackman, Richard, Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides. Bioorganic and Medicinal Chemistry 2008, 16(5), 2329 - 2366, 10.1016/j.bmc.2007.11.067 .
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Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Birkus, Gabriel;
Cihlar, Tomas;
Perlikova, Pavla;
Shih, Robert, Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides. Bioorganic and Medicinal Chemistry 2011, 19(1), 229 - 242, 10.1016/j.bmc.2010.11.029 .
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Hocek, Michal;
Pohl, Radek;
Tichy, Michal;
Xu, Hao Ying;
Chen, Yen-Liang;
Yokokawa, Fumiaki;
Shi, Pei-Yong, Synthesis and antiviral activity of 4,6-disubstituted pyrimido[4,5-b]indole ribonucleosides. Bioorganic and Medicinal Chemistry 2012, 20(20), 6123 - 6133,11, 10.1016/j.bmc.2012.08.021 .
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Holy, Antonin;
Masojidkova, Milena;
Zidek, Zdenek;
Kmonickova, Eva;
Dolakova, Petra, Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivatives. Bioorganic and Medicinal Chemistry 2005, 13(7), 2349 - 2354, 10.1016/j.bmc.2005.01.054 .
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Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena;
Zidek, Zdenek, Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6- guanidinopurines and their influence on the NO-production in macrophages. Bioorganic and Medicinal Chemistry 2005, 13(8), 2917 - 2926, 10.1016/j.bmc.2005.02.008 .
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Holy, Antonin;
Votruba, Ivan;
Masojidkova, Milena;
Otmar, Miroslav, Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9- deazapurine and related compounds. Bioorganic and Medicinal Chemistry 2004, 12(12), 3187 - 3195, 10.1016/j.bmc.2004.04.003 .
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Holy, Antonin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Hockova, Dana, Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2- (phosphonomethoxy)ethoxy]pyrimidine and related compounds. Bioorganic and Medicinal Chemistry 2004, 12(12), 3197 - 3202, 10.1016/j.bmc.2004.04.002 .
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Holy, Antonin;
Andrei, Graciela;
Snoeck, Robert;
Pohl, Radek;
Clercq, Erik de;
Horejsi, Katerina, Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity. Bioorganic and Medicinal Chemistry 2006, 14(23), 8057 - 8065, 10.1016/j.bmc.2006.07.036 .
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Holy, Antonin;
Cesnek, Michal;
Masojidkova, Milena;
Zidek, Zdenek;
Kmonickova, Eva, Synthesis of guanidino analogues of PMPDAP and their immunobiological activity. Bioorganic and Medicinal Chemistry 2008, 16(2), 965 - 980, 10.1016/j.bmc.2007.10.010 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin, Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy. Bioorganic and Medicinal Chemistry 2008, 16(14), 6778 - 6782, 10.1016/j.bmc.2008.05.058 .
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Krecmerova, Marcela;
Holy, Antonin;
Masojidkova, Milena, Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position. Bioorganic and Medicinal Chemistry 2010, 18(1), 387 - 395, 10.1016/j.bmc.2009.10.044 .
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Holy, Antonin;
Dracinsky, Martin;
Hrebabecky, Hubert;
Sala, Michal;
Nencka, Radim;
Neyts, Johan;
De Palma, Armando M.;
Leyssen, Pieter, Design, synthesis, and biological evaluation of novel coxsackievirus B3 inhibitors. Bioorganic and Medicinal Chemistry 2010, 18(12), 4374 - 4384, 10.1016/j.bmc.2010.04.081 .
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Holy, Antonin;
Masojidkova, Milena;
Hockova, Dana;
Keough, Dianne T.;
Guddat, Luke W.;
Jersey, John de, Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase. Bioorganic and Medicinal Chemistry 2009, 17(17), 6218 - 6232, 10.1016/j.bmc.2009.07.044 .
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Holy, Antonin;
Dracinsky, Martin;
Jansa, Petr;
Votruba, Ivan;
Balzarini, Jan;
Klepetarova, Blanka;
Clercq, Erik de;
Janeba, Zlatko;
Baszczynski, Ondrej, Synthesis and antiviral activity of N-[3-fluoro-2- (phosphonomethoxy)propyl] analogues derived from N-substituted adenines and 2,6-diaminopurines. Bioorganic and Medicinal Chemistry 2011, 19(7), 2114 - 2124, 10.1016/j.bmc.2011.02.050 .
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Imramovsky, Ales;
Vinsova, Jarmila;
Polanc, Slovenko;
Kocevar, Marijan;
Jampilek, Josef;
Reckova, Zuzana;
Kaustova, Jarmila, A new modification of anti-tubercular active molecules. Bioorganic and Medicinal Chemistry 2007, 15(7), 2551 - 2559, 10.1016/j.bmc.2007.01.051 .
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Imramovsky, Ales;
Vinsova, Jarmila;
Ferriz, Juana Monreal;
Jampilek, Josef;
Kaustova, Jarmila;
Dolezal, Rafael;
Kunc, Filip, New antituberculotics originated from salicylanilides with promising in vitro activity against atypical mycobacterial strains. Bioorganic and Medicinal Chemistry 2009, 17(10), 3572 - 3579, 10.1016/j.bmc.2009.04.008 .
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Imramovsky, Ales;
Vavrova, Katerina;
Vinsova, Jarmila;
Kunc, Filip;
Ferriz, Juana M.;
Stolarikova, Jirina;
Vavrikova, Eva, Salicylanilide carbamates: Antitubercular agents active against multidrug-resistant Mycobacterium tuberculosis strains. Bioorganic and Medicinal Chemistry 2010, 18(3), 1054 - 1061, 10.1016/j.bmc.2009.12.055 .
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Bezouska, Karel;
Kavan, Daniel;
Hofbauerova, Katerina;
Kren, Vladimir;
Lhotak, Pavel;
Krenek, Karel;
Snajdrova, Renata;
Vancurova, Marketa;
Kadek, Alan;
Adamek, David;
Man, Petr;
Bojarova, Pavla, Carboxylated calixarenes bind strongly to CD69 and protect CD69 killer cells from suicidal cell death induced by tumor cell surface ligands. Bioorganic and Medicinal Chemistry 2010, 18(4), 1434 - 1440, 10.1016/j.bmc.2010.01.015 .
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Sedlak, Milos;
Ventura, Karel;
Kubicova, Lenka;
Staud, Frantisek;
Pravda, Martin;
Tycova, Katerina, Synthesis of pH-sensitive amphotericin B-poly(ethylene glycol) conjugates and study of their controlled release in vitro. Bioorganic and Medicinal Chemistry 2007, 15(12), 4069 - 4076, 10.1016/j.bmc.2007.03.083 .
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