Journal of Medicinal Chemistry
ISSN:
1520-4804
Articles
Naus, Petr;
Hocek, Michal;
Votruba, Ivan;
Pohl, Radek;
Dzubak, Petr;
Hajduch, Marian;
Birkus, Gabriel;
Wang, Ting;
Ray, Adrian S.;
Cihlar, Tomas;
Pichova, Iva;
Perlikova, Pavla;
Bourderioux, Aurelie;
Konecny, Petr;
Stray, Kirsten M.;
Feng, Joy Y., Synthesis and significant cytostatic activity of 7-hetaryl-7- deazaadenosines. Journal of Medicinal Chemistry 2011, 54(15), 5498 - 5507, 10.1021/jm2005173 
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Naus, Petr;
Hocek, Michal;
Slavetinska, Lenka;
Dzubak, Petr;
Hajduch, Marian;
Perlikova, Pavla;
Konecny, Petr;
Tloust'Ova, Eva;
Caletkova, Olga;
Bogdanova, Katerina;
Kolar, Milan;
Vrbkova, Jana, Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides. Journal of Medicinal Chemistry 2014, 57(3), 1097 - 1110, 10.1021/jm4018948 .
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Krecmerova, Marcela;
Holy, Antonin;
Dracinsky, Martin;
Masojidkova, Milena;
Andrei, Graciela;
Snoeck, Robert;
Balzarini, Jan;
De Clercq, Erik;
Pohl, Radek;
Cihlar, Tomas;
Naesens, Lieve;
Pomeisl, Karel;
Neyts, Johan;
Tichy, Tomas;
Brehova, Petra;
Laflamme, Genevieve;
Hui, Hon, Synthesis of ester prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] -2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. Journal of Medicinal Chemistry 2010, 53(19), 6825 - 6837, 10.1021/jm901828c .
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Hockova, Dana;
Janeba, Zlatko;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Wang, Tzu-Hsuan, Synthesis of novel N-branched acyclic nucleoside phosphonates as potent and selective inhibitors of human, plasmodium falciparum and plasmodium vivax 6-oxopurine phosphoribosyltransferases. Journal of Medicinal Chemistry 2012, 55(13), 6209 - 6223, 10.1021/jm300662d .
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Hockova, Dana;
Slavetinska, Lenka;
Janeba, Zlatko;
Naesens, Lieve;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Tichy, Tomas;
Spacek, Petr;
Wang, Tzu-Hsuan;
Edstein, Michael D.;
Chavchich, Marina, Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity. Journal of Medicinal Chemistry 2013, 56(6), 2513 - 2526, 10.1021/jm301893b .
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Novak, Petr;
Kotora, Martin;
Bartunek, Petr;
Sedlak, David, Synthesis and evaluation of 17α-Arylestradiols as ligands for estrogen receptor α and β. Journal of Medicinal Chemistry 2010, 53(10), 4290 - 4294, 10.1021/jm901898a .
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Dracinsky, Martin;
Kotora, Martin;
Eignerova, Barbara;
Bartunek, Petr;
Sedlak, David, Synthesis and biochemical characterization of a series of 17α-perfluoroalkylated estradiols as selective ligands for estrogen receptor α. Journal of Medicinal Chemistry 2010, 53(19), 6947 - 6953, 10.1021/jm100563h .
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Krecmerova, Marcela;
Hockova, Dana;
Vrbkova, Silvie;
Keough, Dianne T.;
De Jersey, John;
Guddat, Luke W.;
Rejman, Dominik;
Spacek, Petr;
Eng, Wai Soon;
Jans, Harmen;
West, Nicholas P.;
Naesens, Lieve M.J., Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: Potential for new antibacterial agents. Journal of Medicinal Chemistry 2013, 56(17), 6967 - 6984, 10.1021/jm400779n .
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Saman, David;
Sklenar, Vladimir;
Ledvina, Miroslav;
Zyka, Daniel;
Bezouska, Karel;
Kovalova, Anna;
Kubickova, Monika;
Zidek, Lukas;
Pompach, Petr;
Kavan, Daniel;
Bily, Jan;
Vanek, Ondrej;
Kubinkova, Zuzana;
Libigerova, Martina;
Ivanova, Ljubina;
Antolikova, Maria;
Mrazek, Hynek;
Rozbesky, Daniel;
Hofbauerova, Katerina;
Kren, Vladimir, Synthetic N -Acetyl- d -glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69 killer lymphocytes upon dimerization via a hydrophilic flexible linker. Journal of Medicinal Chemistry 2010, 53(10), 4050 - 4065, 10.1021/jm100055b .
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Pohl, Radek;
Rosenberg, Ivan;
Rejman, Dominik;
Panova, Natalya;
Klener, Pavel;
Maswabi, Bokang, N -phosphonocarbonylpyrrolidine derivatives of guanine: A new class of Bi-substrate inhibitors of human purine nucleoside phosphorylase. Journal of Medicinal Chemistry 2012, 55(4), 1612 - 1621, 10.1021/jm201409u .
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Cisarova, Ivana;
Brynda, Jiri;
Vesely, Jan;
Cigler, Petr;
Rezacova, Pavlina;
Schimer, Jiri;
Grantz Saskova, Klara;
Lepsik, Martin;
Kozisek, Milan;
Oberwinkler, Heike;
Kraeusslich, Hans-Georg;
Konvalinka, Jan, Structure-aided design of novel inhibitors of HIV protease based on a benzodiazepine scaffold. Journal of Medicinal Chemistry 2012, 55(22), 10130 - 10135, 10.1021/jm301249q .
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